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Autor:
Adam Rumjon
Publikováno v:
Medicine. 51:196-200
Anaemia is a common complication of chronic kidney disease. The most important contributory factor is an abnormally low circulating concentration of erythropoietin, which is produced by the kidney peritubular cells. Anaemia of kidney disease is likel
Publikováno v:
BMJ Case Rep
A man in his early 40s with no significant vascular risk factors was managed within a period of 6 months for recurrent vascular events: ischaemic stroke, transient ischaemic attack and isolated third nerve palsy. He was extensively investigated throu
Publikováno v:
BMJ Case Rep
Gastrointestinal stromal tumours (GISTs) are the most common mesenchymal neoplasms of the gastrointestinal tract. Dedifferentiation in these tumours occurs rarely, and when it does occurs most commonly after prolonged treatment with imatinib. We repo
Autor:
Juergen Rech, Andreas Ramming, David Simon, Cong Duy Bui, Holger Bang, Axel J. Hueber, Georg Schett, Arnd Kleyer
Publikováno v:
Arthritis and Rheumatology
To assess if microstructural bone lesions in individuals at risk of developing rheumatoid arthritis (RA) are related to the spectrum of anti-modified protein antibodies (AMPAs) and affect the risk of developing RA.Cortical microchannels as well as co
Autor:
Sarah Lecordier, Paul Préfontaine, Ayman ElAli, Mohammed A. Al-Onaizi, Peter Thériault, Serge Rivest
Publikováno v:
Brain, Behavior, and Immunity. 99:363-382
Alzheimer’s disease (AD) pathology is characterized by amyloid-β (Aβ) deposition and tau hyper-phosphorylation, accompanied by a progressive cognitive decline. Monocytes have been recently shown to play a major role in modulating Aβ pathology, a
Autor:
E. Vazi, F. Holanda, C.V. Cardoso, Neife Aparecida Guinaim dos Santos, Eduardo Fernandes Bondan, Maria Marlene Martins
Publikováno v:
Research in Veterinary Science. 138:39-48
Methotrexate (MTX), an antifolate drug, is widely used in chemotherapeutic protocols for metastatic and primary brain tumors and some autoimmune diseases. Its efficacy for brain tumors is limited by the high incidence of central nervous system (CNS)
Autor:
Ekram Nemr Abd Al Haleem, Sawsan Abo Bakr Zaytoon, Fatma Al –Zahraa Mohamed Ibrahim, Hossam M.M. Arafa
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 99:864-874
Peptic ulcers are one of the world's major gastrointestinal disorders, embracing both gastric and duodenal ulcers, and affecting 10% of the world population. The current study aimed to investigate the possible protective effect of tadalafil and pento
Publikováno v:
INTERNATIONAL JOURNAL OF ENDOCRINOLOGY (Ukraine). 15:376-380
Актуальність. Одним з органів-мішеней при цукровому діабеті (ЦД) є центральна нервова система, гіперглікемічні пошкодження якої проявля
Autor:
Thomas Krasemann, Dietmar Schranz
Publikováno v:
Cardiology in the Young, 31(8), 1323-1326. Cambridge University Press
NPC-QIC Registry data showed that angiotensin-converting enzyme inhibitors were described in almost 38% for patients with single ventricle physiology after stage-I Norwood palliation. However, mortality and ventricular dysfunction or atrioventricular
Publikováno v:
Journal of Clinical Pharmacy and Therapeutics
What is known and objective Methotrexate‐associated lymphoproliferative disorder (MTX‐LPD) is a rare complication that develops in patients treated with methotrexate (MTX). Case summary A 76‐year‐old male patient had been taking MTX for his r