Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Bin Xiao"'
Rheb1-Independent Activation of mTORC1 in Mammary Tumors Occurs through Activating Mutations in mTOR
Autor:
Richard F. Lamb, Dongmei Zuo, William J. Muller, Bin Xiao, Robert D. Cardiff, Nahum Sonenberg, Alison Hirukawa
Publikováno v:
Cell Rep
Cell Reports, Vol 31, Iss 4, Pp-(2020)
Cell Reports, Vol 31, Iss 4, Pp-(2020)
Summary: Mechanistic target of rapamycin complex 1 (mTORC1) is a master modulator of cellular growth, and its aberrant regulation is recurrently documented within breast cancer. While the small GTPase Rheb1 is the canonical activator of mTORC1, Rheb1
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
To study the relationship between chromatin condensation, gene transcription and developmental competence during oocyte maturation and to explore the mechanisms by which meiotic arrest maintenance (MAM) and sexual maturity improve oocyte competence,
Defective mitophagy linked to dysfunction in the proteins Parkin and PTEN-induced putative kinase 1 (PINK1) is implicated in the pathogenesis of Parkinson's disease. Although the mechanism by which Parkin mediates mitophagy in a PINK1-dependent manne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e2b2b38565d938d834001262cfca734
https://europepmc.org/articles/PMC5633131/
https://europepmc.org/articles/PMC5633131/
Autor:
Chuanxi Cai, Zhenhua Yuan, Ruhang Tang, Juan Li, Bo He, Bin Xiao, Noah Weisleder, Chunping Qiao, Hua Zhu, Xiao Xiao, Christina Mayer, Jianbin Li, Jianjie Ma, Pei-Hui Lin
Publikováno v:
Molecular therapy : the journal of the American Society of Gene Therapy. 20(4)
Muscular dystrophies (MDs) are caused by genetic mutations in over 30 different genes, many of which encode for proteins essential for the integrity of muscle cell structure and membrane. Their deficiencies cause the muscle vulnerable to mechanical a