Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Margery A. Connelly"'
Autor:
Robin P. F. Dullaart, Margery A. Connelly, Stephan J. L. Bakker, B. D. Westenbrink, Dion Groothof, Adrian Post, Jose L. Flores-Guerrero, Eke G. Gruppen, Erwin Garcia, Eline H. van den Berg
Publikováno v:
European Journal of Clinical Investigation, 51(12):13627, 1-12. Wiley
Background Nonalcoholic fatty liver disease (NAFLD) is increasingly prevalent, paralleling the obesity epidemic. Ketone bodies are produced in the liver, but it is currently uncertain whether circulating ketone bodies are increased in the context of
Autor:
B. D. Westenbrink, James D. Otvos, Robin P. F. Dullaart, Margery A. Connelly, Erwin Garcia, Jose L. Flores-Guerrero, Irina Shalaurova, Gerjan Navis, Stephan J. L. Bakker, Dion Groothof, Rudolf A. de Boer
Publikováno v:
European Journal of Clinical Investigation, 51(5):13468. Wiley
European Journal of Clinical Investigation
European Journal of Clinical Investigation
Background In the failing heart, energy metabolism is shifted towards increased ketone body oxidation. Nevertheless, the association of beta-hydroxybutyrate (beta-OHB) with development of heart failure (HF) remains unclear. We investigated the associ
Autor:
Sara Sokooti, Robin P. F. Dullaart, Margery A. Connelly, Stephan J. L. Bakker, Jose L. Flores-Guerrero, Hiddo J.L. Heerspink, Lyanne M. Kieneker
Publikováno v:
The Journal of Clinical Endocrinology and Metabolism
The Journal of Clinical Endocrinology & Metabolism
Journal of Clinical Endocrinology and Metabolism, 106(6), 1761-1772. ENDOCRINE SOC
The Journal of Clinical Endocrinology & Metabolism
Journal of Clinical Endocrinology and Metabolism, 106(6), 1761-1772. ENDOCRINE SOC
ContextHigh-density lipoproteins (HDL) may be protective against type 2 diabetes (T2D) development, but HDL particles vary in size and function, which could lead to differential associations with incident T2D. A newly developed nuclear magnetic reson
Autor:
Robin P. F. Dullaart, Margery A. Connelly, Stephan J. L. Bakker, Hiddo J.L. Heerspink, Tamas Szili-Torok, Jenny E. Kootstra-Ros, António W Gomes-Neto, Maryse C J Osté, Sara Sokooti, Jose L. Flores-Guerrero
Publikováno v:
Biomolecules, Vol 10, Iss 3, p 481 (2020)
Biomolecules, 10(3):481. MDPI AG
Biomolecules
Volume 10
Issue 3
Biomolecules, 10(3):481. MDPI AG
Biomolecules
Volume 10
Issue 3
High concentrations of high-density lipoprotein (HDL) cholesterol are likely associated with a lower risk of posttransplantation diabetes mellitus (PTDM). However, HDL particles vary in size and density with yet unestablished associations with PTDM r
Autor:
Justyna Wolak-Dinsmore, Margery A. Connelly, Stanley L. Hazen, Dennis W. Bennett, James D. Otvos, Elias J. Jeyarajah, Erwin Garcia, Xinmin S. Li, Zeneng Wang
Publikováno v:
Clinical Biochemistry. 50:947-955
Background and objectives Trimethylamine- N -oxide (TMAO) produced by gut microbiota metabolism of dietary choline and carnitine has been shown to be associated with increased risk of cardiovascular disease (CVD) and to provide incremental clinical p
Publikováno v:
Clinica Chimica Acta. 459:177-186
The physiological function initially attributed to the oligosaccharide moieties or glycans on inflammatory glycoproteins was to improve protein stability. However, it is now clear that glycans play a prominent role in glycoprotein structure and funct
Autor:
Wim J. Sluiter, Stephan J. L. Bakker, Eke G. Gruppen, Robin P. F. Dullaart, Margery A. Connelly
Publikováno v:
Clinica chimica acta, 488, 7-12. ELSEVIER SCIENCE BV
Objective: Elevated circulating levels of pro-inflammatory biomarkers are associated with adverse health effects, but the extent to which enhanced low-grade inflammation influences remaining life expectancy (LE) is uncertain. GlycA is a novel pro-inf
Autor:
Esther O Granville, Lucy W. Piner, Margery A. Connelly, Leslie H. Willis, Kim M. Huffman, Lori A. Bateman, David B. Bartlett, Cris A. Slentz, Connie W. Bales, William E. Kraus
Publikováno v:
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity, Vol 2017 (2017)
Oxidative Medicine and Cellular Longevity, Vol 2017 (2017)
GlycA is a new composite measure of systemic inflammation and a predictor of many inflammatory diseases. GlycA is the nuclear magnetic resonance spectroscopy-derived signal arising from glucosamine residues on acute-phase proteins. This study aimed t
Publikováno v:
Lipids in Health and Disease
Lipids in Health and Disease, 15:143. BioMed Central Ltd.
Lipids in Health and Disease, 15:143. BioMed Central Ltd.
Background: The choline metabolite, betaine, plays a role in lipid metabolism, and may predict the development of cardiovascular disease and type 2 diabetes mellitus (T2DM). Phospholipid transfer protein (PLTP) and lecithin: cholesterol acyltransfera
Autor:
Margery A. Connelly, Michael K. Hansen, Jenson Qi, Fuyong Du, Gary W. Caldwell, Wensheng Lang, Gee-Hong Kuo, Yin Liang, Michael David Gaul, Tonya Martin, Alessandro Pocai, Seunghun Paul Lee
Publikováno v:
Analytical biochemistry. 524
Monoacylglycerol acyltransferase 2 (MGAT2) catalyzes the synthesis of diacylglycerol (DAG) from free fatty acids (FFA) and sn-monoacylglycerol (MG), the two major hydrolysis products of dietary fat. To demonstrate MGAT2-mediated cellular activity of