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Autor:
Ines Beilmann-Lehtonen, Ulf-Håkan Stenman, Caj Haglund, Tuomas Kaprio, Kajsa Björkman, Camilla Böckelman
Publikováno v:
Oncology. 100:22-30
Objectives: Colorectal cancer is the third most common cancer worldwide, with an obvious need for more accurate prognostics. Previous studies identified C-reactive protein (CRP) as a prognostic serum biomarker for colorectal cancer, whereas the bioma
Autor:
Pavel Fabian, Jaana Hagström, Tomas Jirasek, Caj Haglund, Richard Palmqvist, Tomáš Svoboda, Sofia Edin, Ioannis Gkekas, Tuomas Kaprio, Ulf Gunnarsson, Jan Novotny, Ines Beilmann-Lehtonen, Karin Strigård, Lucie Barsova
Publikováno v:
European Journal of Cancer. 157:1-9
Background The effect of the genetic imprint on the emergency presentation of colon cancer remains unclear. The disparity between tumours evolving along different carcinogenetic pathways has not been studied systematically. This retrospective multice
Autor:
Nikki van Leeuwen, Mengmeng Du, Iris Lansdorp-Vogelaar, Ann G. Zauber, Ewout W. Steyerberg, Elisabeth F. P. Peterse, Maaike Alblas
Publikováno v:
Cancer Medicine, Vol 10, Iss 19, Pp 6835-6844 (2021)
Cancer Medicine
Cancer Medicine, 10(19), 6835-6844. WILEY
Cancer Medicine, 10(19), 6835-6844. John Wiley & Sons Ltd.
Cancer Medicine
Cancer Medicine, 10(19), 6835-6844. WILEY
Cancer Medicine, 10(19), 6835-6844. John Wiley & Sons Ltd.
Background To evaluate the cost‐effectiveness of prophylactic hysterectomy (PH) in women with Lynch syndrome (LS). Methods We developed a microsimulation model incorporating the natural history for the development of hyperplasia with and without at
Autor:
David Sefrioui, Ludivine Beaussire, André Gillibert, France Blanchard, Emmanuel Toure, Céline Bazille, Anne Perdrix, Frédéric Ziegler, Alice Gangloff, Mélanie Hassine, Caroline Elie, Anne-Laure Bignon, Aurélie Parzy, Philippe Gomez, Caroline Thill, Florian Clatot, Jean-Christophe Sabourin, Thierry Frebourg, Jacques Benichou, Karine Bouhier-Leporrier, Marie-Pierre Gallais, Nasrin Sarafan-Vasseur, Pierre Michel, Frédéric Di Fiore
Publikováno v:
British Journal of Cancer
British Journal of Cancer, Cancer Research UK, 2021, ⟨10.1038/s41416-021-01431-9⟩
Br J Cancer
British Journal of Cancer, Cancer Research UK, 2021, ⟨10.1038/s41416-021-01431-9⟩
Br J Cancer
BACKGROUND: We previously reported that CEA kinetics are a marker of progressive disease (PD) in metastatic colorectal cancer (mCRC). This study was specifically designed to confirm CEA kinetics for predicting PD and to evaluate CA19-9, cell-free DNA
Autor:
Shaun Donovan, Russell Thomson, Joanne L. Dickinson, Janet L. Stanford, Georgea R. Foley, James R. Marthick, Liesel M. FitzGerald, Matthew A. Field, Roslyn C Malley, Annette Banks, Kelsie Raspin
Publikováno v:
International Journal of Cancer. 149:1089-1099
Prostate cancer (PrCa) is highly heritable, and although rare variants contribute significantly to PrCa risk, few have been identified to date. Herein, whole-genome sequencing was performed in a large PrCa family featuring multiple affected relatives
Autor:
Gilberto Fava, Marcus Matsushita, Cristovam Scapulatempo-Neto, Raphael Luiz Haikel Junior, Ernest T. Hawk, Maraisa Costa, Kelly Giardina, Leonardo Nogueira Taveira, Thais Talarico, Rui Manuel Reis, Carlos Augusto Rodrigues Véo, Denise Peixoto Guimarães, Larissa Andreoli Mantuan, Allini Mafra da Costa, José Humberto Tavares Guerreiro Fregnani, Marco Antonio de Oliveira, Edmundo Carvalho Mauad, Silvana Rossi
Publikováno v:
Cancer Prevention Research. 14:241-252
Colorectal cancer is the second most common cancer in Brazil. Yet, a nationally organized colorectal screening program is not implemented. Barretos Cancer Hospital (BCH) is one of the largest Brazilian institution that cares for underserved patients.
Autor:
Caj Haglund, Tuomas Kaprio, Jaana Hagström, Ines Beilmann-Lehtonen, Karin Strigård, Richard Palmqvist, Ulf-Håkan Stenman, Ulf Gunnarsson, Camilla Böckelman
Publikováno v:
Oncology. 99:790-801
Background: Colorectal cancer (CRC) is the third most commonly diagnosed malignancy globally. CRC patients with elevated plasma C-reactive protein (CRP) levels exhibit compromised prognoses. Toll-like receptors (TLRs), activating the innate and adapt
Publikováno v:
Epigenomics
Epigenomics, 2020, ⟨10.2217/epi-2020-0073⟩
Epigenomics, 2020, ⟨10.2217/epi-2020-0073⟩
Aim: We aim to identify driving genes of colorectal cancer (CRC) through multi-omics analysis. Materials & methods: We downloaded multi-omics data of CRC from The Cancer Genome Atlas dataset. Integrative analysis of single-nucleotide variants, copy n
Autor:
Caj Haglund, Kaisa Ahopelto, Jaana Hagström, Camilla Böckelman, Reetta Peltonen, Helena Isoniemi
Publikováno v:
Cancer Biology & Therapy
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Colorectal cancer (CRC) is the third most common cancer in the world. More than half of all affected patients develop liver metastases during the course of the disease, and over half experience recurrence despite radical primary surgery. Transketolas
Autor:
Wenwei Hu, Lanjing Zhang, Yong Lin, Zhaohui Feng, Meifang Zhang, Nan Gao, Jing-Ping Yun, Kun Hu
Publikováno v:
Cancer Causes Control
BackgroundThe recent staging manual upstages Node-negative tumor-deposit positive colorectal cancer (CRC) from N0 to N1c category, while the development of tumor-deposit presence is poorly understood. Meanwhile, Kras mutation is associated with progr