Zobrazeno 101 - 110
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Role of Sciellin in gallbladder cancer proliferation and formation of neutrophil extracellular traps
Autor:
Huijie Miao, Yingbin Liu, Liguo Liu, Yang Li, Yijian Zhang, Yongsheng Li, Yang Yang, Yunping Hu, Qindie Xu, Tai Ren, Bo Yang, Chen Cai, Ruiyan Yuan, Chengkai Jiang
Publikováno v:
Cell Death and Disease, Vol 12, Iss 1, Pp 1-13 (2021)
Cell Death & Disease
Cell Death & Disease
Apart from primary tumor development and metastasis, cancer-associated thrombosis is the second cause of cancer death in solid tumor malignancy. However, the mechanistic insight into the development of gallbladder cancer (GBC) and cancer-associated t
Publikováno v:
International Journal of Medical Sciences
The incidence of cutaneous melanoma (CM) increased since the 1970s, and also along with an unfavorable prognosis. CM patients have been verified benefits from immunotherapy, and granzymes (GZMs) comprise more than 90% of the cytolytic granules secret
Autor:
Jiarun Zhang, Xiuyue Yu, Xiaotong Zhang, Zhe Zhang, Xuejie Li, Chuize Kong, Lei Yin, Jinlong Yao, Yang Liu, Xi Liu, Hao Zhang
Publikováno v:
Journal of Cellular and Molecular Medicine
Much progress has been made in understanding the mechanism of bladder cancer (BC) progression. Protein kinase C‐α (PKCα) is overexpressed in many kinds of cancers. Additionally, PKCα is considered an oncogene that regulates proliferation, invasi
Autor:
O. van Hooij, S. Fussek, Tilly Aalders, Gerald W. Verhaegh, P M C Pinto, J.A. Schalken, C G H Rönnau, Martin Burchardt, Frank Smit
Publikováno v:
World Journal of Urology, 39, 3789-3797
World Journal of Urology, 39, 10, pp. 3789-3797
World Journal of Urology
World Journal of Urology, 39, 10, pp. 3789-3797
World Journal of Urology
Purpose Prostate cancer (PCa) is a leading cause of cancer-related death. Upon androgen-deprivation therapy, the disease may progress further to castration-resistant PCa (CRPC) with a poor prognosis. MicroRNAs (miRNAs) are small non-coding RNAs, whic
Autor:
Kenichi Mizutani, Shilei Zhao, Reimon Yamaguchi, Xin Guo, Hidetaka Uramoto, Chundong Gu, Sohsuke Yamada
Publikováno v:
International Journal of Medical Sciences
Background: Teashirt homolog 2 (TSHZ2) is essential for maintaining cellular homeostasis and regulating transcription on neoplasia development. However, the regulation of TSHZ2 in lung tumorigenesis and the underlying mechanisms remain unclear. Objec
Publikováno v:
Anticancer Research. 41:101-111
Background/aim The expression of tumor-associated programmed death-ligand 1 (PD-L1) predicts clinical responses to PD-1-directed immunotherapy. The expression levels of PD-L2, another PD-1 ligand, and its relationship with responses to PD-1-targeting
Publikováno v:
Carcinogenesis
The neoplastic Hodgkin/Reed-Sternberg (HRS) cells of classical Hodgkin lymphoma (cHL) depend on chronic activation of the Janus kinase (JAK)/signal transducer and activator of transcription (STAT) signalling pathways to maintain survival and prolifer
Autor:
Xinru Kong, Zhongju Fang, Jixia Qi, Mingbo Liu, Jianhui Li, Liwei Chen, Jiandong Zhao, Honghua Peng, Zhijian Xu, Yongxia Zhang, Xingyou Zhai, Liang Zong
Publikováno v:
Cell Biology International. 45:674-685
Laryngeal squamous cell carcinoma (LSCC) is the most common malignant tumor, which occurs in the head and neck. Current treatments for LSCC are all largely weakened by increasing drug resistance. Our study aimed to investigate the effects of long non
Autor:
Lingyun Wang, Guangcheng Chen, Yanshan Li, Hanqin Weng, Liang Chen, Tao Chen, Yunxiuxiu Xu, Linhui Cao, Yu Lai, Yibiao Ye
Publikováno v:
RNA Biol
Exosomes derived from human umbilical cord mesenchymal stem cells (hucMSCs) expressing microRNAs (miRNAs) have been highlighted in human cancers. However, the detailed molecular mechanism of hucMSCs-derived exosomal miR-451a on hepatocellular carcino
Autor:
Suoyi Huang, Pengya Wei, Zhongwei Zhang, Xueping Feng, Juan Xiao, Wei Liang, Bo Ling, Bingkui Cen, Guangbin Ye, Hong Wei, Songbo Li, Wei Huang
Publikováno v:
Oncology Reports
As a potential oncogene, nucleolar and spindle‑associated protein 1 (NUSAP1) is involved in the regulation of tumor cell proliferation, metastasis and drug resistance. However, the role of NUSAP1 in non‑small cell lung cancer (NSCLC) remains uncl