Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Michel Laviolette"'
Autor:
Ma'en Obeidat, Krystelle Godbout, Kim Valette, Philippe Joubert, Louis-Philippe Boulet, Sébastien Thériault, Maarten van den Berge, Patrick Mathieu, Arnaud Chignon, Catherine Labbé, Valentin Bon-Baret, Jean-Christophe Bérubé, Jennifer Lamothe, Nathalie Gaudreault, Aida Eslami, David C. Nickle, Ke Hao, Don D. Sin, Zhonglin Li, Michel Laviolette, Wim Timens, Andréanne Côté, Yohan Bossé
Publikováno v:
Communications Biology
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Communications biology, 4(1):700. Nature Publishing Group
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Communications biology, 4(1):700. Nature Publishing Group
To identify candidate causal genes of asthma, we performed a genome-wide association study (GWAS) in UK Biobank on a broad asthma definition (n = 56,167 asthma cases and 352,255 controls). We then carried out functional mapping through transcriptome-
Autor:
Michel Laviolette, Isabelle Dubuc, Younes Zaid, Nicolas Flamand, Louis Flamand, Olivier Flamand, Anne Sophie Archambault, Étienne Doré, Eric Boilard
Publikováno v:
The Journal of Allergy and Clinical Immunology
Background Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection can lead to a variety of clinical outcomes ranging from the absence of symptoms to severe acute respiratory disease and ultimately death. A feature of patients with sev
Autor:
Michel Laviolette, Suzanne Maahs, Veronica A. Swystun, Louis-Philippe Boulet, Irvin Mayers, Christopher Carlsten, Philip J. Lowe, Barbro Dahlén, Andrej Skerjanec, Miranda Bowen, Richard Leigh, Linda Hui, Beth E. Davis, Richard M. Watson, Gail M. Gauvreau, Kieran J. Killian, Joanne Milot, Anton Drollmann, Paul M. O'Byrne, J. Mark FitzGerald, Ann-Sofie Lantz, Karin Meiser, Nikolaos Lazarinis, Jonathan P. Arm, Donald W. Cockcroft
Publikováno v:
Journal of Allergy and Clinical Immunology. 138:1051-1059
Background Omalizumab is an established anti-IgE therapy for the treatment of allergic diseases that prevents IgE from binding to its receptor. QGE031 is an investigational anti-IgE antibody that binds IgE with higher affinity than omalizumab. Object
Autor:
William W Busse, Eugene R Bleecker, J Mark FitzGerald, Gary T Ferguson, Peter Barker, Stephanie Sproule, Richard F Olsson, Ubaldo J Martin, Mitchell Goldman, Anahí Yañez, Marcelo Fernández, Alberto Tolcachier, Juan Belloni, Jorge Taborda, Maria De Salvo, Jorge Maspero, Carlos Victorio, Miguel Chirino Navarta, Monica Grilli, Pablo Rodríguez, María Otaola, Víctor Cambursano, Patricia Malamud, Ana Stok, German Arce, Osiris Roza, Fernando Scherbovsky, Pedro Elias, Maria Salazan Saez, Matthew Peters, Martin Phillips, John Upham, Peter Gibson, Francis Thien, Jo Douglass, Paul Thomas, Philip Bardin, Dimitar Sajkov, Mark Hew, David Langton, Andreia Pez, Carlos Fritscher, Jorge Hetzel, Waldo Mattos, Rafael Stelmach, Martti Antila, Ana Luisa Fernandes, Hristo Metev, Yavor Ivanov, Aneliya Bogdanova, Ana Dancheva Markova, Marinka Peneva, Rumyana Veselinova, Tatyana Petkova, Vanushka Petrova, Elena Shopova, Yuliya Ivanova, Rumyana Yotsova, Ginka Kirkova, Galina Petrova, Svetoslav Dachev, Kostadinka Sotirova, Mariyana Stoyanova, Oleg Yakov, Vanya Ilieva-Fartunova, Catherine Lemiere, Michel Laviolette, William Yang, Bonavuth Pek, William Patrick Killorn, Claude Poirier, Guy Chouinard, Lyle Melenka, Richard Leigh, Parameswaran Nair, Delbert Dorscheid, James Martin, Juana Pavie, Andres Rosenblut, Claudia Cartagena, Carlos Quilodran, Silvia Muñoz, Ivana Malkusova, Josef Veverka, Stanislav Holub, Jaroslav Mares, Radovan Kozel, Daniela Kopecka, Vladimir Zindr, Pavel Cerva, Pascal Chanez, Arnaud Bourdin, Gilles Devouassoux, Camille Taille, Frédéric De Blay, Francois Goupil, Christophe Leroyer, Delphine Gourcerol, Toufik Didi, Alain Didier, Gilles Garcia, Philippe Bonniaud, Riazate Rossanaly Vasram, Marek Lommatzsch, Ulf Harnest, Anneliese Linnhoff, Claus Keller, Gerhard Hoheisel, Karin Förster, Thomas Schultz, Isabelle Schenkenberger, Joachim Kirschner, Tibor Schmoller, Stefan Zielen, Marc Kornmann, Ekkehard Beck, Lutz Volgmann, Rolf Dichmann, Axel Overlack, Jörg Winkler, Petra Mikloweit, Sabine Ballenberger, Mathias Rolke, Stephanie Korn, Helmut Pabel, Martin Hoffmann, Jan Feimer, Klaus Rabe, Regina Deckelmann, Tobias Welte, Hiroyuki Ohbayashi, Soichiro Hozawa, Terufumi Shimoda, Makoto Yoshida, Toshikazu Nagakura, Tadashi Kamei, Yasuyuki Sano, Shinichiro Kagami, Hisaho Takahashi, Michiko Haida, Goro Kimura, Hiroyuki Nakamura, Yasuo To, Masaharu Shinkai, Tadasuke Shimokawaji, Makoto Kudo, Noriharu Shijyubo, Takao Tochigi, Motokazu Kato, Akihiko Tanaka, Yasuhiro Gon, Norihisa Sasaki, Tetsuro Ohdaira, Chiharu Omori, Toshiki Takahashi, Satomi Takeuchi, Kiyotaka Nakajima, Hironi Makita, Masahiro Kaneko, Kenjiro Furuta, Masami Taniguchi, Yoshito Inobe, Hiroshi Miki, Yoichi Nakamura, Naoki Miyazawa, Shuichi Yano, Masayuki Iijima, Tsuyoshi Yamato, Javier Diaz, Alberto Matsuno, Efrain Felix, Alfredo Guerreros, Alejandro Daly, Fernando Rodriguez Chariarse, Danilo Salazar, Socorro Castro, William Chavez, Rolando Estrella, Teresita Aquino, Tito Atienza, Ronnie Samoro, Marie Grace Dawn Isidro, Piotr Kuna, Adam Antczak, Michał Bednarek, Danuta Mądra-Rogacka, Teresa Hofman, Marek Jutel, Ewa Pisarczyk-Bogacka, Agata Kot, Robert Mróz, Małgorzata Czupryńska-Borkowska, Małgorzata Żurowska-Gębala, Andrzej Dyczek, Grażyna Jasieniak-Pinis, Piotr Wojnowski, Ewa Trębas-Pietraś, Małgorzata Dobryniewska, Marcin Stobiecki, Marzenna Tarnowska-Matusiak, Alina Magner, Andrzej Kolczyński, Tomasz Kachel, Zbigniew Bartuzi, Bernadetta Majorek-Olechowska, Paweł Śliwiński, Violetta Balicka, Elżbieta Hajoł, Jacek Stachera, Marta Rachel, Marek Michnar, Jarosław Tałałaj, Ewa Springer, Piotr Napora, Tomasz Grzelewski, Renata Bijata-Bronisz, Anna Świderska, Grzegorz Mincewicz, Zbigniew Sankowski, Tomasz Fijołek, Artur Kwaśniewski, Joanna Jerzyńska, Jerzy Cygler, Ryszard Olesiejuk, Iwona Von Steiner, Wojciech Machowiak, Krzysztof Filipek, Piotr Piskorz, Ewa Uhryn, Marita Nittner-Marszalska, Elżbieta Rybicka-Liszewska, Anna Bodzenta-Łukaszyk, Marta Chełmińska, Izabella Krupa-Borek, Wojciech Skucha, Anna Płoszczuk, Traian Mihaescu, Ioan Dorin Petrui, Angelica Savu, Ghiulten Apti, Claudia Toma, Ana Trailescu, Sergei Sokurenko, Vasiliy Trofimov, Igor Leshchenko, Natalia Shaporova, Inna Ilyashevich, Irina Stitsenko, Alexander Vizel, Yulia Ilkovich, Dmitrii Tikhanov, Svetlana Goncharova, Andrey Ezhov, Galina Ignatova, Nadezhda Izmozherova, Nadezhda Berdnikova, Ludmila Goryachkina, Veronika Popova, Laura Bolieva, Andrey Rebrov, Vladimir Nosov, Olga Magnitskaya, Sergey Nedogoda, Vladimir Abrosimov, Artem Molotkov, Galina Reshedko, Mikhail Smirnov, Marina Osipenko, Elena Pavlysh, Svetlana Myasoedova, Liudmila Lenskaya, Valery Chistyakov, Elena Vishneva, Liliya Uon, Anna Zateyschikova, Svetlana Laleko, Tatiana Pak, Axel Bruning, Visvakuren Naidoo, Jeevren Reddy, Richard Van Zyl Smit, Hae-Sim Park, Young Joo Cho, Sang-Heon Cho, Sang Haak Lee, Byung Jae Lee, Ju Sang Kim, You Sook Cho, Choon-Sik Park, Mi-Kyeong Kim, Young-Il Koh, Joo-Hee Kim, Sook Young Lee, Sang Pyo Lee, Jung Won Park, Kwang Ha Yoo, Hyoungkyu Yoon, Jaechun Lee, Gyu-Young Hur, Soo Keol Lee, HeeKyoo Kim, David Ramos Barbón, Elena Laffond Yges, Eva Martínez Moragón, Miguel Arias Guillen, Alberto Saura Vinuesa, Fernando Sánchez-Toril López, José Luis Velasco Garrido, Borja García-Cosio Piqueras, Luis Pérez de Llano, Antonio Luis Valero Santiago, Myriam Calle Rubio, Leif Bjermer, Bo Lundbäck, Bilun Gemicioglu, Sevim Bavbek, Dane Ediger, Munevver Erdinc, Ismail Hanta, Sibel Nayci, Sibel Arinc, Liudmyla Iashyna, Yuriy Mostovoy, Mykola Ostrovskyy, Lesia Kuryk, Ivan Lemko, Tetyana Ospanova, Liubov Moskalenko, Oleksii Korzh, Viktor Blazhko, Olena Krakhmalova, Liliia Romaniuk, Yevgeniya Dytyatkovs'ka, Oleh Yakovenko, Volodymyr Gavrysyuk, Hassan Burhan, Dinesh Saralaya, Stephen Scott, Alyn Morice, Ewart Jackson-Voyzey, Thida Win, Shuab Nasser, Richard Harrison, Rekha Chaudhuri, Monica Nordstrom, Pradip De, Matthew Masoli, Adel Mansur, Anthony Gunstone, Robert Niven, Timothy Harrison, Suresh Babu, Subodh Bhuchar, Shahrukh Kureishy, John Zwetchkenbaum, Lawrence Kaplan, Eugene Bleecker, Santiago Reyes, Faisal Fakih, Marvin Heuer, Ryan Klein, Michael Marcus, Iftikhar Hussain, Tonny Tanus, Hengameh Raissy, Sady Alpizar, Hector Rodriguez, Gerald Gleich, Tracy Bridges, Joe Pouzar, Gary Steven, Jonathan Matz, Shana Krstevska, Dama Ziworitin, Adolfo Kaplan, James Sublett, James DeAngelo, Amy Darter, John Agaiby, John Hagan, Enrique Davis, Dareen Siri, Charlene Mcevoy, Chrisette Dharma, Najmuddin Karimjee, Steven Kelsen, Manuel Frade, Amy Silverthorn, Joel Kline, Francis Averill, Jose Ruiz, Emory Robinette, Zeeshan Shaikh, Carlos Aguilar, William Nish, German Alvarez, Younus Ismail, Purvi Parikh, Mila Leong, Dennis Murphy, Francisco Garcia, Alan Goldsobel, Antonio Blanco, Edward Campbell, Guido Perez, Geoffrey Chupp, Toby Bates, Vandely Perez, Sally Wenzel, Kartik Shenoy, Rohit Katial, David Bernstein, Neil Parikh, William Sims, Gary Ferguson, David Pham, Anu George, Richard Beasley, Gilberto Perez, Robert Garver, Miriam Garcia-Portela, Stephen Wong, Weily Soong, Richard Guillot, Golda Hudes, Ahmed Arif, Josefa Binker, Manuel Villareal, Ulrike Ziegner, Joseph Ojile, Sanjeev Goswami, Carlos Piniella, Ilia Segal, Heidi Zafra, Mitchell Lee, Martha Tarpay, John Panuto, Rajan Merchant, Peter Springsteen, Timothy Scialla, Paul Shapero, Karen Allen, Mark Moss, Humberto Cruz, Jeffrey Rumbyrt, Amy Boyd, Robert Nathan, Jonathan Bernstein, Joshua Jacobs, Elliot Ginchansky, Janice Johnston, Barbara Baxter, Thomas Johnson II, Stephen Apaliski, Clinton Corder, David Fuentes, Joseph Diaz, Chau Ngo, Lan Le
Publikováno v:
Lancet Respiratory medicine
Lancet Respiratory medicine, Elsevier, 2019, 7 (1), pp.46-59. ⟨10.1016/S2213-2600(18)30406-5⟩
Lancet Respiratory medicine, Elsevier, 2019, 7 (1), pp.46-59
The Lancet Respiratory Medicine
The Lancet Respiratory Medicine, 2019, 7 (1), pp.46-59. ⟨10.1016/S2213-2600(18)30406-5⟩
Lancet Respiratory medicine, Elsevier, 2019, 7 (1), pp.46-59. ⟨10.1016/S2213-2600(18)30406-5⟩
Lancet Respiratory medicine, Elsevier, 2019, 7 (1), pp.46-59
The Lancet Respiratory Medicine
The Lancet Respiratory Medicine, 2019, 7 (1), pp.46-59. ⟨10.1016/S2213-2600(18)30406-5⟩
Benralizumab is an interleukin-5 receptor α-directed cytolytic monoclonal antibody that has been shown to safely reduce exacerbations and improve lung function for patients with asthma. We assessed the long-term safety and efficacy of benralizumab f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed0807d2067546999db31f931325a88a
https://hal.univ-brest.fr/hal-02052347
https://hal.univ-brest.fr/hal-02052347
Autor:
Peter H. Howarth, Lars H. Nordenmark, Michel Laviolette, Himanshu Parikh, Vibeke Backer, Tina Skjold, Salman Siddiqui, Ingrid Louise Titlestad, Ronald Olivenstein, Dave Singh, Læge Carl Nielsen, Richard J. Russell, Gene L. Colice, Martin Braddock, Millie Wang, Latifa Chachi, Christopher E. Brightling, Lorcan McGarvey, Rekha Chaudhuri, Charlotte Suppli Ulrik, David Cohen, Brian Leaker, J. Mark FitzGerald, Tim Harrison
Publikováno v:
Russell, R J, Chachi, L, FitzGerald, J M, Backer, V, Olivenstein, R, Titlestad, I L, Ulrik, C S, Harrison, T, Singh, D, Chaudhuri, R, Leaker, B, McGarvey, L, Siddiqui, S, Wang, M, Braddock, M, Nordenmark, L H, Cohen, D, Parikh, H, Colice, G, Brightling, C E, Laviolette, M, Skjold, T, Nielsen, L C & Howarth, P 2018, ' Effect of tralokinumab, an interleukin-13 neutralising monoclonal antibody, on eosinophilic airway inflammation in uncontrolled moderate-to-severe asthma (MESOS) : a multicentre, double-blind, randomised, placebo-controlled phase 2 trial ', The Lancet Respiratory Medicine, vol. 6, no. 7, pp. 499-510 . https://doi.org/10.1016/S2213-2600(18)30201-7
Summary Background The role of interleukin 13 in airway inflammation and remodelling in asthma is unclear. Tralokinumab is a human monoclonal antibody that neutralises interleukin 13. We aimed to evaluate whether tralokinumab would have an effect on
Publikováno v:
Clinical Epigenetics
Allergic rhinitis is a common chronic disorder characterized by immunoglobulin E-mediated inflammation. To identify new genes associated with this trait, we performed genome- and epigenome-wide association studies and linked marginally significant Cp
Autor:
Gary T Ferguson, J Mark FitzGerald, Eugene R Bleecker, Michel Laviolette, David Bernstein, Craig LaForce, Lyndon Mansfield, Peter Barker, Yanping Wu, Maria Jison, Mitchell Goldman, Guy Chouinard, Maryam Rostami, Jean Oosthuizen, Bonavuth Pek, Deepen Patel, Pierre-Alain Houle, Sohail Khattak, Patrick Killorn, Claus Keller, Isabelle Schenkenberger, Stefan Zielen, Sabine Ballenberger, Martin Hoffmann, Joachim Kirschner, Márta Papp, Teréz Kecskés, Magdolna Póczi, Lajos Molnár, Éva Radeczky, Judit Schlezák, Ewa Springer, Violetta Balicka, Jadwiga Kaczmarek, Danuta Madra-Rogacka, Ewa Pisarczyk-Bogacka, Malgorzata Zurowska-Gebala, Maciej Marczak, Piotr Napora, Witold Pomiecko, Erika Pribulova, Svetlana Kurthova, Maria Drugdova, Denisa Kavkova, Luboslava Frajtova, Alexander Golubov, Dagmar Paulinyova, Daniela Hasicova, Miriam Michalickova, Miguel Trevino, Charles Campbell, Andrew Wachtel, Eugene Bleecker, Selwyn Spangenthal, Edward Kerwin, Paul Ratner, Samir Arora, Gregory Feldman, Benedict Okwara, Humberto Cruz, Lawrence Sher, Andrew Pedinoff, Clinton Corder
Publikováno v:
The Lancet. Respiratory medicine. 5(7)
Summary Background Benralizumab is a humanised, anti-interleukin 5 receptor α monoclonal antibody that directly and rapidly depletes eosinophils, reduces asthma exacerbations, and improves lung function for patients with severe eosinophilic asthma.
Autor:
Catherine Labbé, Paula A. Ugalde, Alisson Clemenceau, Philippe Joubert, Michel Laviolette, Nathalie Gaudreault, Yohan Bossé, Cyndi Henry
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0207513 (2018)
PLoS ONE
PLoS ONE
BackgroundPrognostic biomarkers are needed in clinical setting to predict outcome after resection for early-stage lung adenocarcinoma. The goal of this study is to validate tumor-based single-gene expression biomarkers with demonstrated prognostic va
Autor:
Nora Franceschini, Jing Hua Zhao, Vilmundur Gudnason, James C. Hogg, Nick Fishbane, Wenbo Tang, Ian P. Hall, Andrew J. Sandford, Sina A. Gharib, Michel Laviolette, Louise V. Wain, Pirro G. Hysi, David P. Strachan, Martin D. Tobin, Traci M. Bartz, Beate Stubbe, Patricia A. Cassano, Rajesh Rawal, Daan W. Loth, Jennie Hui, Dirkje S. Postma, George T. O'Connor, Peter D. Paré, James F. Wilson, Yunlong Nie, Ke Hao, Ozren Polasek, Caroline Hayward, W. Mark Elliott, Mika Kähönen, María Soler Artigas, Don D. Sin, Albert V. Smith, Guy Brusselle, Kari E. North, David C. Nickle, Ma'en Obeidat, Jemma B. Wilk, Marjo-Riitta Järvelin, Wim Timens, Deborah Jarvis, Holger Schulz, Jaakko Kaprio, Stephanie J. London, Denise Daley, Yohan Bossé
Publikováno v:
The Lancet Respiratory Medicine, 3(10), 782-795. Elsevier Ltd.
The Lancet. Respiratory Medicine, 3(10), 782-795. ELSEVIER SCI LTD
The Lancet. Respiratory Medicine, 3(10), 782-795. ELSEVIER SCI LTD
Summary Background Lung function measures reflect the physiological state of the lung, and are essential to the diagnosis of chronic obstructive pulmonary disease (COPD). The SpiroMeta-CHARGE consortium undertook the largest genome-wide association s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26020e2f0a665e850563d97421ebd5be
http://hdl.handle.net/10138/224296
http://hdl.handle.net/10138/224296