Zobrazeno 1 - 10
of 10
pro vyhledávání: '"STEINBERG, S"'
Autor:
Bigdeli, T. B, Ripke, S, Bacanu, Sa, Lee, S. H, Wray, Nr, Gejman, P. V, Rietschel, M, Cichon, S, St Clair, D, Corvin, A, Kirov, G, Mcquillin, A, Gurling, H, Rujescu, D, Andreassen, O. A, Werge, T, Blackwood, D. H. R, Pato, C. N, Pato, M. T, Malhotra, A. K, O'Donovan, M. C, Kendler, K. S, Fanous, A. H, Neale, Bm, Walters, Jt, Farh, Kh, Holmans, Pa, Lee, P, Bulik Sullivan, B, Collier, Da, Huang, H, Pers, Th, Agartz, I, Agerbo, E, Albus, M, Alexander, M, Amin, F, Begemann, M, Belliveau, Ra, Bene, J, Bergen, Se, Bevilacqua, E, Bigdeli, Tb, Black, Dw, Børglum, Ad, Bruggeman, R, Buccola, Ng, Buckner, Rl, Byerley, W, Cahn, W, Cai, G, Campion, D, Cantor, Rm, Carr, Vj, Carrera, N, Catts, Sv, Chambert, Kd, Chan, Rc, Chen, Ry, Chen, Ey, Cheng, W, Cheung, Ef, Chong, Sa, Cloninger, C, Cohen, D, Cohen, N, Cormican, P, Craddock, N, Crowley, Jj, Curtis, D, Davidson, M, Davis, Kl, Degenhardt, F, Del, Favero, J, Delisi, Le, Demontis, D, Dikeos, D, Dinan, T, Djurovic, S, Donohoe, G, Drapeau, E, Duan, J, Dudbridge, F, Durmishi, N, Eichhammer, P, Eriksson, J, Escott Price, V, Essioux, L, Fanous, Ah, Farrell, Ms, Frank, J, Franke, L, Freedman, R, Freimer, Nb, Friedl, M, Friedman, Ji, Fromer, M, Genovese, G, Georgieva, L, Gershon, Es, Giegling, I, Giusti Rodríguez, P, Godard, S, Goldstein, Ji, Golimbet, V, Gopal, S, Gratten, J, Grove, J, Haan, De, L, Hammer, C, Hamshere, Ml, Hansen, M, Hansen, T, Haroutunian, V, Hartmann, Am, Henskens, Fa, Herms, S, Hirschhorn, Jn, Hoffmann, P, Hofman, A, Hollegaard, Mv, Hougaard, Dm, Ikeda, M, Joa, I, Julìa, A, Kahn, Rs, Kalaydjieva, L, Karachanak Yankova, S, Karjalainen, J, Kavanagh, D, Keller, Mc, Kelly, Bj, Kennedy, Jl, Khrunin, A, Kim, Y, Klovins, J, Knowles, Ja, Konte, B, Kucinskas, V, Kucinskiene, Za, Kuzelova Ptackova, H, Kähler, Ak, Laurent, C, Keong, Jl, Lee, S, Legge, Se, Lerer, B, Li, M, Li, T, Liang, Ky, Lieberman, J, Limborska, S, Loughland, Cm, Lubinski, J, Lönnqvist, J, Macek, M, Magnusson, Pk, Maher, Bs, Maier, W, Mallet, J, Marsal, S, Mattheisen, M, Mattingsdal, M, Mccarley, Rw, Mcdonald, C, Mcintosh, Am, Meier, S, Meijer, Cj, Melegh, B, Melle, I, Mesholam Gately, Ri, Metspalu, A, Michie, Pt, Milani, L, Milanova, V, Mokrab, Y, Morris, Dw, Mors, O, Mortensen, Pb, Murphy, Kc, Murray, Rm, Myin Germeys, I, Müller Myhsok, B, Nelis, M, Nenadic, I, Nertney, Da, Nestadt, G, Nicodemus, Kk, Nikitina Zake, L, Nisenbaum, L, Nordin, A, O'Callaghan, E, O'Dushlaine, C, O'Neill, F, Sy, Oh, Olincy, A, Olsen, L, Jv, Os, Pantelis, C, Papadimitriou, Gn, Papiol, S, Parkhomenko, E, Pato, Mt, Paunio, T, Pejovic Milovancevic, M, Perkins, Do, Pietiläinen, O, Pimm, J, Pocklington, Aj, Powell, J, Price, A, Pulver, Ae, Purcell, Sm, Quested, D, Rasmussen, Hb, Reichenberg, A, Reimers, Ma, Richards, Al, Roffman, Jl, Roussos, P, Ruderfer, Dm, Salomaa, V, Sanders, Ar, Schall, U, Schubert, Cr, Schulze, Tg, Schwab, Sg, Scolnick, Em, Scott, Rj, Seidman, Lj, Shi, J, Sigurdsson, E, Silagadze, T, Silverman, Jm, Sim, K, Slominsky, P, Smoller, Jw, Hc, So, Spencer, Cc, Stahl, Ea, Stefansson, H, Steinberg, S, Stogmann, E, Straub, Re, Strengman, E, Strohmaier, J, Stroup, T, Subramaniam, M, Suvisaari, J, Svrakic, Dm, Szatkiewicz, Jp, Söderman, E, Thirumalai, S, Toncheva, D, Tooney, Pa, Tosato, Sarah, Veijola, J, Waddington, J, Walsh, D, Wang, D, Wang, Q, Webb, Bt, Weiser, M, Wildenauer, Db, Williams, Nm, Williams, S, Witt, Sh, Wolen, Ar, Wong, Eh, Wormley, Bk, Jq, Wu, Hs, Xi, Zai, Cc, Zheng, X, Zimprich, F, Stefansson, K, Visscher, Pm, Adolfsson, R, Andreassen, Oa, Blackwood, Dh, Bramon, E, Buxbaum, Jd, Darvasi, A, Domenici, E, Ehrenreich, H, Esko, T, Gejman, Pv, Gill, M, Hultman, Cm, Iwata, N, Jablensky, Av, Jönsson, Eg, Kendler, Ks, Knight, J, Lencz, T, Levinson, Df, Qs, Li, Liu, J, Malhotra, Ak, Mccarroll, Sa, Moran, Jl, Mowry, Bj, Nöthen, Mm, Ophoff, Ra, Owen, Mj, Palotie, A, Pato, Cn, Petryshen, Tl, Posthuma, D, Riley, Bp, Sham, Pc, Sklar, P, Clair, Ds, Weinberger, Dr, Wendland, Jr, Daly, Mj, Sullivan, Pf, O'Donovan, Mc
Publikováno v:
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 276-289. Wiley-Liss Inc.
ISSUE=171B;STARTPAGE=276;ENDPAGE=289;ISSN=1552-4841;TITLE=American Journal of Medical Genetics Part B: Neuropsychiatric Genetics
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics
American journal of medical genetics. Part B, Neuropsychiatric genetics, 171BB(2), 276-289. Wiley-Liss Inc.
Bigdeli, T B, Ripke, S, Bacanu, S A, Lee, S H, Schizophrenia Working Group of the Psychiatric Genomics, U & Posthuma, D 2016, ' Genome-wide association study reveals greater polygenic loading for schizophrenia in cases with a family history of illness. ', American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, no. 171B, 2, pp. 276-289 . https://doi.org/10.1002/ajmg.b.32402
American Journal of Medical Genetics Part B-neuropsychiatric Genetics, 171(2), 276-289. Wiley
American journal of medical genetics: part B: neuropsychiatric genetics
ISSUE=171B;STARTPAGE=276;ENDPAGE=289;ISSN=1552-4841;TITLE=American Journal of Medical Genetics Part B: Neuropsychiatric Genetics
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics
American journal of medical genetics. Part B, Neuropsychiatric genetics, 171BB(2), 276-289. Wiley-Liss Inc.
Bigdeli, T B, Ripke, S, Bacanu, S A, Lee, S H, Schizophrenia Working Group of the Psychiatric Genomics, U & Posthuma, D 2016, ' Genome-wide association study reveals greater polygenic loading for schizophrenia in cases with a family history of illness. ', American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, no. 171B, 2, pp. 276-289 . https://doi.org/10.1002/ajmg.b.32402
American Journal of Medical Genetics Part B-neuropsychiatric Genetics, 171(2), 276-289. Wiley
American journal of medical genetics: part B: neuropsychiatric genetics
Genome-wide association studies (GWAS) of schizophrenia have yielded more than 100 common susceptibility variants, and strongly support a substantial polygenic contribution of a large number of small allelic effects. It has been hypothesized that fam
Autor:
Maier, R. M., Zhu, Z., Lee, S. H., Trzaskowski, M., Ruderfer, D. M., Stahl, E. A., Ripke, S., Wray, N. R., Yang, J., Visscher, P. M., Robinson, M. R., Forstner, A. J., Mcquillin, A., Trubetskoy, V., Wang, W., Wang, Y., Coleman, J. R. I., Gaspar, H. A., Leeuw, C. A., Whitehead Pavlides, J. M., Olde Loohuis, L. M., Pers, T. H., Lee, P. H., Charney, A. W., Dobbyn, A. L., Huckins, L., Boocock, J., Giambartolomei, C., Roussos, P., Mullins, N., Awasthi, S., Agerbo, E., Als, T. D., Pedersen, C. B., Grove, J., Kupka, R., Regeer, E. J., Anjorin, A., Casas, M., Mahon, P. B., Allardyce, J., Escott-Price, V., Forty, L., Fraser, C., Kogevinas, M., Frank, J., Streit, F., Strohmaier, J., Treutlein, J., Witt, S. H., Kennedy, J. L., Strauss, J. S., Garnham, J., O Donovan, C., Slaney, C., Steinberg, S., Thorgeirsson, T. E., Hautzinger, M., Steffens, M., Perlis, R. H., Sánchez-Mora, C., Hipolito, M., Lawson, W. B., Nwulia, E. A., Levy, S. E., Foroud, T. M., Jamain, S., Young, A. H., Mckay, J. D., Albani, D., Zandi, P., Potash, J. B., Zhang, P., Raymond Depaulo, J., Bergen, S. E., Juréus, A., Karlsson, R., Kandaswamy, R., Mcguffin, P., Rivera, M., Lissowska, J., Cruceanu, C., Lucae, S., Cervantes, P., Budde, M., Gade, K., Heilbronner, U., Pedersen, M. G., Morris, D. W., Weickert, C. S., Weickert, T. W., Macintyre, D. J., Lawrence, J., Elvsåshagen, T., Smeland, O. B., Djurovic, S., Xi, S., Green, E. K., Czerski, P. M., Hauser, J., Xu, W., Vedder, H., Oruc, L., Spijker, A. T., Gordon, S. D., Medland, S. E., Curtis, D., Mühleisen, T. W., Badner, J. A., Scheftner, W. A., Sigurdsson, E., Schork, N. J., Schatzberg, A. F., Bækvad-Hansen, M., Bybjerg-Grauholm, J., Hansen, C. S., Knowles, J. A., Szelinger, S., Montgomery, G. W., Boks, M., Adolfsson, A. N., Hoffmann, P., Bauer, M., Pfennig, A., Leber, M., Kittel-Schneider, S., Reif, A., Del-Favero, J., Fischer, S. B., Herms, S., Reinbold, C. S., Degenhardt, F., Koller, A. C., Maaser, A., Ori, A. P. S., Dale, A. M., Fan, C. C., Greenwood, T. A., Nievergelt, C. M., Shehktman, T., Shilling, P. D., Byerley, W., Bunney, W., Alliey-Rodriguez, N., Clarke, T. K., Liu, C., Coryell, W., Akil, H., Burmeister, M., Flickinger, M., Li, J. Z., Mcinnis, M. G., Meng, F., Thompson, R. C., Watson, S. J., Zollner, S., Guan, W., Green, M. J., Craig, D., Sobell, J. L., Milani, L., Gordon-Smith, Katherine, Knott, Sarah, Perry, Amy, Parra, J. G., Mayoral, F., Rivas, F., Rice, J. P., Barchas, J. D., Børglum, A. D., Mortensen, P. B., Mors, O., Grigoroiu-Serbanescu, M., Bellivier, F., Etain, B., Leboyer, M., Ramos-Quiroga, J. A., Agartz, I., Amin, F., Azevedo, M. H., Bass, N., Black, D. W., Blackwood, D. H. R., Bruggeman, R., Buccola, N. G., Choudhury, K., Cloninger, C. R., Corvin, A., Craddock, N., Daly, M. J., Datta, S., Donohoe, G. J., Duan, J., Dudbridge, F., Fanous, A., Freedman, R., Freimer, N. B., Friedl, M., Gill, M., Gurling, H., Haan, L., Hamshere, M. L., Hartmann, A. M., Holmans, P. A., Kahn, R. S., Keller, M. C., Kenny, E., Kirov, G. K., Krabbendam, L., Krasucki, R., Lencz, T., Levinson, D. F., Lieberman, J. A., Lin, D. -Y, Linszen, D. H., Magnusson, P. K. E., Maier, W., Malhotra, A. K., Mattheisen, M., Mattingsdal, M., Mccarroll, S. A., Medeiros, H., Melle, I., Milanova, V., Myin-Germeys, I., Neale, B. M., Ophoff, R. A., Owen, M. J., Pimm, J., Purcell, S. M., Puri, V., Digby Quested, Rossin, L., Sanders, A. R., Shi, J., Sklar, P., St Clair, D., Stroup, T. S., Os, J., Wiersma, D., Zammit, S.
Publikováno v:
Nature Communications
Nature Communications, 9(1):02769-6. Nature Publishing Group
Maier, R M, Zhu, Z, Lee, S H, Trzaskowski, M, Ruderfer, D M, Stahl, E A, Ripke, S, Wray, N R, Yang, J, Visscher, P M, Robinson, M R, Forstner, A J, Mcquillin, A, Trubetskoy, V, Wang, W, Wang, Y, Coleman, J R I, Gaspar, H A, De Leeuw, C A, Whitehead Pavlides, J M, Olde Loohuis, L M, Pers, T H, Lee, P H, Charney, A W, Dobbyn, A L, Huckins, L, Boocock, J, Giambartolomei, C, Roussos, P, Mullins, N, Awasthi, S, Agerbo, E, Als, T D, Pedersen, C B, Grove, J, Kupka, R, Regeer, E J, Anjorin, A, Casas, M, Mahon, P B, Allardyce, J, Escott-Price, V, Forty, L, Fraser, C, Kogevinas, M, Frank, J, Streit, F, Strohmaier, J & Treutlein, J 2018, ' Improving genetic prediction by leveraging genetic correlations among human diseases and traits ', Nature Communications, vol. 9, no. 1, 02769-6 . https://doi.org/10.1038/s41467-017-02769-6
Nature Communications, 9(1). Nature Publishing Group
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Nature communications, 9(1):02769-6. Nature Publishing Group
Maier, R M, Zhu, Z, Lee, S H, Trzaskowski, M, Ruderfer, D M, Stahl, E A, Ripke, S, Wray, N R, Yang, J, Visscher, P M, Robinson, M R, Forstner, A J, Mcquillin, A, Trubetskoy, V, Wang, W, Wang, Y, Coleman, J R I, Gaspar, H L A, de Leeuw, C A, Whitehead Pavlides, J M, Olde Loohuis, L M, Pers, T H, Lee, P H, Charney, A W, Dobbyn, A L, Huckins, L, Boocock, J, Giambartolomei, C, Roussos, P, Mullins, N, Awasthi, S, Agerbo, E, Als, T D, Pedersen, C B C, Grove, J, Kupka, R, Regeer, E J, Anjorin, A, Casas, M, Mahon, P B, Allardyce, J, Escott-Price, V, Forty, L, Fraser, C, Kogevinas, M, Frank, J, Streit, F, Strohmaier, J, Treutlein, J, Witt, S H, Kennedy, J L, Strauss, J S, Garnham, J, O'donovan, C, Slaney, C, Steinberg, S, Thorgeirsson, T E, Hautzinger, M, Steffens, M, Perlis, R H, Sánchez-Mora, C, Hipolito, M, Lawson, W B, Nwulia, E A, Levy, S E, Foroud, T M, Jamain, S, Young, A H, Mckay, J D, Albani, D, Zandi, P, Potash, J B, Zhang, P, Raymond Depaulo, J, Bergen, S E, Juréus, A, Karlsson, R, Kandaswamy, R, Mcguffin, P, Rivera, M, Lissowska, J, Cruceanu, C, Lucae, S, Cervantes, P, Budde, M, Gade, K, Heilbronner, U, Pedersen, M G, Morris, D W, Weickert, C S, Weickert, T W, Macintyre, D J, Lawrence, J, Elvsåshagen, T, Smeland, O B, Djurovic, S, Xi, S, Green, E K, Czerski, P M, Hauser, J, Xu, W, Vedder, H, Oruc, L, Spijker, A T, Gordon, S D, Medland, S E, Curtis, D, Mühleisen, T W, Badner, J, Scheftner, W A, Sigurdsson, E, Schork, N J, Schatzberg, A F, Bækvad-Hansen, M, Bybjerg-Grauholm, J, Hansen, C S H, Knowles, J A, Szelinger, S, Montgomery, G W, Boks, M, Adolfsson, A N, Hoffmann, P, Bauer, M, Pfennig, A, Leber, M, Kittel-Schneider, S, Reif, A, del-Favero, J, Fischer, S B, Herms, S, Reinbold, C L S, Degenhardt, F, Koller, A C, Maaser, A, Ori, A, Dale, A M, Fan, C C, Greenwood, T A, Nievergelt, C M, Shehktman, T, Shilling, P D, Byerley, W, Bunney, W, Alliey-Rodriguez, N, Clarke, T-K, Liu, C, Coryell, W, Akil, H, Burmeister, M, Flickinger, M, Li, J Z, Mcinnis, M G, Meng, F, Thompson, R C, Watson, S J, Zollner, S, Guan, W, Green, M J, Craig, D, Sobell, J L, Milani, L, Gordon-Smith, K, Knott, S V, Perry, A, Parra, J G, Mayoral, F, Rivas, F, Rice, J P, Barchas, J D, Børglum, A D, Mortensen, P B, Mors, O, Grigoroiu-Serbanescu, M, Bellivier, F, Etain, B, Leboyer, M, Ramos-Quiroga, J A, Agartz, I, Amin, F, Azevedo, M H, Bass, N, Black, D W, Blackwood, D H R, Bruggeman, R, Buccola, N G, Choudhury, K, Cloninger, C R, Corvin, A, Craddock, N, Daly, M J, Datta, S, Donohoe, G J, Duan, J, Dudbridge, F, Fanous, A, Freedman, R, Freimer, N B, Friedl, M, Gill, M, Gurling, H, de Haan, L, Hamshere, M L, Hartmann, A M, Holmans, P A, Kahn, R S, Keller, M C, Kenny, E, Kirov, G K, Krabbendam, L, Krasucki, R, Lencz, T, Levinson, D F, Lieberman, J A, Lin, D-Y, Linszen, D H, Magnusson, P K E, Maier, W, Malhotra, A K, Mattheisen, M, Mattingsdal, M, Mccarroll, S A, Medeiros, H, Melle, I, Milanova, V, Myin-Germeys, I, Neale, B M, Ophoff, R A, Owen, M J, Pimm, J, Purcell, S M, Puri, V, Quested, D J, Rossin, L, Sanders, A R, Shi, J, Sklar, P, St Clair, D, Stroup, T S, van Os, J, Wiersma, D & Zammit, S 2018, ' Improving genetic prediction by leveraging genetic correlations among human diseases and traits ', Nature Communications, vol. 9, no. 1, 02769-6 . https://doi.org/10.1038/s41467-017-02769-6
Nature communications, vol. 9, no. 1, pp. 989
Maier, R M, Zhu, Z, Lee, S H, Trzaskowski, M, Ruderfer, D M, Stahl, E A, Ripke, S, Wray, N R, Yang, J & Visscher, P M & Robinson, M R 2018, ' Improving genetic prediction by leveraging genetic correlations among human diseases and traits ', Nature Communications, vol. 9, no. 1, 989 . https://doi.org/10.1038/s41467-017-02769-6
Maier, R M, Zhu, Z, Lee, S H, Trzaskowski, M, Ruderfer, D M, Stahl, E A, Ripke, S, Wray, N R, Yang, J, Visscher, P M, Robinson, M R, Forstner, A J, Mcquillin, A, Trubetskoy, V, Wang, W, Wang, Y, Coleman, J R I, Gaspar, H A, De Leeuw, C A, Whitehead Pavlides, J M, Olde Loohuis, L M, Pers, T H, Lee, P H, Charney, A W, Dobbyn, A L, Huckins, L, Boocock, J, Giambartolomei, C, Roussos, P, Mullins, N, Awasthi, S, Agerbo, E, Als, T D, Pedersen, C B, Grove, J, Kupka, R, Regeer, E J, Anjorin, A, Casas, M, Mahon, P B, Allardyce, J, Escott-Price, V, Forty, L, Fraser, C, Kogevinas, M, Frank, J, Streit, F, Strohmaier, J, Treutlein, J, Witt, S H, Kennedy, J L, Strauss, J S, Garnham, J, O'donovan, C, Slaney, C, Steinberg, S, Thorgeirsson, T E, Hautzinger, M, Steffens, M, Perlis, R H, Sánchez-Mora, C, Hipolito, M, Lawson, W B, Nwulia, E A, Levy, S E, Foroud, T M, Jamain, S, Young, A H, Mckay, J D, Albani, D, Zandi, P, Potash, J B, Zhang, P, Raymond Depaulo, J, Bergen, S E, Juréus, A, Karlsson, R, Kandaswamy, R, Mcguffin, P, Rivera, M, Lissowska, J, Cruceanu, C, Lucae, S, Cervantes, P, Budde, M, Gade, K, Heilbronner, U, Pedersen, M G, Morris, D W, Weickert, C S, Weickert, T W, Macintyre, D J, Lawrence, J, Elvsåshagen, T, Smeland, O B, Djurovic, S, Xi, S, Green, E K, Czerski, P M, Hauser, J, Xu, W, Vedder, H, Oruc, L, Spijker, A T, Gordon, S D, Medland, S E, Curtis, D, Mühleisen, T W, Badner, J, Scheftner, W A, Sigurdsson, E, Schork, N J, Schatzberg, A F, Bækvad-Hansen, M, Bybjerg-Grauholm, J, Hansen, C S, Knowles, J A, Szelinger, S, Montgomery, G W, Boks, M, Adolfsson, A N, Hoffmann, P, Bauer, M, Pfennig, A, Leber, M, Kittel-Schneider, S, Reif, A, Del-Favero, J, Fischer, S B, Herms, S, Reinbold, C S, Degenhardt, F, Koller, A C, Maaser, A, Ori, A, Dale, A M, Fan, C C, Greenwood, T A, Nievergelt, C M, Shehktman, T, Shilling, P D, Byerley, W, Bunney, W, Alliey-Rodriguez, N, Clarke, T K, Liu, C, Coryell, W, Akil, H, Burmeister, M, Flickinger, M, Li, J Z, Mcinnis, M G, Meng, F, Thompson, R C, Watson, S J, Zollner, S, Guan, W, Green, M J, Craig, D, Sobell, J L, Milani, L, Gordon-Smith, K, Knott, S V, Perry, A, Parra, J G, Mayoral, F, Rivas, F, Rice, J P, Barchas, J D, Børglum, A D, Mortensen, P B, Mors, O, Grigoroiu-Serbanescu, M, Bellivier, F, Etain, B, Leboyer, M, Ramos-Quiroga, J A, Agartz, I, Amin, F, Azevedo, M H, Bass, N, Black, D W, Blackwood, D H R, Bruggeman, R, Buccola, N G, Choudhury, K, Cloninger, C R, Corvin, A, Craddock, N, Daly, M J, Datta, S, Donohoe, G J, Duan, J, Dudbridge, F, Fanous, A, Freedman, R, Freimer, N B, Friedl, M, Gill, M, Gurling, H, De Haan, L, Hamshere, M L, Hartmann, A M, Holmans, P A, Kahn, R S, Keller, M C, Kenny, E, Kirov, G K, Krabbendam, L, Krasucki, R, Lencz, T, Levinson, D F, Lieberman, J A, Lin, D Y, Linszen, D H, Magnusson, P K E, Maier, W, Malhotra, A K, Mattheisen, M, Mattingsdal, M, Mccarroll, S A, Medeiros, H, Melle, I, Milanova, V, Myin-Germeys, I, Neale, B M, Ophoff, R A, Owen, M J, Pimm, J, Purcell, S M, Puri, V, Quested, D J, Rossin, L, Sanders, A R, Shi, J, Sklar, P, St Clair, D, Stroup, T S, Van Os, J, Wiersma, D & Zammit, S 2018, ' Improving genetic prediction by leveraging genetic correlations among human diseases and traits ', Nature Communications, vol. 9, no. 1, 02769-6 . https://doi.org/10.1038/s41467-017-02769-6
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Nature Communications, 9(1):02769-6. Nature Publishing Group
Maier, R M, Zhu, Z, Lee, S H, Trzaskowski, M, Ruderfer, D M, Stahl, E A, Ripke, S, Wray, N R, Yang, J, Visscher, P M, Robinson, M R, Forstner, A J, Mcquillin, A, Trubetskoy, V, Wang, W, Wang, Y, Coleman, J R I, Gaspar, H A, De Leeuw, C A, Whitehead Pavlides, J M, Olde Loohuis, L M, Pers, T H, Lee, P H, Charney, A W, Dobbyn, A L, Huckins, L, Boocock, J, Giambartolomei, C, Roussos, P, Mullins, N, Awasthi, S, Agerbo, E, Als, T D, Pedersen, C B, Grove, J, Kupka, R, Regeer, E J, Anjorin, A, Casas, M, Mahon, P B, Allardyce, J, Escott-Price, V, Forty, L, Fraser, C, Kogevinas, M, Frank, J, Streit, F, Strohmaier, J & Treutlein, J 2018, ' Improving genetic prediction by leveraging genetic correlations among human diseases and traits ', Nature Communications, vol. 9, no. 1, 02769-6 . https://doi.org/10.1038/s41467-017-02769-6
Nature Communications, 9(1). Nature Publishing Group
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Nature communications, 9(1):02769-6. Nature Publishing Group
Maier, R M, Zhu, Z, Lee, S H, Trzaskowski, M, Ruderfer, D M, Stahl, E A, Ripke, S, Wray, N R, Yang, J, Visscher, P M, Robinson, M R, Forstner, A J, Mcquillin, A, Trubetskoy, V, Wang, W, Wang, Y, Coleman, J R I, Gaspar, H L A, de Leeuw, C A, Whitehead Pavlides, J M, Olde Loohuis, L M, Pers, T H, Lee, P H, Charney, A W, Dobbyn, A L, Huckins, L, Boocock, J, Giambartolomei, C, Roussos, P, Mullins, N, Awasthi, S, Agerbo, E, Als, T D, Pedersen, C B C, Grove, J, Kupka, R, Regeer, E J, Anjorin, A, Casas, M, Mahon, P B, Allardyce, J, Escott-Price, V, Forty, L, Fraser, C, Kogevinas, M, Frank, J, Streit, F, Strohmaier, J, Treutlein, J, Witt, S H, Kennedy, J L, Strauss, J S, Garnham, J, O'donovan, C, Slaney, C, Steinberg, S, Thorgeirsson, T E, Hautzinger, M, Steffens, M, Perlis, R H, Sánchez-Mora, C, Hipolito, M, Lawson, W B, Nwulia, E A, Levy, S E, Foroud, T M, Jamain, S, Young, A H, Mckay, J D, Albani, D, Zandi, P, Potash, J B, Zhang, P, Raymond Depaulo, J, Bergen, S E, Juréus, A, Karlsson, R, Kandaswamy, R, Mcguffin, P, Rivera, M, Lissowska, J, Cruceanu, C, Lucae, S, Cervantes, P, Budde, M, Gade, K, Heilbronner, U, Pedersen, M G, Morris, D W, Weickert, C S, Weickert, T W, Macintyre, D J, Lawrence, J, Elvsåshagen, T, Smeland, O B, Djurovic, S, Xi, S, Green, E K, Czerski, P M, Hauser, J, Xu, W, Vedder, H, Oruc, L, Spijker, A T, Gordon, S D, Medland, S E, Curtis, D, Mühleisen, T W, Badner, J, Scheftner, W A, Sigurdsson, E, Schork, N J, Schatzberg, A F, Bækvad-Hansen, M, Bybjerg-Grauholm, J, Hansen, C S H, Knowles, J A, Szelinger, S, Montgomery, G W, Boks, M, Adolfsson, A N, Hoffmann, P, Bauer, M, Pfennig, A, Leber, M, Kittel-Schneider, S, Reif, A, del-Favero, J, Fischer, S B, Herms, S, Reinbold, C L S, Degenhardt, F, Koller, A C, Maaser, A, Ori, A, Dale, A M, Fan, C C, Greenwood, T A, Nievergelt, C M, Shehktman, T, Shilling, P D, Byerley, W, Bunney, W, Alliey-Rodriguez, N, Clarke, T-K, Liu, C, Coryell, W, Akil, H, Burmeister, M, Flickinger, M, Li, J Z, Mcinnis, M G, Meng, F, Thompson, R C, Watson, S J, Zollner, S, Guan, W, Green, M J, Craig, D, Sobell, J L, Milani, L, Gordon-Smith, K, Knott, S V, Perry, A, Parra, J G, Mayoral, F, Rivas, F, Rice, J P, Barchas, J D, Børglum, A D, Mortensen, P B, Mors, O, Grigoroiu-Serbanescu, M, Bellivier, F, Etain, B, Leboyer, M, Ramos-Quiroga, J A, Agartz, I, Amin, F, Azevedo, M H, Bass, N, Black, D W, Blackwood, D H R, Bruggeman, R, Buccola, N G, Choudhury, K, Cloninger, C R, Corvin, A, Craddock, N, Daly, M J, Datta, S, Donohoe, G J, Duan, J, Dudbridge, F, Fanous, A, Freedman, R, Freimer, N B, Friedl, M, Gill, M, Gurling, H, de Haan, L, Hamshere, M L, Hartmann, A M, Holmans, P A, Kahn, R S, Keller, M C, Kenny, E, Kirov, G K, Krabbendam, L, Krasucki, R, Lencz, T, Levinson, D F, Lieberman, J A, Lin, D-Y, Linszen, D H, Magnusson, P K E, Maier, W, Malhotra, A K, Mattheisen, M, Mattingsdal, M, Mccarroll, S A, Medeiros, H, Melle, I, Milanova, V, Myin-Germeys, I, Neale, B M, Ophoff, R A, Owen, M J, Pimm, J, Purcell, S M, Puri, V, Quested, D J, Rossin, L, Sanders, A R, Shi, J, Sklar, P, St Clair, D, Stroup, T S, van Os, J, Wiersma, D & Zammit, S 2018, ' Improving genetic prediction by leveraging genetic correlations among human diseases and traits ', Nature Communications, vol. 9, no. 1, 02769-6 . https://doi.org/10.1038/s41467-017-02769-6
Nature communications, vol. 9, no. 1, pp. 989
Maier, R M, Zhu, Z, Lee, S H, Trzaskowski, M, Ruderfer, D M, Stahl, E A, Ripke, S, Wray, N R, Yang, J & Visscher, P M & Robinson, M R 2018, ' Improving genetic prediction by leveraging genetic correlations among human diseases and traits ', Nature Communications, vol. 9, no. 1, 989 . https://doi.org/10.1038/s41467-017-02769-6
Maier, R M, Zhu, Z, Lee, S H, Trzaskowski, M, Ruderfer, D M, Stahl, E A, Ripke, S, Wray, N R, Yang, J, Visscher, P M, Robinson, M R, Forstner, A J, Mcquillin, A, Trubetskoy, V, Wang, W, Wang, Y, Coleman, J R I, Gaspar, H A, De Leeuw, C A, Whitehead Pavlides, J M, Olde Loohuis, L M, Pers, T H, Lee, P H, Charney, A W, Dobbyn, A L, Huckins, L, Boocock, J, Giambartolomei, C, Roussos, P, Mullins, N, Awasthi, S, Agerbo, E, Als, T D, Pedersen, C B, Grove, J, Kupka, R, Regeer, E J, Anjorin, A, Casas, M, Mahon, P B, Allardyce, J, Escott-Price, V, Forty, L, Fraser, C, Kogevinas, M, Frank, J, Streit, F, Strohmaier, J, Treutlein, J, Witt, S H, Kennedy, J L, Strauss, J S, Garnham, J, O'donovan, C, Slaney, C, Steinberg, S, Thorgeirsson, T E, Hautzinger, M, Steffens, M, Perlis, R H, Sánchez-Mora, C, Hipolito, M, Lawson, W B, Nwulia, E A, Levy, S E, Foroud, T M, Jamain, S, Young, A H, Mckay, J D, Albani, D, Zandi, P, Potash, J B, Zhang, P, Raymond Depaulo, J, Bergen, S E, Juréus, A, Karlsson, R, Kandaswamy, R, Mcguffin, P, Rivera, M, Lissowska, J, Cruceanu, C, Lucae, S, Cervantes, P, Budde, M, Gade, K, Heilbronner, U, Pedersen, M G, Morris, D W, Weickert, C S, Weickert, T W, Macintyre, D J, Lawrence, J, Elvsåshagen, T, Smeland, O B, Djurovic, S, Xi, S, Green, E K, Czerski, P M, Hauser, J, Xu, W, Vedder, H, Oruc, L, Spijker, A T, Gordon, S D, Medland, S E, Curtis, D, Mühleisen, T W, Badner, J, Scheftner, W A, Sigurdsson, E, Schork, N J, Schatzberg, A F, Bækvad-Hansen, M, Bybjerg-Grauholm, J, Hansen, C S, Knowles, J A, Szelinger, S, Montgomery, G W, Boks, M, Adolfsson, A N, Hoffmann, P, Bauer, M, Pfennig, A, Leber, M, Kittel-Schneider, S, Reif, A, Del-Favero, J, Fischer, S B, Herms, S, Reinbold, C S, Degenhardt, F, Koller, A C, Maaser, A, Ori, A, Dale, A M, Fan, C C, Greenwood, T A, Nievergelt, C M, Shehktman, T, Shilling, P D, Byerley, W, Bunney, W, Alliey-Rodriguez, N, Clarke, T K, Liu, C, Coryell, W, Akil, H, Burmeister, M, Flickinger, M, Li, J Z, Mcinnis, M G, Meng, F, Thompson, R C, Watson, S J, Zollner, S, Guan, W, Green, M J, Craig, D, Sobell, J L, Milani, L, Gordon-Smith, K, Knott, S V, Perry, A, Parra, J G, Mayoral, F, Rivas, F, Rice, J P, Barchas, J D, Børglum, A D, Mortensen, P B, Mors, O, Grigoroiu-Serbanescu, M, Bellivier, F, Etain, B, Leboyer, M, Ramos-Quiroga, J A, Agartz, I, Amin, F, Azevedo, M H, Bass, N, Black, D W, Blackwood, D H R, Bruggeman, R, Buccola, N G, Choudhury, K, Cloninger, C R, Corvin, A, Craddock, N, Daly, M J, Datta, S, Donohoe, G J, Duan, J, Dudbridge, F, Fanous, A, Freedman, R, Freimer, N B, Friedl, M, Gill, M, Gurling, H, De Haan, L, Hamshere, M L, Hartmann, A M, Holmans, P A, Kahn, R S, Keller, M C, Kenny, E, Kirov, G K, Krabbendam, L, Krasucki, R, Lencz, T, Levinson, D F, Lieberman, J A, Lin, D Y, Linszen, D H, Magnusson, P K E, Maier, W, Malhotra, A K, Mattheisen, M, Mattingsdal, M, Mccarroll, S A, Medeiros, H, Melle, I, Milanova, V, Myin-Germeys, I, Neale, B M, Ophoff, R A, Owen, M J, Pimm, J, Purcell, S M, Puri, V, Quested, D J, Rossin, L, Sanders, A R, Shi, J, Sklar, P, St Clair, D, Stroup, T S, Van Os, J, Wiersma, D & Zammit, S 2018, ' Improving genetic prediction by leveraging genetic correlations among human diseases and traits ', Nature Communications, vol. 9, no. 1, 02769-6 . https://doi.org/10.1038/s41467-017-02769-6
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Genomic prediction has the potential to contribute to precision medicine. However, to date, the utility of such predictors is limited due to low accuracy for most traits. Here theory and simulation study are used to demonstrate that widespread pleiot
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Pan, H, Gray, R, Braybrooke, J, Davies, C, Taylor, C, Mcgale, P, Peto, R, Pritchard, Ki, Bergh, J, Dowsett, M, Hayes, Df, Albain, K, Anderson, S, Arriagada, R, Barlow, W, Bartlett, J, Bergsten‐nordström, E, Bliss, J, Boccardo, F, Bradley, R, Brain, E, Cameron, D, Clarke, M, Coates, A, Coleman, R, Correa, C, Costantino, J, Cuzick, J, Davidson, N, Dodwell, D, Di Leo, A, Ewertz, M, Forbes, J, Gelber, R, Gnant, M, Goldhirsch, A, Goodwin, P, Hill, C, Ingle, J, Jagsi, R, Janni, W, Loibl, S, Mackinnon, E, Martin, M, Mukai, H, Norton, L, Ohashi, Y, Paik, S, Perez, E, Piccart, M, Pierce, L, Poortmans, P, Raina, V, Ravdin, P, Regan, M, Robertson, J, Rutgers, E, Slamon, D, Sparano, J, Swain, S, Tutt, A, Viale, G, Von Minckwitz, G, Wang, X, Whelan, T, Wilcken, N, Winer, E, Wolmark, N, Wood, W, Zambetti, M, Alberro, Ja, Ballester, B, Deulofeu, P, Fábregas, R, Fraile, M, Gubern, Jm, Janer, J, Moral, A, De Pablo Jl, Peñalva, G, Puig, P, Ramos, M, Rojo, R, Santesteban, P, Serra, C, Solà, M, Solarnau, L, Solsona, J, Veloso, E, Vidal, S, Abe, O, Abe, R, Enomoto, K, Kikuchi, K, Koyama, H, Masuda, H, Nomura, Y, Sakai, K, Sugimachi, K, Toi, M, Tominaga, T, Uchino, J, Yoshida, M, Haybittle, Jl, Leonard, Cf, Calais, G, Garaud, P, Collett, V, Delmestri, A, Sayer, J, Harvey, Vj, Holdaway, Im, Kay, Rg, Mason, Bh, Forbes, Jf, Balic, M, Bartsch, R, Fesl, C, Fitzal, F, Fohler, H, Greil, R, Jakesz, R, Marth, C, Mlineritsch, B, Pfeiler, G, Singer, Cf, Steger, Gg, Stöger, H, Canney, P, Yosef, Hma, Focan, C, Peek, U, Oates, Gd, Powell, J, Durand, M, Mauriac, L, Dolci, S, Larsimont, D, Nogaret, Jm, Philippson, C, Piccart, Mj, Masood, Mb, Parker, D, Price, Jj, Lindsay, Ma, Mackey, J, Hupperets, Psgj, Bates, T, Blamey, Rw, Chetty, U, Ellis, Io, Mallon, E, Morgan, Dal, Patnick, J, Pinder, S, Lohrisch, C, Nichol, A, Bramwell, Vh, Chen, Be, Gelmon, K, Goss, Pe, Levine, Mn, Parulekar, W, Pater, Jl, Shepherd, Le, Tu, D, Berry, D, Broadwater, G, Cirrincione, C, Muss, H, Weiss, Rb, Abu‐zahra, Ht, Portnoj, Sm, Bowden, S, Brookes, C, Dunn, J, Fernando, I, Lee, M, Poole, C, Rea, D, Spooner, D, Barrett‐lee, Pj, Mansel, Re, Monypenny, Ij, Gordon, Nh, Davis, Hl, Sestak, I, Lehingue, Y, Romestaing, P, Dubois, Jb, Delozier, T, Griffon, B, Mace Lesec’h, J, De La Lande, B, Mouret‐fourme, E, Mustacchi, G, Petruzelka, L, Pribylova, O, Owen, Jr, Harbeck, N, Jänicke, F, Meisner, C, Schmitt, M, Thomssen, C, Meier, P, Shan, Y, Shao, Yf, Zhao, Db, Chen, Zm, Howell, A, Swindell, R, Boddington, C, Burrett, Ja, Cutter, D, Duane, F, Evans, V, Gettins, L, Godwin, J, James, S, Kerr, A, Liu, H, Mannu, G, Mchugh, T, Morris, P, Read, S, Wang, Y, Wang, Z, Albano, J, De Oliveira Cf, Gervásio, H, Gordilho, J, Ejlertsen, B, Jensen, Mb, Johansen, H, Mouridsen, H, Palshof, T, Gelman, Rs, Harris, Jr, Henderson, C, Shapiro, Cl, Christiansen, P, Mouridsen, Ht, Fehm, T, Trampisch, Hj, Dalesio, O, De Vries Ege, Rodenhuis, S, Van Tinteren, H, Comis, Rl, Davidson, Ne, Robert, N, Sledge, G, Solin, Lj, Sparano, Ja, Tormey, Dc, Dixon, Jm, Forrest, P, Jack, W, Kunkler, I, Rossbach, J, Klijn, Jgm, Treurniet‐donker, Ad, Van Putten Wlj, Rotmensz, N, Veronesi, U, Bartelink, H, Bijker, N, Bogaerts, J, Cardoso, F, Cufer, T, Julien, Jp, Van De Velde Cjh, Cunningham, Mp, Brufsky, Am, Coleman, Re, Llombart, Ha, Huovinen, R, Joensuu, H, Costa, A, Bonadonna, G, Gianni, L, Valagussa, P, Goldstein, Lj, Bonneterre, J, Fargeot, P, Fumoleau, P, Kerbrat, P, Luporsi, E, Namer, M, Carrasco, E, Segui, Ma, Eiermann, W, Hilfrich, J, Jonat, W, Kaufmann, M, Kreienberg, R, Schumacher, M, Bastert, G, Rauschecker, H, Sauer, R, Sauerbrei, W, Schauer, A, Blohmer, Ju, Costa, Sd, Eidtmann, H, Gerber, B, Jackisch, C, De Schryver, A, Vakaet, L, Belfiglio, M, Nicolucci, A, Pellegrini, F, Pirozzoli, Mc, Sacco, M, Valentini, M, Mcardle, Cs, Smith, Dc, Stallard, S, Dent, Dm, Gudgeon, Ca, Hacking, A, Murray, E, Panieri, E, Werner, Id, Galligioni, E, Leone, B, Vallejo, Ct, Zwenger, A, Lopez, M, Erazo, A, Medina, Jy, Horiguchi, J, Takei, H, Fentiman, Is, Hayward, Jl, Rubens, Rd, Skilton, D, Scheurlen, H, Sohn, Hc, Untch, M, Dafni, U, Markopoulos, C, Fountzilas, G, Mavroudis, D, Klefstrom, P, Blomqvist, C, Saarto, T, Gallen, M, Tinterri, C, Margreiter, R, De Lafontan, B, Mihura, J, Roché, H, Asselain, B, Salmon, Rj, Vilcoq, Jr, André, F, Delaloge, S, Koscielny, S, Michiels, S, Rubino, C, A'Hern, R, Ellis, P, Kilburn, L, Yarnold, Jr, Benraadt, J, Kooi, M, Van De Velde Ao, Van Dongen Ja, Vermorken, Jb, Castiglione, M, Colleoni, M, Collins, J, Gelber, Rd, Lindtner, J, Price, Kn, Regan, Mm, Rudenstam, Cm, Senn, Hj, Thuerlimann, B, Bliss, Jm, Chilvers, Ced, Coombes, Rc, Hall, E, Marty, M, Buyse, M, Possinger, K, Schmid, P, Wallwiener, D, Bighin, C, Bruzzi, P, Del Mastro, L, Dozin, B, Pastorino, S, Pronzato, P, Sertoli, Mr, Foster, L, George, Wd, Stewart, Hj, Stroner, P, Borovik, R, Hayat, H, Inbar, Mj, Peretz, T, Robinson, E, Camerini, T, Formelli, F, Martelli, G, Di Mauro Mg, Perrone, F, Amadori, D, Martoni, A, Pannuti, F, Camisa, R, Musolino, A, Passalacqua, R, Iwata, H, Shien, T, Ikeda, T, Inokuchi, K, Sawa, K, Sonoo, H, Sadoon, M, Tulusan, Ah, Kohno, N, Miyashita, M, Takao, S, Ahn, Jh, Jung, Kh, Korzeniowski, S, Skolyszewski, J, Ogawa, M, Yamashita, J, Bastiaannet, E, Liefers, Gj, Christiaens, R, Neven, P, Paridaens, R, Van Den Bogaert, W, Braun, S, Martin, P, Romain, S, Janauer, M, Seifert, M, Sevelda, P, Zielinski, Cc, Hakes, T, Hudis, Ca, Wittes, R, Giokas, G, Kondylis, D, Lissaios, B, De La Huerta, R, Sainz, Mg, Ro, J, Camphausen, K, Danforth, D, Lichter, A, Lippman, M, Smart, D, Steinberg, S, D’Amico, C, Lioce, M, Paradiso, A, Ohno, S, Bass, G, Brown, A, Bryant, J, Dignam, J, Fisher, B, Geyer, C, Mamounas, Ep, Redmond, C, Wickerham, L, Aihara, T, Hozumi, Y, Baum, M, Jackson, Im, Palmer, Mk, Ingle, Jn, Suman, Vj, Bengtsson, No, Emdin, S, Jonsson, H, Venturini, M, Lythgoe, Jp, Kissin, M, Erikstein, B, Hannisdal, E, Jacobsen, Ab, Reinertsen, Kv, Varhaug, Je, Gundersen, S, Hauer‐jensen, M, Høst, H, Nissen‐meyer, R, Mitchell, Ak, Robertson, Jfr, Ueo, H, Di Palma, M, Mathé, G, Misset, Jl, Levine, M, Morimoto, K, Takatsuka, Y, Crossley, E, Harris, A, Talbot, D, Taylor, M, Cocconi, G, Di Blasio, B, Ivanov, V, Paltuev, R, Semiglazov, V, Brockschmidt, J, Cooper, Mr, Falkson, Ci, Hadji, P, A’Hern, R, Makris, A, Parton, M, Pennert, K, Powles, Tj, Smith, Ie, Gazet, Jc, Browne, L, Graham, P, Corcoran, N, Clack, G, Van Poznak, C, Deshpande, N, Di Martino, L, Douglas, P, Lindtner, A, Notter, G, Bryant, Ajs, Ewing, Gh, Firth, La, Krushen‐kosloski, Jl, Anderson, H, Killander, F, Malmström, P, Rydén, L, Arnesson, Lg, Carstensen, J, Dufmats, M, Fohlin, H, Nordenskjöld, B, Söderberg, M, Carpenter, Jt, Murray, N, Royle, Gt, Simmonds, Pd, Crowley, J, Gralow, J, Hortobagyi, G, Livingston, R, Martino, S, Osborne, Ck, Ravdin, Pm, Bondesson, T, Celebioglu, F, Dahlberg, K, Fornander, T, Fredriksson, I, Frisell, J, Göransson, E, Iiristo, M, Johansson, U, Lenner, E, Löfgren, L, Nikolaidis, P, Perbeck, L, Rotstein, S, Sandelin, K, Skoog, L, Svane, G, Af Trampe, E, Wadström, C, Maibach, R, Thürlimann, B, Holli, K, Rouhento, K, Safra, T, Brenner, H, Hercbergs, A, Yoshimoto, M, Paterson, Ahg, Fyles, A, Meakin, Jw, Panzarella, T, Bahi, J, Lemonnier, J, Martin, Al, Reid, M, Spittle, M, Bishop, H, Bundred, Nj, Forsyth, S, Pinder, Se, Deutsch, Gp, Kwong, Dlw, Pai, Vr, Senanayake, F, Rubagotti, A, Hackshaw, A, Houghton, J, Ledermann, J, Monson, K, Tobias, Js, Carlomagno, C, De Laurentiis, M, De Placido, S, Williams, L, Bell, R, Hinsley, S, Marshall, Hc, Pierce, Lj, Solomayer, E, Horsman, Jm, Lester, J, Winter, Mc, Buzdar, Au, Hsu, L, Love, Rr, Ahlgren, J, Garmo, H, Holmberg, L, Liljegren, G, Lindman, H, Wärnberg, F, Asmar, L, Jones, Se, Aft, R, Gluz, O, Liedtke, C, Nitz, U, Litton, A, Wallgren, A, Karlsson, P, Linderholm, Bk, Chlebowski, Rt, Caffier, H.
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New England Journal of Medicine, 377(19), 1836-1846. MASSACHUSETTS MEDICAL SOC
New England journal of medicine, 377(19), 1836-1846. Massachussetts Medical Society
New England Journal of Medicine, 377(19), 1836-1846. MASSACHUSETTS MEDICAL SOCIETY
New England journal of medicine, 377(19), 1836-1846. Massachussetts Medical Society
New England Journal of Medicine, 377(19), 1836-1846. MASSACHUSETTS MEDICAL SOCIETY
Background The administration of endocrine therapy for 5 years substantially reduces recurrence rates during and after treatment in women with early-stage, estrogen-receptor (ER)–positive breast cancer. Extending such therapy beyond 5 years offers
Autor:
Wilcox, M. H., Gerding, D. N., Poxton, I. R., Kelly, C., Nathan, R., Birch, T., Cornely, O. A., Rahav, G., Bouza, E., Lee, C., Jenkin, G., Jensen, W., Kim, Y. -S., Yoshida, J., Gabryelski, L., Pedley, A., Eves, K., Tipping, R., Guris, D., Kartsonis, N., Playford G, Dorr M. -B., Mcgechie, D, Iredell, J, Allworth, A, Cheng, A, Choi, Nj, Thalhammer, F, Maieron, A, Wenisch, C, Meyer, B, Jacobs, F, Delmee, M, Peetermans, W, Giot, Jb, Munhoz, Al, Kallas, Eg, Ladeira, Jp, Bernstein, Cn, Grimard, D, Mcgeer, A, Poirier, A, Valiquette, L, Miller, M, Oughton, M, Trottier, S, Dolce, P, Smyth, D, Gambra, P, Palma, S, Rojas, L, Northland, R, Arellano, Mc, Perez, J, Barreto, Mf, Gomez, Jm, Ramirez, I, Correa, A, Onate, J, Rohacova, H, Stastnik, M, Zjevikova, A, Blazek, J, Kumpel, P, Petersen, Am, Gluud, Ll, Staugaard, Hm, Tvede, M, Glerup, H, Madsen, Sm, Helms, M, Naumann, R, Karthaus, M, Reinshagen, M, Raz, R, Giladi, M, Chowers, M, Bishara, J, Quirino, T, Castelli, F, Bassetti, M, Rizzardini, G, Vismara, E, Puoti, M, Viale, P, Menichetti, F, Cauda, R, Bonfanti, P, Franzetti, F, Gori, A, Minoli, L, Noriega, Er, Mills, Gd, Ritchie, S, Burns, A, Pithie, A, dos Santos RM, Aldomiro, F, Fernando, Pb, Rola, J, Reis, E, Van Zyl JH, Aboo, N, Richards, G, Hernandez, Mj, de Medrano VA, Prunonosa, Lm, Gonzalez, Jl, Reinoso, Jc, Martinez, Ar, Cisneros, Jd, Banos, Jr, Sheridan, R, Minton, J, Williams, J, Stanley, P, Guleri, A, Llewelyn, M, Todd, N, Barlow, G, Bacon, Ae, Baird, Im, Baxter, R, Zenilman, Jm, Beshay, M, Betts, Rf, Brettholz, Em, Buitrago, Mi, Carlson, Rw, Cook, Pp, Dupont, Hl, Foley, C, Freilich, B, Giron, Ja, Golan, Y, Green, S, Hall, Mc, Johnson, Dj, Jones, Rk, Graham, Dr, Kazimir, M, Keating, M, Brumble, Lm, Kumar, Pn, Liappis, Ap, Libke, R, Mehra, Pk, Overcash, Sj, Mullane, Km, Nguyen, Mh, Patel, Mc, Powers, Ck, Pullman, J, Keegan, J, Nepal, S, English, G, Ricci, Rl, Risi, Gf, Rodriguez, M, Schmitt, Cm, Sims, Md, Kamepalli, R, Tural, A, Vazquez, Ja, Alangaden, Gj, Weavind, Lm, Young, Ma, Chen, St, Liu, E, Nguyen, Hh, Alfonso, Tb, Muse, Dd, Orenstein, R, Yacyshyn, B, Gebhard, Re, Dinges, W, Bolton, M, Rubin, M, Kuemmerle, Jf, Limaye, Ap, Friedenberg, Ka, Hiemenz, Jw, Quadri, A, Martinez, Jv, Barcan, La, Cordova, E, Mykietiuk, A, Losso, M, Fedorak, Rn, Steiner, T, Gerson, M, Weiss, K, Dlouhy, P, Vitous, A, Benes, J, Husa, P, Knizek, P, Anttila, Vj, Broas, M, Camou, F, Postil, D, Launay, O, Corroyer-Simovic, B, Meynard, Jl, Schneider, S, Molina, Jm, Neau, D, Zalcman, G, Boutoille, D, Ostermann, H, Heinz, W, Reuter, S, Oren, I, Schiff, E, Umemoto, T, Masubuchi, T, Mukawa, K, Yasuda, K, Imokawa, S, Fukuda, K, Ohta, H, Harada, N, Fujii, S, Tamaki, S, Yasui, S, Furukawa, K, Takahashi, M, Uraoka, T, Watanabe, M, Ikehara, Y, Kodaira, M, Komatsu, H, Higashi, K, Taguchi, F, Ura, N, Serizawa, Y, Fukuchi, T, Ashikawa, T, Shabana, M, Okubo, M, Matsumoto, M, Kurihara, A, Miyasaka, E, Shimizu, M, Tominaga, H, Kubota, T, Kashiwazaki, M, Masuda, Y, Terasaki, S, Okafuji, H, Mieno, H, Urabe, T, Okamoto, E, Kajimura, M, Yamagishi, Y, Rydzewska, G, Mach, T, Ciechanowski, K, Podlasin, R, Tomasiewicz, K, Janczewska-Kazek, E, Czarnobilski, K, Halota, W, Gryglewska, B, Plesniak, R, Dabrowiecki, P, Lipowski, D, Simanenkov, V, Shcheglova, L, Uspenskiy, Y, Cheganov, A, Han, Ds, Kim, Js, Hong, Sp, Kim, Ti, Jang, Bi, Byeon, Js, Kim, E, Kim, Mj, Lee, J, Pai, H, Cheong, Hj, Lee, S, Loyarte, Ja, Gonzalez, Jc, Santiago, Eb, Lopez, Jr, Baranda, Jm, Viladomiu, As, Calbo, E, Lannergard, A, Falt, J, Gardlund, B, Andersson, Lm, Fraenkel, Cj, Rombo, L, Widmer, A, Chen, Yc, Sheng, Wh, Wang, Fd, Wang, Nc, Lee, Ch, Chen, Yh, Chuang, Yc, Unal, S, Ozaras, R, Esen, S, Ural, O, Ayaz, C, Sakarya, S, Celebi, A, Mistik, R, Bedimo, R, Bressler, A, Mckinley, Mj, Quirk, D, Talansky, Al, Agronin, Me, Akhrass, Fa, Ali, M, Alrabaa, Sf, Assi, Ma, Calfee, Dp, Carson, P, Mariani, Pg, Guerrero, D, Dubberke, Er, Hardi, R, Hazan-Steinberg, S, Itani, Km, Jauregui-Peredo, El, Kasabji, A, Hameed, M, Murillo, A, Odio, Aj, Shah, P, Braun, Ti, Slim, J, Sloan, L, Srinivasan, S, Tan, Mj, Clough, La, Herr, D, Miller, Lg, Dorfmeister, J, Khan, O, Melik-Abrahamian, F.
Publikováno v:
Wilcox, M H, Gerding, D N, Poxton, I R, Kelly, C, Nathan, R, Birch, T, Cornely, O A, Rahav, G, Bouza, E, Lee, C, Jenkin, G, Jensen, W, Kim, Y-S, Yoshida, J, Gabryelski, L, Pedley, A, Eves, K, Tipping, R, Guris, D, Kartsonis, N, Dorr, M-B, MODIFY I and MODIFY II Investigators & Glerup, H 2017, ' Bezlotoxumab for Prevention of Recurrent Clostridium difficile Infection ', The New England Journal of Medicine, vol. 376, no. 4, pp. 305-317 . https://doi.org/10.1056/NEJMoa1602615
BACKGROUND: Clostridium difficile is the most common cause of infectious diarrhea in hospitalized patients. Recurrences are common after antibiotic therapy. Actoxumab and bezlotoxumab are human monoclonal antibodies against C. difficile toxins A and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05bc273f9f36169cf744b9e7b515f01e
http://hdl.handle.net/11568/1022277
http://hdl.handle.net/11568/1022277
Autor:
Amare, Azmeraw T., Schubert, Klaus Oliver, Hou, Liping, Clark, Scott R., Papiol, Sergi, Cearns, Micah, Heilbronner, Urs, Degenhardt, Franziska, Tekola-Ayele, Fasil, Hsu, Yi Hsiang, Shekhtman, Tatyana, Adli, Mazda, Akula, Nirmala, Akiyama, Kazufumi, Ardau, Raffaella, Arias, Bárbara, Aubry, Jean Michel, Backlund, Lena, Bhattacharjee, Abesh Kumar, Bellivier, Frank, Benabarre, Antonio, Bengesser, Susanne, Biernacka, Joanna M., Birner, Armin, Brichant-Petitjean, Clara, Cervantes, Pablo, Chen, Hsi Chung, Chillotti, Caterina, Cichon, Sven, Cruceanu, Cristiana, Czerski, Piotr M., Dalkner, Nina, Dayer, Alexandre, Del Zompo, Maria, DePaulo, J. Raymond, Étain, Bruno, Jamain, Stephane, Falkai, Peter, Forstner, Andreas J., Frisen, Louise, Frye, Mark A., Fullerton, Janice M., Gard, Sébastien, Garnham, Julie S., Goes, Fernando S., Grigoroiu-Serbanescu, Maria, Grof, Paul, Hashimoto, Ryota, Hauser, Joanna, Herms, Stefan, Hoffmann, Per, Hofmann, Andrea, Jiménez, Esther, Kahn, Jean Pierre, Kassem, Layla, Kuo, Po Hsiu, Kato, Tadafumi, Kelsoe, John R., Kittel-Schneider, Sarah, Kliwicki, Sebastian, König, Barbara, Kusumi, Ichiro, Laje, Gonzalo, Landén, Mikael, Lavebratt, Catharina, Leboyer, Marion, Leckband, Susan G., Tortorella, Alfonso, Manchia, Mirko, Martinsson, Lina, McCarthy, Michael J., McElroy, Susan L., Colom, Francesc, Mitjans, Marina, Mondimore, Francis M., Monteleone, Palmiero, Nievergelt, Caroline M., Nöthen, Markus M., Novák, Tomas, O’Donovan, Claire, Ozaki, Norio, Ösby, Urban, Pfennig, Andrea, Potash, James B., Reif, Andreas, Wray, Naomi R., Ripke, Stephan, Mattheisen, Manuel, Trzaskowski, Maciej, Byrne, Enda M., Abdellaoui, Abdel, Adams, Mark J., Agerbo, Esben, Air, Tracy M., Andlauer, Till F.M., Bacanu, Silviu Alin, Bækvad-Hansen, Marie, Beekman, Aartjan T.F., Bigdeli, Tim B., Binder, Elisabeth B., Blackwood, Douglas H.R., Bryois, Julien, Buttenschøn, Henriette N., Bybjerg-Grauholm, Jonas, Cai, Na, Castelao, Enrique, Christensen, Jane varregaard, Clarke, Toni Kim, Coleman, Jonathan R.I., Colodro-Conde, Lucía, Couvy-Duchesne, Baptiste, Craddock, Nick, Crawford, Gregory E., Davies, Gail, Deary, Ian J., Derks, Eske M., Direk, Nese, Dolan, Conor V., Dunn, Erin C., Eley, Thalia C., Escott-Price, Valentina, Kiadeh, Farnush Farhadi Hassan, Finucane, Hilary K., Frank, Josef, Gaspar, Héléna A., Gill, Michael, Gordon, Scott D., Grove, Jakob, Hall, Lynsey S., Hansen, Christine Søholm, Hansen, Thomas F., Hickie, Ian B., Homuth, Georg, Horn, Carsten, Hottenga, Jouke Jan, Hougaard, David M., Ising, Marcus, Jansen, Rick, Jorgenson, Eric, Knowles, James A., Kohane, Isaac S., Kraft, Julia, Kretzschmar, Warren W., Krogh, Jesper, Kutalik, Zoltán, Li, Yihan, Lind, Penelope A., MacIntyre, Donald J., MacKinnon, Dean F., Maier, Robert M., Maier, Wolfgang, Marchini, Jonathan, Mbarek, Hamdi, McGrath, Patrick, McGuffin, Peter, Medland, Sarah E., Mehta, Divya, Middeldorp, Christel M., Mihailov, Evelin, Milaneschi, Yuri, Milani, Lili, Montgomery, Grant W., Mostafavi, Sara, Mullins, Niamh, Nauck, Matthias, Ng, Bernard, Nivard, Michel G., Nyholt, Dale R., O’Reilly, Paul F., Oskarsson, Hogni, Owen, Michael J., Painter, Jodie N., Pedersen, Carsten Bøcker, Pedersen, Marianne Giørtz, Peterson, Roseann E., Pettersson, Erik, Peyrot, Wouter J., Pistis, Giorgio, Posthuma, Danielle, Quiroz, Jorge A., Qvist, Per, Rice, John P., Riley, Brien P., Rivera, Margarita, Mirza, Saira Saeed, Schoevers, Robert, Schulte, Eva C., Shen, Ling, Shi, Jianxin, Shyn, Stanley I., Sigurdsson, Engilbert, Sinnamon, Grant C.B., Smit, Johannes H., Smith, Daniel J., Stefansson, Hreinn, Steinberg, Stacy, Streit, Fabian, Strohmaier, Jana, Tansey, Katherine E., Teismann, Henning, Teumer, Alexander, Thompson, Wesley, Thomson, Pippa A., Thorgeirsson, Thorgeir E., Traylor, Matthew, Treutlein, Jens, Trubetskoy, Vassily, Uitterlinden, André G., Umbricht, Daniel, Van der Auwera, Sandra, van Hemert, Albert M., Viktorin, Alexander, Visscher, Peter M., Wang, Yunpeng, Webb, Bradley T., Weinsheimer, Shantel Marie, Wellmann, Jürgen, Willemsen, Gonneke, Witt, Stephanie H., Wu, Yang, Xi, Hualin S., Yang, Jian, Zhang, Futao, Arolt, Volker, Baune, Bernhard T., Berger, Klaus, Boomsma, Dorret I., Dannlowski, Udo, de Geus, E. J.C., Domenici, Enrico, Domschke, Katharina, Esko, Tõnu, Grabe, Hans J., Hamilton, Steven P., Hayward, Caroline, Heath, Andrew C., Kendler, Kenneth S., Kloiber, Stefan, Lewis, Glyn, Li, Qingqin S., Lucae, Susanne, Madden, Pamela A.F., Magnusson, Patrik K., Martin, Nicholas G., McIntosh, Andrew M., Metspalu, Andres, Mors, Ole, Mortensen, Preben Bo, Müller-Myhsok, Bertram, Nordentoft, Merete, O’Donovan, Michael C., Paciga, Sara A., Pedersen, Nancy L., Penninx, Brenda W.J.H., Perlis, Roy H., Porteous, David J., Preisig, Martin, Rietschel, Marcella, Schaefer, Catherine, Schulze, Thomas G., Smoller, Jordan W., Stefansson, Kari, Tiemeier, Henning, Uher, Rudolf, Völzke, Henry, Weissman, Myrna M., Werge, Thomas, Lewis, Cathryn M., Levinson, Douglas F., Breen, Gerome, Børglum, Anders D., Sullivan, Patrick F., Reininghaus, Eva, Rouleau, Guy A., Rybakowski, Janusz K., Schalling, Martin, Schofield, Peter R., Schweizer, Barbara W., Severino, Giovanni, Shilling, Paul D., Shimoda, Katzutaka, Simhandl, Christian, Slaney, Claire M., Squassina, Alessio, Stamm, Thomas, Stopkova, Pavla, Maj, Mario, Turecki, Gustavo, Vieta, Eduard, Veeh, Julia, Wright, Adam, Zandi, Peter P., Mitchell, Philip B., Bauer, Michael, Alda, Martin, McMahon, Francis J.
Publikováno v:
Molecular Psychiatry, 26(6), 2457-2470. Nature Publishing Group
Amare, A T, Baune, B T, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Abdellaoui, A, Dolan, C V, Hottenga, J J, Mbarek, H, Middeldorp, C M, Nivard, M G, Willemsen, G, Boomsma, D I, de Geus, E J C, Beekman, A F T, Jansen, R, Milaneschi, Y, Peyrot, W J, Smit, J H, W J H Penninx, B & Posthuma, D 2021, ' Association of polygenic score for major depression with response to lithium in patients with bipolar disorder ', Molecular Psychiatry, vol. 26, no. 6, pp. 2457-2470 . https://doi.org/10.1038/s41380-020-0689-5
Amare, A T, Schubert, K O, Hou, L, Clark, S R, Papiol, S, Cearns, M, Heilbronner, U, Degenhardt, F, Tekola-Ayele, F, Hsu, Y H, Shekhtman, T, Adli, M, Akula, N, Akiyama, K, Ardau, R, Arias, B, Aubry, J M, Backlund, L, Bhattacharjee, A K, Bellivier, F, Benabarre, A, Bengesser, S, Biernacka, J M, Birner, A, Brichant-Petitjean, C, Cervantes, P, Chen, H C, Chillotti, C, Cichon, S, Cruceanu, C, Czerski, P M, Dalkner, N, Dayer, A, Del Zompo, M, DePaulo, J R, Étain, B, Jamain, S, Falkai, P, Forstner, A J, Frisen, L, Frye, M A, Fullerton, J M, Nordentoft, M, Werge, T, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Wray, N R, Ripke, S, Matthiesen, M, Agerbo, E, Bækvad-Hansen, M, Buttenschøn, H N, Bybjerg-Grauholm, J, Grove, J, Hansen, C S, Hansen, T F, Hougaard, D M, Krogh, J, Pedersen, C B, Pedersen, M G, Qvist, P, Thompson, W K, Wang, Y, Weinsheimer, S M, Mortensen, P B, Christensen, J V & Børglum, A D 2021, ' Association of polygenic score for major depression with response to lithium in patients with bipolar disorder ', Molecular Psychiatry, vol. 26, pp. 2457–2470 . https://doi.org/10.1038/s41380-020-0689-5
Molecular psychiatry 26(6), 2457-2470 (2021). doi:10.1038/s41380-020-0689-5
Molecular Psychiatry
Molecular Psychiatry, 2021, Online ahead of print. ⟨10.1038/s41380-020-0689-5⟩
Amare, A T, Schubert, K O, Hou, L, Clark, S R, Papiol, S, Cearns, M, Heilbronner, U, Degenhardt, F, Tekola-Ayele, F, Hsu, Y H, Shekhtman, T, Adli, M, Akula, N, Akiyama, K, Ardau, R, Arias, B, Aubry, J M, Backlund, L, Bhattacharjee, A K, Bellivier, F, Benabarre, A, Bengesser, S, Biernacka, J M, Birner, A, Brichant-Petitjean, C, Cervantes, P, Chen, H C, Chillotti, C, Cichon, S, Cruceanu, C, Czerski, P M, Dalkner, N, Dayer, A, Del Zompo, M, DePaulo, J R, Étain, B, Jamain, S, Falkai, P, Forstner, A J, Frisen, L, Frye, M A, Fullerton, J M, Gard, S, Garnham, J S, Goes, F S, Grigoroiu-Serbanescu, M, Grof, P, Hashimoto, R, Hauser, J, Herms, S, Hoffmann, P, Hofmann, A, Jiménez, E, Kahn, J P, Kassem, L, Kuo, P H, Kato, T, Kelsoe, J R, Kittel-Schneider, S, Kliwicki, S, König, B, Kusumi, I, Laje, G, Landén, M, Lavebratt, C, Leboyer, M, Leckband, S G, Tortorella, A, Manchia, M, Martinsson, L, McCarthy, M J, McElroy, S L, Colom, F, Mitjans, M, Mondimore, F M, Monteleone, P, Nievergelt, C M, Nöthen, M M, Novák, T, O’Donovan, C, Ozaki, N, Ösby, U, Pfennig, A, Potash, J B, Reif, A, Wray, N R, Ripke, S, Mattheisen, M, Trzaskowski, M, Byrne, E M, Abdellaoui, A, Adams, M J, Agerbo, E, Air, T M, Andlauer, T F M, Bacanu, S A, Bækvad-Hansen, M, Beekman, A T F, Bigdeli, T B, Binder, E B, Blackwood, D H R, Bryois, J, Buttenschøn, H N, Bybjerg-Grauholm, J, Cai, N, Castelao, E, Christensen, J V, Clarke, T K, Coleman, J R I, Colodro-Conde, L, Couvy-Duchesne, B, Craddock, N, Crawford, G E, Davies, G, Deary, I J, Degenhardt, F, Derks, E M, Direk, N, Dolan, C V, Dunn, E C, Eley, T C, Escott-Price, V, Kiadeh, F F H, Finucane, H K, Forstner, A J, Frank, J, Gaspar, H A, Gill, M, Goes, F S, Gordon, S D, Grove, J, Hall, L S, Hansen, C S, Hansen, T F, Herms, S, Hickie, I B, Hoffmann, P, Homuth, G, Horn, C, Hottenga, J J, Hougaard, D M, Ising, M, Jansen, R, Jorgenson, E, Knowles, J A, Kohane, I S, Kraft, J, Kretzschmar, W W, Krogh, J, Kutalik, Z, Li, Y, Lind, P A, MacIntyre, D J, MacKinnon, D F, Maier, R M, Maier, W, Marchini, J, Mbarek, H, McGrath, P, McGuffin, P, Medland, S E, Mehta, D, Middeldorp, C M, Mihailov, E, Milaneschi, Y, Milani, L, Mondimore, F M, Montgomery, G W, Mostafavi, S, Mullins, N, Nauck, M, Ng, B, Nivard, M G, Nyholt, D R, O’Reilly, P F, Oskarsson, H, Owen, M J, Painter, J N, Pedersen, C B, Pedersen, M G, Peterson, R E, Pettersson, E, Peyrot, W J, Pistis, G, Posthuma, D, Quiroz, J A, Qvist, P, Rice, J P, Riley, B P, Rivera, M, Mirza, S S, Schoevers, R, Schulte, E C, Shen, L, Shi, J, Shyn, S I, Sigurdsson, E, Sinnamon, G C B, Smit, J H, Smith, D J, Stefansson, H, Steinberg, S, Streit, F, Strohmaier, J, Tansey, K E, Teismann, H, Teumer, A, Thompson, W, Thomson, P A, Thorgeirsson, T E, Traylor, M, Treutlein, J, Trubetskoy, V, Uitterlinden, A G, Umbricht, D, Van der Auwera, S, van Hemert, A M, Viktorin, A, Visscher, P M, Wang, Y, Webb, B T, Weinsheimer, S M, Wellmann, J, Willemsen, G, Witt, S H, Wu, Y, Xi, H S, Yang, J, Zhang, F, Arolt, V, Baune, B T, Berger, K, Boomsma, D I, Cichon, S, Dannlowski, U, de Geus, E J C, DePaulo, J R, Domenici, E, Domschke, K, Esko, T, Grabe, H J, Hamilton, S P, Hayward, C, Heath, A C, Kendler, K S, Kloiber, S, Lewis, G, Li, Q S, Lucae, S, Madden, P A F, Magnusson, P K, Martin, N G, McIntosh, A M, Metspalu, A, Mors, O, Mortensen, P B, Müller-Myhsok, B, Nordentoft, M, Nöthen, M M, O’Donovan, M C, Paciga, S A, Pedersen, N L, Penninx, B W J H, Perlis, R H, Porteous, D J, Potash, J B, Preisig, M, Rietschel, M, Schaefer, C, Schulze, T G, Smoller, J W, Stefansson, K, Tiemeier, H, Uher, R, Völzke, H, Weissman, M M, Werge, T, Lewis, C M, Levinson, D F, Breen, G, Børglum, A D, Sullivan, P F, Reininghaus, E, Rouleau, G A, Rybakowski, J K, Schalling, M, Schofield, P R, Schweizer, B W, Severino, G, Shilling, P D, Shimoda, K, Simhandl, C, Slaney, C M, Squassina, A, Stamm, T, Stopkova, P, Maj, M, Turecki, G, Vieta, E, Veeh, J, Witt, S H, Wright, A, Zandi, P P, Mitchell, P B, Bauer, M, Alda, M, Rietschel, M, McMahon, F J, Schulze, T G, Baune, B T & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium 2021, ' Association of polygenic score for major depression with response to lithium in patients with bipolar disorder ', Molecular Psychiatry, vol. 26, no. 6, pp. 2457-2470 . https://doi.org/10.1038/s41380-020-0689-5
Amare, A T, Schubert, K O, Hou, L, Clark, S R, Papiol, S, Cearns, M, Heilbronner, U, Degenhardt, F, Tekola-Ayele, F, Hsu, Y-H, Shekhtman, T, Adli, M, Akula, N, Akiyama, K, Ardau, R, Arias, B, Aubry, J-M, Backlund, L, Bhattacharjee, A K, Bellivier, F, Benabarre, A, Bengesser, S, Biernacka, J M, Birner, A, Brichant-Petitjean, C, Cervantes, P, Chen, H-C, Chillotti, C, Cichon, S, Cruceanu, C, Czerski, P M, Dalkner, N, Dayer, A, Del Zompo, M, DePaulo, J R, Étain, B, Jamain, S, Falkai, P, Forstner, A J, Frisen, L, Frye, M A, Fullerton, J M, Gard, S, Garnham, J S, Goes, F S, Grigoroiu-Serbanescu, M, Grof, P, Hashimoto, R, Hauser, J, Herms, S & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium 2021, ' Association of polygenic score for major depression with response to lithium in patients with bipolar disorder ', Molecular Psychiatry, vol. 26, no. 6, pp. 2457-2470 . https://doi.org/10.1038/s41380-020-0689-5
Molecular Psychiatry, Nature Publishing Group, 2021, Online ahead of print. ⟨10.1038/s41380-020-0689-5⟩
Molecular Psychiatry (2020)
Molecular psychiatry, 26(6), 2457-2470. Nature Publishing Group
Amare, A T, Baune, B T, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Abdellaoui, A, Dolan, C V, Hottenga, J J, Mbarek, H, Middeldorp, C M, Nivard, M G, Willemsen, G, Boomsma, D I, de Geus, E J C, Beekman, A F T, Jansen, R, Milaneschi, Y, Peyrot, W J, Smit, J H, W J H Penninx, B & Posthuma, D 2021, ' Association of polygenic score for major depression with response to lithium in patients with bipolar disorder ', Molecular Psychiatry, vol. 26, no. 6, pp. 2457-2470 . https://doi.org/10.1038/s41380-020-0689-5
Amare, A T, Schubert, K O, Hou, L, Clark, S R, Papiol, S, Cearns, M, Heilbronner, U, Degenhardt, F, Tekola-Ayele, F, Hsu, Y H, Shekhtman, T, Adli, M, Akula, N, Akiyama, K, Ardau, R, Arias, B, Aubry, J M, Backlund, L, Bhattacharjee, A K, Bellivier, F, Benabarre, A, Bengesser, S, Biernacka, J M, Birner, A, Brichant-Petitjean, C, Cervantes, P, Chen, H C, Chillotti, C, Cichon, S, Cruceanu, C, Czerski, P M, Dalkner, N, Dayer, A, Del Zompo, M, DePaulo, J R, Étain, B, Jamain, S, Falkai, P, Forstner, A J, Frisen, L, Frye, M A, Fullerton, J M, Nordentoft, M, Werge, T, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Wray, N R, Ripke, S, Matthiesen, M, Agerbo, E, Bækvad-Hansen, M, Buttenschøn, H N, Bybjerg-Grauholm, J, Grove, J, Hansen, C S, Hansen, T F, Hougaard, D M, Krogh, J, Pedersen, C B, Pedersen, M G, Qvist, P, Thompson, W K, Wang, Y, Weinsheimer, S M, Mortensen, P B, Christensen, J V & Børglum, A D 2021, ' Association of polygenic score for major depression with response to lithium in patients with bipolar disorder ', Molecular Psychiatry, vol. 26, pp. 2457–2470 . https://doi.org/10.1038/s41380-020-0689-5
Molecular psychiatry 26(6), 2457-2470 (2021). doi:10.1038/s41380-020-0689-5
Molecular Psychiatry
Molecular Psychiatry, 2021, Online ahead of print. ⟨10.1038/s41380-020-0689-5⟩
Amare, A T, Schubert, K O, Hou, L, Clark, S R, Papiol, S, Cearns, M, Heilbronner, U, Degenhardt, F, Tekola-Ayele, F, Hsu, Y H, Shekhtman, T, Adli, M, Akula, N, Akiyama, K, Ardau, R, Arias, B, Aubry, J M, Backlund, L, Bhattacharjee, A K, Bellivier, F, Benabarre, A, Bengesser, S, Biernacka, J M, Birner, A, Brichant-Petitjean, C, Cervantes, P, Chen, H C, Chillotti, C, Cichon, S, Cruceanu, C, Czerski, P M, Dalkner, N, Dayer, A, Del Zompo, M, DePaulo, J R, Étain, B, Jamain, S, Falkai, P, Forstner, A J, Frisen, L, Frye, M A, Fullerton, J M, Gard, S, Garnham, J S, Goes, F S, Grigoroiu-Serbanescu, M, Grof, P, Hashimoto, R, Hauser, J, Herms, S, Hoffmann, P, Hofmann, A, Jiménez, E, Kahn, J P, Kassem, L, Kuo, P H, Kato, T, Kelsoe, J R, Kittel-Schneider, S, Kliwicki, S, König, B, Kusumi, I, Laje, G, Landén, M, Lavebratt, C, Leboyer, M, Leckband, S G, Tortorella, A, Manchia, M, Martinsson, L, McCarthy, M J, McElroy, S L, Colom, F, Mitjans, M, Mondimore, F M, Monteleone, P, Nievergelt, C M, Nöthen, M M, Novák, T, O’Donovan, C, Ozaki, N, Ösby, U, Pfennig, A, Potash, J B, Reif, A, Wray, N R, Ripke, S, Mattheisen, M, Trzaskowski, M, Byrne, E M, Abdellaoui, A, Adams, M J, Agerbo, E, Air, T M, Andlauer, T F M, Bacanu, S A, Bækvad-Hansen, M, Beekman, A T F, Bigdeli, T B, Binder, E B, Blackwood, D H R, Bryois, J, Buttenschøn, H N, Bybjerg-Grauholm, J, Cai, N, Castelao, E, Christensen, J V, Clarke, T K, Coleman, J R I, Colodro-Conde, L, Couvy-Duchesne, B, Craddock, N, Crawford, G E, Davies, G, Deary, I J, Degenhardt, F, Derks, E M, Direk, N, Dolan, C V, Dunn, E C, Eley, T C, Escott-Price, V, Kiadeh, F F H, Finucane, H K, Forstner, A J, Frank, J, Gaspar, H A, Gill, M, Goes, F S, Gordon, S D, Grove, J, Hall, L S, Hansen, C S, Hansen, T F, Herms, S, Hickie, I B, Hoffmann, P, Homuth, G, Horn, C, Hottenga, J J, Hougaard, D M, Ising, M, Jansen, R, Jorgenson, E, Knowles, J A, Kohane, I S, Kraft, J, Kretzschmar, W W, Krogh, J, Kutalik, Z, Li, Y, Lind, P A, MacIntyre, D J, MacKinnon, D F, Maier, R M, Maier, W, Marchini, J, Mbarek, H, McGrath, P, McGuffin, P, Medland, S E, Mehta, D, Middeldorp, C M, Mihailov, E, Milaneschi, Y, Milani, L, Mondimore, F M, Montgomery, G W, Mostafavi, S, Mullins, N, Nauck, M, Ng, B, Nivard, M G, Nyholt, D R, O’Reilly, P F, Oskarsson, H, Owen, M J, Painter, J N, Pedersen, C B, Pedersen, M G, Peterson, R E, Pettersson, E, Peyrot, W J, Pistis, G, Posthuma, D, Quiroz, J A, Qvist, P, Rice, J P, Riley, B P, Rivera, M, Mirza, S S, Schoevers, R, Schulte, E C, Shen, L, Shi, J, Shyn, S I, Sigurdsson, E, Sinnamon, G C B, Smit, J H, Smith, D J, Stefansson, H, Steinberg, S, Streit, F, Strohmaier, J, Tansey, K E, Teismann, H, Teumer, A, Thompson, W, Thomson, P A, Thorgeirsson, T E, Traylor, M, Treutlein, J, Trubetskoy, V, Uitterlinden, A G, Umbricht, D, Van der Auwera, S, van Hemert, A M, Viktorin, A, Visscher, P M, Wang, Y, Webb, B T, Weinsheimer, S M, Wellmann, J, Willemsen, G, Witt, S H, Wu, Y, Xi, H S, Yang, J, Zhang, F, Arolt, V, Baune, B T, Berger, K, Boomsma, D I, Cichon, S, Dannlowski, U, de Geus, E J C, DePaulo, J R, Domenici, E, Domschke, K, Esko, T, Grabe, H J, Hamilton, S P, Hayward, C, Heath, A C, Kendler, K S, Kloiber, S, Lewis, G, Li, Q S, Lucae, S, Madden, P A F, Magnusson, P K, Martin, N G, McIntosh, A M, Metspalu, A, Mors, O, Mortensen, P B, Müller-Myhsok, B, Nordentoft, M, Nöthen, M M, O’Donovan, M C, Paciga, S A, Pedersen, N L, Penninx, B W J H, Perlis, R H, Porteous, D J, Potash, J B, Preisig, M, Rietschel, M, Schaefer, C, Schulze, T G, Smoller, J W, Stefansson, K, Tiemeier, H, Uher, R, Völzke, H, Weissman, M M, Werge, T, Lewis, C M, Levinson, D F, Breen, G, Børglum, A D, Sullivan, P F, Reininghaus, E, Rouleau, G A, Rybakowski, J K, Schalling, M, Schofield, P R, Schweizer, B W, Severino, G, Shilling, P D, Shimoda, K, Simhandl, C, Slaney, C M, Squassina, A, Stamm, T, Stopkova, P, Maj, M, Turecki, G, Vieta, E, Veeh, J, Witt, S H, Wright, A, Zandi, P P, Mitchell, P B, Bauer, M, Alda, M, Rietschel, M, McMahon, F J, Schulze, T G, Baune, B T & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium 2021, ' Association of polygenic score for major depression with response to lithium in patients with bipolar disorder ', Molecular Psychiatry, vol. 26, no. 6, pp. 2457-2470 . https://doi.org/10.1038/s41380-020-0689-5
Amare, A T, Schubert, K O, Hou, L, Clark, S R, Papiol, S, Cearns, M, Heilbronner, U, Degenhardt, F, Tekola-Ayele, F, Hsu, Y-H, Shekhtman, T, Adli, M, Akula, N, Akiyama, K, Ardau, R, Arias, B, Aubry, J-M, Backlund, L, Bhattacharjee, A K, Bellivier, F, Benabarre, A, Bengesser, S, Biernacka, J M, Birner, A, Brichant-Petitjean, C, Cervantes, P, Chen, H-C, Chillotti, C, Cichon, S, Cruceanu, C, Czerski, P M, Dalkner, N, Dayer, A, Del Zompo, M, DePaulo, J R, Étain, B, Jamain, S, Falkai, P, Forstner, A J, Frisen, L, Frye, M A, Fullerton, J M, Gard, S, Garnham, J S, Goes, F S, Grigoroiu-Serbanescu, M, Grof, P, Hashimoto, R, Hauser, J, Herms, S & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium 2021, ' Association of polygenic score for major depression with response to lithium in patients with bipolar disorder ', Molecular Psychiatry, vol. 26, no. 6, pp. 2457-2470 . https://doi.org/10.1038/s41380-020-0689-5
Molecular Psychiatry, Nature Publishing Group, 2021, Online ahead of print. ⟨10.1038/s41380-020-0689-5⟩
Molecular Psychiatry (2020)
Molecular psychiatry, 26(6), 2457-2470. Nature Publishing Group
© 2020, The Author(s), under exclusive licence to Springer Nature Limited.Lithium is a first-line medication for bipolar disorder (BD), but only one in three patients respond optimally to the drug. Since evidence shows a strong clinical and genetic
Autor:
Jonathan R.I. Coleman, Héléna A. Gaspar, Julien Bryois, Gerome Breen, Enda M. Byrne, Andreas J. Forstner, Peter A. Holmans, Christiaan A. de Leeuw, Manuel Mattheisen, Andrew McQuillin, Jennifer M. Whitehead Pavlides, Tune H. Pers, Stephan Ripke, Eli A. Stahl, Stacy Steinberg, Vassily Trubetskoy, Maciej Trzaskowski, Yunpeng Wang, Liam Abbott, Abdel Abdellaoui, Mark J. Adams, Annelie Nordin Adolfsson, Esben Agerbo, Huda Akil, Diego Albani, Ney Alliey-Rodriguez, Thomas D. Als, Till F.M. Andlauer, Adebayo Anjorin, Verneri Antilla, Sandra Van der Auwera, Swapnil Awasthi, Silviu-Alin Bacanu, Judith A. Badner, Marie Bækvad-Hansen, Jack D. Barchas, Nicholas Bass, Michael Bauer, Aartjan T.F. Beekman, Richard Belliveau, Sarah E. Bergen, Tim B. Bigdeli, Elisabeth B. Binder, Erlend Bøen, Marco Boks, James Boocock, Monika Budde, William Bunney, Margit Burmeister, Henriette N. Buttenschøn, Jonas Bybjerg-Grauholm, William Byerley, Na Cai, Miquel Casas, Enrique Castelao, Felecia Cerrato, Pablo Cervantes, Kimberly Chambert, Alexander W. Charney, Danfeng Chen, Jane Hvarregaard Christensen, Claire Churchhouse, David St Clair, Toni-Kim Clarke, Lucía Colodro-Conde, William Coryell, Baptiste Couvy-Duchesne, David W. Craig, Gregory E. Crawford, Cristiana Cruceanu, Piotr M. Czerski, Anders M. Dale, Gail Davies, Ian J. Deary, Franziska Degenhardt, Jurgen Del-Favero, J Raymond DePaulo, Eske M. Derks, Nese Direk, Srdjan Djurovic, Amanda L. Dobbyn, Conor V. Dolan, Ashley Dumont, Erin C. Dunn, Thalia C. Eley, Torbjørn Elvsåshagen, Valentina Escott-Price, Chun Chieh Fan, Hilary K. Finucane, Sascha B. Fischer, Matthew Flickinger, Jerome C. Foo, Tatiana M. Foroud, Liz Forty, Josef Frank, Christine Fraser, Nelson B. Freimer, Louise Frisén, Katrin Gade, Diane Gage, Julie Garnham, Claudia Giambartolomei, Fernando S. Goes, Jaqueline Goldstein, Scott D. Gordon, Katherine Gordon-Smith, Elaine K. Green, Melissa J. Green, Tiffany A. Greenwood, Jakob Grove, Weihua Guan, Lynsey S. Hall, Marian L. Hamshere, Christine Søholm Hansen, Thomas F. Hansen, Martin Hautzinger, Urs Heilbronner, Albert M. van Hemert, Stefan Herms, Ian B. Hickie, Maria Hipolito, Per Hoffmann, Dominic Holland, Georg Homuth, Carsten Horn, Jouke-Jan Hottenga, Laura Huckins, Marcus Ising, Stéphane Jamain, Rick Jansen, Jessica S. Johnson, Simone de Jong, Eric Jorgenson, Anders Juréus, Radhika Kandaswamy, Robert Karlsson, James L. Kennedy, Farnush Farhadi Hassan Kiadeh, Sarah Kittel-Schneider, James A. Knowles, Manolis Kogevinas, Isaac S. Kohane, Anna C. Koller, Julia Kraft, Warren W. Kretzschmar, Jesper Krogh, Ralph Kupka, Zoltán Kutalik, Catharina Lavebratt, Jacob Lawrence, William B. Lawson, Markus Leber, Phil H. Lee, Shawn E. Levy, Jun Z. Li, Yihan Li, Penelope A. Lind, Chunyu Liu, Loes M. Olde Loohuis, Anna Maaser, Donald J. MacIntyre, Dean F. MacKinnon, Pamela B. Mahon, Wolfgang Maier, Robert M. Maier, Jonathan Marchini, Lina Martinsson, Hamdi Mbarek, Steve McCarroll, Patrick McGrath, Peter McGuffin, Melvin G. McInnis, James D. McKay, Helena Medeiros, Sarah E. Medland, Divya Mehta, Fan Meng, Christel M. Middeldorp, Evelin Mihailov, Yuri Milaneschi, Lili Milani, Saira Saeed Mirza, Francis M. Mondimore, Grant W. Montgomery, Derek W. Morris, Sara Mostafavi, Thomas W. Mühleisen, Niamh Mullins, Matthias Nauck, Bernard Ng, Hoang Nguyen, Caroline M. Nievergelt, Michel G. Nivard, Evaristus A. Nwulia, Dale R. Nyholt, Claire O'Donovan, Paul F. O'Reilly, Anil P.S. Ori, Lilijana Oruc, Urban Ösby, Hogni Oskarsson, Jodie N. Painter, José Guzman Parra, Carsten Bøcker Pedersen, Marianne Giørtz Pedersen, Amy Perry, Roseann E. Peterson, Erik Pettersson, Wouter J. Peyrot, Andrea Pfennig, Giorgio Pistis, Shaun M. Purcell, Jorge A. Quiroz, Per Qvist, Eline J. Regeer, Andreas Reif, Céline S. Reinbold, John P. Rice, Brien P. Riley, Fabio Rivas, Margarita Rivera, Panos Roussos, Douglas M. Ruderfer, Euijung Ryu, Cristina Sánchez-Mora, Alan F. Schatzberg, William A. Scheftner, Robert Schoevers, Nicholas J. Schork, Eva C. Schulte, Tatyana Shehktman, Ling Shen, Jianxin Shi, Paul D. Shilling, Stanley I. Shyn, Engilbert Sigurdsson, Claire Slaney, Olav B. Smeland, Johannes H. Smit, Daniel J. Smith, Janet L. Sobell, Anne T. Spijker, Michael Steffens, John S. Strauss, Fabian Streit, Jana Strohmaier, Szabolcs Szelinger, Katherine E. Tansey, Henning Teismann, Alexander Teumer, Robert C. Thompson, Wesley Thompson, Pippa A. Thomson, Thorgeir E. Thorgeirsson, Matthew Traylor, Jens Treutlein, André G. Uitterlinden, Daniel Umbricht, Helmut Vedder, Alexander Viktorin, Peter M. Visscher, Weiqing Wang, Stanley J. Watson, Bradley T. Webb, Cynthia Shannon Weickert, Thomas W. Weickert, Shantel Marie Weinsheimer, Jürgen Wellmann, Gonneke Willemsen, Stephanie H. Witt, Yang Wu, Hualin S. Xi, Wei Xu, Jian Yang, Allan H. Young, Peter Zandi, Peng Zhang, Futao Zhang, Sebastian Zollner, Rolf Adolfsson, Ingrid Agartz, Martin Alda, Volker Arolt, Lena Backlund, Bernhard T. Baune, Frank Bellivier, Klaus Berger, Wade H. Berrettini, Joanna M. Biernacka, Douglas H.R. Blackwood, Michael Boehnke, Dorret I. Boomsma, Aiden Corvin, Nicholas Craddock, Mark J. Daly, Udo Dannlowski, Enrico Domenici, Katharina Domschke, Tõnu Esko, Bruno Etain, Mark Frye, Janice M. Fullerton, Elliot S. Gershon, E.J.C. de Geus, Michael Gill, Fernando Goes, Hans J. Grabe, Maria Grigoroiu-Serbanescu, Steven P. Hamilton, Joanna Hauser, Caroline Hayward, Andrew C. Heath, David M. Hougaard, Christina M. Hultman, Ian Jones, Lisa A. Jones, René S. Kahn, Kenneth S. Kendler, George Kirov, Stefan Kloiber, Mikael Landén, Marion Leboyer, Glyn Lewis, Qingqin S. Li, Jolanta Lissowska, Susanne Lucae, Pamela A.F. Madden, Patrik K. Magnusson, Nicholas G. Martin, Fermin Mayoral, Susan L. McElroy, Andrew M. McIntosh, Francis J. McMahon, Ingrid Melle, Andres Metspalu, Philip B. Mitchell, Gunnar Morken, Ole Mors, Preben Bo Mortensen, Bertram Müller-Myhsok, Richard M. Myers, Benjamin M. Neale, Vishwajit Nimgaonkar, Merete Nordentoft, Markus M. Nöthen, Michael C. O'Donovan, Ketil J. Oedegaard, Michael J. Owen, Sara A. Paciga, Carlos Pato, Michele T. Pato, Nancy L. Pedersen, Brenda W.J. H. Penninx, Roy H. Perlis, David J. Porteous, Danielle Posthuma, James B. Potash, Martin Preisig, Josep Antoni Ramos-Quiroga, Marta Ribasés, Marcella Rietschel, Guy A. Rouleau, Catherine Schaefer, Martin Schalling, Peter R. Schofield, Thomas G. Schulze, Alessandro Serretti, Jordan W. Smoller, Hreinn Stefansson, Kari Stefansson, Eystein Stordal, Henning Tiemeier, Gustavo Turecki, Rudolf Uher, Arne E. Vaaler, Eduard Vieta, John B. Vincent, Henry Völzke, Myrna M. Weissman, Thomas Werge, Ole A. Andreassen, Anders D. Børglum, Sven Cichon, Howard J. Edenberg, Arianna Di Florio, John Kelsoe, Douglas F. Levinson, Cathryn M. Lewis, John I. Nurnberger, Roel A. Ophoff, Laura J. Scott, Pamela Sklar, Patrick F. Sullivan, Naomi R. Wray
Publikováno v:
Biological Psychiatry, 88(2), 169-184. Elsevier USA
Coleman, J R I, Breen, G, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Abdellaoui, A, Derks, E M, Dolan, C V, Hottenga, J J, Jansen, R, Mbarek, H, Middeldorp, C M, Milaneschi, Y, Nivard, M G, Peyrot, W J, Willemsen, G, Boomsma, D I, de Geus, E J C, W J H Penninx, B & Posthuma, D 2020, ' The Genetics of the Mood Disorder Spectrum : Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls ', Biological Psychiatry, vol. 88, no. 2, pp. 169-184 . https://doi.org/10.1016/j.biopsych.2019.10.015
Biological psychiatry
Biol Psychiatry
Coleman, J R I, Gaspar, H A, Bryois, J, Breen, G, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium & Christensen, J H 2020, ' The Genetics of the Mood Disorder Spectrum : Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls ', Biological Psychiatry, vol. 88, no. 2, pp. 169-184 . https://doi.org/10.1016/j.biopsych.2019.10.015
Psychiatric Genomics Consortium 2019, ' The genetics of the mood disorder spectrum: genome-wide association analyses of over 185,000 cases and 439,000 controls ', Biological Psychiatry . https://doi.org/10.1016/j.biopsych.2019.10.015
Biological psychiatry 88(2), P169-184, (2020). doi:10.1016/j.biopsych.2019.10.015
Biological Psychiatry, 88(2), 169-184. Elsevier Inc.
Biological psychiatry, 88(2), 169-184. Elsevier USA
Coleman, J R I, Gaspar, H A, Bryois, J & Breen, G 2020, ' The genetics of the mood disorder spectrum: genome-wide association analyses of over 185,000 cases and 439,000 controls ', Biological psychiatry .
Coleman, J R I, Gaspar, H A, Bryois, J, Byrne, E M, Forstner, A J, Holmans, P A, de Leeuw, C A, Mattheisen, M, McQuillin, A, Whitehead Pavlides, J M, Pers, T H, Ripke, S, Stahl, E A, Steinberg, S, Trubetskoy, V, Trzaskowski, M, Wang, Y, Abbott, L, Abdellaoui, A, Adams, M J, Adolfsson, A N, Agerbo, E, Akil, H, Albani, D, Alliey-Rodriguez, N, Als, T D, Andlauer, T F M, Anjorin, A, Antilla, V, Van der Auwera, S, Awasthi, S, Bacanu, S A, Badner, J A, Bækvad-Hansen, M, Barchas, J D, Bass, N, Bauer, M, Beekman, A T F, Belliveau, R, Bergen, S E, Bigdeli, T B, Binder, E B, Bøen, E, Hansen, C S, Hansen, T F, Krogh, J, Pedersen, C B, Pedersen, M G, Nordentoft, M, Werge, T, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium 2020, ' The Genetics of the Mood Disorder Spectrum : Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls ', Biological Psychiatry, vol. 88, no. 2, pp. 169-184 . https://doi.org/10.1016/j.biopsych.2019.10.015
Print: 0006-3223
2020, ' The Genetics of the Mood Disorder Spectrum : Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls ', Biological psychiatry, vol. 88, no. 2, pp. 169-184 . https://doi.org/10.1016/j.biopsych.2019.10.015
Biological Psychiatry
Coleman, J R I, Breen, G, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Abdellaoui, A, Derks, E M, Dolan, C V, Hottenga, J J, Jansen, R, Mbarek, H, Middeldorp, C M, Milaneschi, Y, Nivard, M G, Peyrot, W J, Willemsen, G, Boomsma, D I, de Geus, E J C, W J H Penninx, B & Posthuma, D 2020, ' The Genetics of the Mood Disorder Spectrum : Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls ', Biological Psychiatry, vol. 88, no. 2, pp. 169-184 . https://doi.org/10.1016/j.biopsych.2019.10.015
Biological psychiatry
Biol Psychiatry
Coleman, J R I, Gaspar, H A, Bryois, J, Breen, G, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium & Christensen, J H 2020, ' The Genetics of the Mood Disorder Spectrum : Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls ', Biological Psychiatry, vol. 88, no. 2, pp. 169-184 . https://doi.org/10.1016/j.biopsych.2019.10.015
Psychiatric Genomics Consortium 2019, ' The genetics of the mood disorder spectrum: genome-wide association analyses of over 185,000 cases and 439,000 controls ', Biological Psychiatry . https://doi.org/10.1016/j.biopsych.2019.10.015
Biological psychiatry 88(2), P169-184, (2020). doi:10.1016/j.biopsych.2019.10.015
Biological Psychiatry, 88(2), 169-184. Elsevier Inc.
Biological psychiatry, 88(2), 169-184. Elsevier USA
Coleman, J R I, Gaspar, H A, Bryois, J & Breen, G 2020, ' The genetics of the mood disorder spectrum: genome-wide association analyses of over 185,000 cases and 439,000 controls ', Biological psychiatry .
Coleman, J R I, Gaspar, H A, Bryois, J, Byrne, E M, Forstner, A J, Holmans, P A, de Leeuw, C A, Mattheisen, M, McQuillin, A, Whitehead Pavlides, J M, Pers, T H, Ripke, S, Stahl, E A, Steinberg, S, Trubetskoy, V, Trzaskowski, M, Wang, Y, Abbott, L, Abdellaoui, A, Adams, M J, Adolfsson, A N, Agerbo, E, Akil, H, Albani, D, Alliey-Rodriguez, N, Als, T D, Andlauer, T F M, Anjorin, A, Antilla, V, Van der Auwera, S, Awasthi, S, Bacanu, S A, Badner, J A, Bækvad-Hansen, M, Barchas, J D, Bass, N, Bauer, M, Beekman, A T F, Belliveau, R, Bergen, S E, Bigdeli, T B, Binder, E B, Bøen, E, Hansen, C S, Hansen, T F, Krogh, J, Pedersen, C B, Pedersen, M G, Nordentoft, M, Werge, T, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium 2020, ' The Genetics of the Mood Disorder Spectrum : Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls ', Biological Psychiatry, vol. 88, no. 2, pp. 169-184 . https://doi.org/10.1016/j.biopsych.2019.10.015
Print: 0006-3223
2020, ' The Genetics of the Mood Disorder Spectrum : Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls ', Biological psychiatry, vol. 88, no. 2, pp. 169-184 . https://doi.org/10.1016/j.biopsych.2019.10.015
Biological Psychiatry
BackgroundMood disorders (including major depressive disorder and bipolar disorder) affect 10-20% of the population. They range from brief, mild episodes to severe, incapacitating conditions that markedly impact lives. Despite their diagnostic distin
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https://research.vu.nl/en/publications/27d723ef-6f1b-4afb-a2ff-338058b3e20b
https://research.vu.nl/en/publications/27d723ef-6f1b-4afb-a2ff-338058b3e20b
Autor:
Glanville, Kylie P, Coleman, Jonathan R I, Binder, Elisabeth B, Hall, Lynsey S, Hansen, Christine Søholm, Hansen, Thomas F, Herms, Stefan, Hickie, Ian B, Hoffmann, Per, Homuth, Georg, Horn, Carsten, Hottenga, Jouke-Jan, Hougaard, David M, Blackwood, Douglas H R, Howard, David M, Ising, Marcus, Jansen, Rick, Jones, Ian, Jones, Lisa A, Jorgenson, Eric, Knowles, James A, Kohane, Isaac S, Kraft, Julia, Kretzschmar, Warren W, Boomsma, Dorret I, Kutalik, Zoltán, Li, Yihan, Lind, Penelope A, MacIntyre, Donald J, MacKinnon, Dean F, Maier, Robert M, Maier, Wolfgang, Marchini, Jonathan, Mbarek, Hamdi, McGrath, Patrick, Buttenschøn, Henriette N, McGuffin, Peter, Medland, Sarah E, Mehta, Divya, Middeldorp, Christel M, Mihailov, Evelin, Milaneschi, Yuri, Milani, Lili, Mondimore, Francis M, Montgomery, Grant W, Mostafavi, Sara, Colodro-Conde, Lucía, Mullins, Niamh, Nauck, Matthias, Ng, Bernard, Nivard, Michel G, Nyholt, Dale R, O'Reilly, Paul F, Oskarsson, Hogni, Owen, Michael J, Painter, Jodie N, Pedersen, Carsten Bøcker, Dannlowski, Udo, Pedersen, Marianne Giørtz, Peterson, Roseann E, Pettersson, Erik, Peyrot, Wouter J, Pistis, Giorgio, Posthuma, Danielle, Quiroz, Jorge A, Qvist, Per, Rice, John P, Riley, Brien P, Direk, Nese, Rivera, Margarita, Mirza, Saira Saeed, Schoevers, Robert, Schulte, Eva C, Shen, Ling, Shi, Jianxin, Shyn, Stanley I, Sigurdsson, Engilbert, Sinnamon, Grant C B, Smit, Johannes H, Dunn, Erin C, Smith, Daniel J, Stefansson, Hreinn, Steinberg, Stacy, Streit, Fabian, Strohmaier, Jana, Tansey, Katherine E, Teismann, Henning, Teumer, Alexander, Thompson, Wesley, Thomson, Pippa A, Forstner, Andreas J, Thorgeirsson, Thorgeir E, Traylor, Matthew, Treutlein, Jens, Trubetskoy, Vassily, Uitterlinden, Andrés G, Umbricht, Daniel, Van der Auwera, Sandra, van Hemert, Albert M, Viktorin, Alexander, Visscher, Peter M, de Geus, Eco J C, Wang, Yunpeng, Webb, Bradley T, Weinsheimer, Shantel Marie, Wellmann, Jürgen, Willemsen, Gonneke, Witt, Stephanie H, Wu, Yang, Xi, Hualin S, Yang, Jian, Zhang, Futao, Hanscombe, Ken B, Grabe, Hans J, Arolt, Volker, Baune, Bernhard T, Berger, Klaus, Cichon, Sven, de Geus, E. J. C., DePaulo, J Raymond, Domenici, Enrico, Domschke, Katharina, Hamilton, Steven P, Esko, Tõnu, Hayward, Caroline, Heath, Andrew C, Kendler, Kenneth S, Kloiber, Stefan, Lewis, Glyn, Li, Qingqin S, Lucae, Susanne, Madden, Pamela Af, Magnusson, Patrik K, Martin, Nicholas G, McIntosh, Andrew M, Metspalu, Andres, Mors, Ole, Mortensen, Preben Bo, Müller-Myhsok, Bertram, Nordentoft, Merete, Nöthen, Markus M, O'Donovan, Michael C, Paciga, Sara A, Pedersen, Nancy L, Penninx, Brenda W J H, Perlis, Roy H, Porteous, David J, Potash, James B, Preisig, Martin, Rietschel, Marcella, Schaefer, Catherine, Schulze, Thomas G, Smoller, Jordan W, Stefansson, Kari, Tiemeier, Henning, Uher, Rudolf, Völzke, Henry, Weissman, Myrna M, Werge, Thomas, Lewis, Cathryn M, Levinson, Douglas F, Breen, Gerome, Børglum, Anders D, Sullivan, Patrick F, Euesden, Jack, Choi, Shing Wan, Ripke, Stephan, Purves, Kirstin L, Consortium, Major Depressive Disorder Working Group of the Psychiatric Genomics, Wray, Naomi R, Mattheisen, Manuel, Trzaskowski, Maciej, Byrne, Enda M, Abdellaoui, Abdel, Adams, Mark J, Agerbo, Esben, Air, Tracy M, Andlauer, Till F M, Bacanu, Silviu-Alin, Bækvad-Hansen, Marie, Beekman, Aartjan T F, Bigdeli, Tim B, Bryois, Julien, Bybjerg-Grauholm, Jonas, Cai, Na, Castelao, Enrique, Christensen, Jane Hvarregaard, Clarke, Toni-Kim, Couvy-Duchesne, Baptiste, Craddock, Nick, Crawford, Gregory E, Davies, Gail, Deary, Ian J, Degenhardt, Franziska, Derks, Eske M, Dolan, Conor V, Eley, Thalia C, Escott-Price, Valentina, Hassan Kiadeh, Farnush Farhadi, Finucane, Hilary K, Foo, Jerome C, Frank, Josef, Gaspar, Héléna A, Gill, Michael, Goes, Fernando S, Gordon, Scott D, Grove, Jakob
Publikováno v:
Biological psychiatry, 87(5), 419-430. Elsevier USA
2019, ' Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression ', Biological Psychiatry . https://doi.org/10.1016/j.biopsych.2019.06.031
Biological psychiatry, vol. 87, no. 5, pp. 419-430
Glanville, K P, Lewis, C M, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Abdellaoui, A, Dolan, C V, Hottenga, J J, Jansen, R, Mbarek, H, Middeldorp, C M, Milaneschi, Y, Nivard, M G, Peyrot, W J, Posthuma, D & Willemsen, G 2020, ' Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression ', Biological Psychiatry, vol. 87, no. 5, pp. 419-430 . https://doi.org/10.1016/j.biopsych.2019.06.031
Biological Psychiatry, 87(5), 419-430. Elsevier USA
Biological Psychiatry
Online: 0006-3223
Biological Psychiatry, 87(5), 419-430. Elsevier Inc.
Glanville, K P, Coleman, J R I, Hanscombe, K B, Euesden, J, Choi, S W, Purves, K L, Breen, G, Air, T M, Andlauer, T F M, Baune, B T, Binder, E B, Blackwood, D H R, Boomsma, D I, Buttenschøn, H N, Colodro-Conde, L, Dannlowski, U, Direk, N, Dunn, E C, Forstner, A J, de Geus, E J C, Grabe, H J, Hamilton, S P, Jones, I, Jones, L A, Knowles, J A, Kutalik, Z, Levinson, D F, Lewis, G, Lind, P A, Lucae, S, Magnusson, P K, McGuffin, P, McIntosh, A M, Milaneschi, Y, Mors, O, Mostafavi, S, Müller-Myhsok, B, Pedersen, N L, Penninx, B W J H, Potash, J B, Preisig, M, Ripke, S, Shi, J, Shyn, S I, Smoller, J W, Streit, F, Sullivan, P F, Tiemeier, H, Uher, R, Van der Auwera, S & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium 2020, ' Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression ', Biological Psychiatry, vol. 87, no. 5, pp. 419-430 . https://doi.org/10.1016/j.biopsych.2019.06.031
Biological Psychiatry, 87(5), 419-430. ELSEVIER SCIENCE INC
Glanville, K P, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Coleman, J R I, Hanscombe, K B, Euesden, J, Choi, S W, Purves, K L, Breen, G, Air, T M, Andlauer, T F M, Baune, B T, Binder, E B, Blackwood, D H R, Boomsma, D I, Buttenschøn, H N, Colodro-Conde, L, Dannlowski, U, Direk, N, Dunn, E C, Forstner, A J, de Geus, E J C, Grabe, H J, Hamilton, S P, Jones, I, Jones, L A, Knowles, J A, Kutalik, Z, Levinson, D F, Lewis, G, Lind, P A, Lucae, S, Magnusson, P K, McGuffin, P, McIntosh, A M, Milaneschi, Y, Mors, O, Mostafavi, S, Müller-Myhsok, B, Pedersen, N L, Penninx, B W J H, Potash, J B, Preisig, M, Ripke, S, Beekman, A T F, Jansen, R, Middeldorp, C M, Peyrot, W J, Posthuma, D, Schoevers, R, Smit, J H, de Geus, E J C, Weissman, M M & O'Reilly, P F 2020, ' Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression ', Biological Psychiatry, vol. 87, no. 5, pp. 419-430 . https://doi.org/10.1016/j.biopsych.2019.06.031
Biological psychiatry 87(5), 419-430 (2020). doi:10.1016/j.biopsych.2019.06.031
Glanville, K P, Coleman, J R I, Hanscombe, K B, Euesden, J, Choi, S W, Purves, K L, Breen, G, Air, T M, Andlauer, T F M, Baune, B T, Binder, E B, Blackwood, D H R, Boomsma, D I, Buttenschøn, H N, Colodro-Conde, L, Dannlowski, U, Direk, N, Dunn, E C, Forstner, A J, de Geus, E J C, Grabe, H J, Hamilton, S P, Jones, I, Jones, L A, Knowles, J A, Kutalik, Z, Levinson, D F, Lewis, G, Lind, P A, Lucae, S, Magnusson, P K, McGuffin, P, McIntosh, A M, Milaneschi, Y, Mors, O, Mostafavi, S, Müller-Myhsok, B, Pedersen, N L, Penninx, B W J H, Potash, J B, Preisig, M, Ripke, S, Shi, J, Bækvad-Hansen, M, Hansen, C S, Hansen, T F, Pedersen, C B, Pedersen, M G, Nordentoft, M, Werge, T & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium 2020, ' Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression ', Biological Psychiatry, vol. 87, no. 5, pp. 419-430 . https://doi.org/10.1016/j.biopsych.2019.06.031
Glanville, K P, Coleman, J R I, Hanscombe, K B, Euesden, J, Choi, S W, Purves, K, Breen, G, Air, T M, Andlauer, T M F, Baune, B T, Binder, E B, Blackwood, D H R, Boomsma, D I, Buttenschøn, H N, Colodro-Conde, L, Dannlowski, U, Direk, N, Dunn, E C, Forstner, A J, de Geus, E J C, Grabe, H J, Hamilton, S P, Jones, I, Jones, L A, Knowles, J A, Kutalik, Z, Levinson, D F, Lewis, G, Lind, P A, Lucae, S, Lucae, S, Magnusson., P K E, McGuffin, P, McIntosh, A, Milaneschi, Y, Lewis, C M, Mostafavi, S, Muller-Myhsok, B, Pedersen, N L, Penninx, B W, Potash, J B, Preisig, M, Ripke, S, Shi, J, Shyn, S I, Smoller, J W, Streit, F, Sullivan, P F, Tiemeier, H, Uher, R, der Auwera, S V, Weissman, M M, O'Reilly, P F & Lewis, C M 2020, ' Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression ', Biological psychiatry, vol. 87, no. 5, pp. 419-430 . https://doi.org/10.1016/j.biopsych.2019.06.031
2019, ' Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression ', Biological Psychiatry . https://doi.org/10.1016/j.biopsych.2019.06.031
Biological psychiatry, vol. 87, no. 5, pp. 419-430
Glanville, K P, Lewis, C M, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Abdellaoui, A, Dolan, C V, Hottenga, J J, Jansen, R, Mbarek, H, Middeldorp, C M, Milaneschi, Y, Nivard, M G, Peyrot, W J, Posthuma, D & Willemsen, G 2020, ' Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression ', Biological Psychiatry, vol. 87, no. 5, pp. 419-430 . https://doi.org/10.1016/j.biopsych.2019.06.031
Biological Psychiatry, 87(5), 419-430. Elsevier USA
Biological Psychiatry
Online: 0006-3223
Biological Psychiatry, 87(5), 419-430. Elsevier Inc.
Glanville, K P, Coleman, J R I, Hanscombe, K B, Euesden, J, Choi, S W, Purves, K L, Breen, G, Air, T M, Andlauer, T F M, Baune, B T, Binder, E B, Blackwood, D H R, Boomsma, D I, Buttenschøn, H N, Colodro-Conde, L, Dannlowski, U, Direk, N, Dunn, E C, Forstner, A J, de Geus, E J C, Grabe, H J, Hamilton, S P, Jones, I, Jones, L A, Knowles, J A, Kutalik, Z, Levinson, D F, Lewis, G, Lind, P A, Lucae, S, Magnusson, P K, McGuffin, P, McIntosh, A M, Milaneschi, Y, Mors, O, Mostafavi, S, Müller-Myhsok, B, Pedersen, N L, Penninx, B W J H, Potash, J B, Preisig, M, Ripke, S, Shi, J, Shyn, S I, Smoller, J W, Streit, F, Sullivan, P F, Tiemeier, H, Uher, R, Van der Auwera, S & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium 2020, ' Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression ', Biological Psychiatry, vol. 87, no. 5, pp. 419-430 . https://doi.org/10.1016/j.biopsych.2019.06.031
Biological Psychiatry, 87(5), 419-430. ELSEVIER SCIENCE INC
Glanville, K P, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Coleman, J R I, Hanscombe, K B, Euesden, J, Choi, S W, Purves, K L, Breen, G, Air, T M, Andlauer, T F M, Baune, B T, Binder, E B, Blackwood, D H R, Boomsma, D I, Buttenschøn, H N, Colodro-Conde, L, Dannlowski, U, Direk, N, Dunn, E C, Forstner, A J, de Geus, E J C, Grabe, H J, Hamilton, S P, Jones, I, Jones, L A, Knowles, J A, Kutalik, Z, Levinson, D F, Lewis, G, Lind, P A, Lucae, S, Magnusson, P K, McGuffin, P, McIntosh, A M, Milaneschi, Y, Mors, O, Mostafavi, S, Müller-Myhsok, B, Pedersen, N L, Penninx, B W J H, Potash, J B, Preisig, M, Ripke, S, Beekman, A T F, Jansen, R, Middeldorp, C M, Peyrot, W J, Posthuma, D, Schoevers, R, Smit, J H, de Geus, E J C, Weissman, M M & O'Reilly, P F 2020, ' Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression ', Biological Psychiatry, vol. 87, no. 5, pp. 419-430 . https://doi.org/10.1016/j.biopsych.2019.06.031
Biological psychiatry 87(5), 419-430 (2020). doi:10.1016/j.biopsych.2019.06.031
Glanville, K P, Coleman, J R I, Hanscombe, K B, Euesden, J, Choi, S W, Purves, K L, Breen, G, Air, T M, Andlauer, T F M, Baune, B T, Binder, E B, Blackwood, D H R, Boomsma, D I, Buttenschøn, H N, Colodro-Conde, L, Dannlowski, U, Direk, N, Dunn, E C, Forstner, A J, de Geus, E J C, Grabe, H J, Hamilton, S P, Jones, I, Jones, L A, Knowles, J A, Kutalik, Z, Levinson, D F, Lewis, G, Lind, P A, Lucae, S, Magnusson, P K, McGuffin, P, McIntosh, A M, Milaneschi, Y, Mors, O, Mostafavi, S, Müller-Myhsok, B, Pedersen, N L, Penninx, B W J H, Potash, J B, Preisig, M, Ripke, S, Shi, J, Bækvad-Hansen, M, Hansen, C S, Hansen, T F, Pedersen, C B, Pedersen, M G, Nordentoft, M, Werge, T & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium 2020, ' Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression ', Biological Psychiatry, vol. 87, no. 5, pp. 419-430 . https://doi.org/10.1016/j.biopsych.2019.06.031
Glanville, K P, Coleman, J R I, Hanscombe, K B, Euesden, J, Choi, S W, Purves, K, Breen, G, Air, T M, Andlauer, T M F, Baune, B T, Binder, E B, Blackwood, D H R, Boomsma, D I, Buttenschøn, H N, Colodro-Conde, L, Dannlowski, U, Direk, N, Dunn, E C, Forstner, A J, de Geus, E J C, Grabe, H J, Hamilton, S P, Jones, I, Jones, L A, Knowles, J A, Kutalik, Z, Levinson, D F, Lewis, G, Lind, P A, Lucae, S, Lucae, S, Magnusson., P K E, McGuffin, P, McIntosh, A, Milaneschi, Y, Lewis, C M, Mostafavi, S, Muller-Myhsok, B, Pedersen, N L, Penninx, B W, Potash, J B, Preisig, M, Ripke, S, Shi, J, Shyn, S I, Smoller, J W, Streit, F, Sullivan, P F, Tiemeier, H, Uher, R, der Auwera, S V, Weissman, M M, O'Reilly, P F & Lewis, C M 2020, ' Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression ', Biological psychiatry, vol. 87, no. 5, pp. 419-430 . https://doi.org/10.1016/j.biopsych.2019.06.031
Background\ud \ud The prevalence of depression is higher in individuals with autoimmune diseases, but the mechanisms underlying the observed comorbidities are unknown. Shared genetic etiology is a plausible explanation for the overlap, and in this st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9782d526132cb79104890e64504600e7
https://pure.amc.nl/en/publications/classical-human-leukocyte-antigen-alleles-and-c4-haplotypes-are-not-significantly-associated-with-depression(84178d87-a771-42e3-acf1-26f4c561ab32).html
https://pure.amc.nl/en/publications/classical-human-leukocyte-antigen-alleles-and-c4-haplotypes-are-not-significantly-associated-with-depression(84178d87-a771-42e3-acf1-26f4c561ab32).html
Autor:
Coleman, Jonathan RI, Peyrot, Wouter J, Purves, Kirstin L, Davis, Katrina AS, Rayner, Christopher, Choi, Shing Wan, Hubel, Christopher, Gaspar, Helena A, Kan, Carol, Van der Auwera, Sandra, Adams, Mark James, Lyall, Donald M, Choi, Karmel W, Dunn, Erin C, Vassos, Evangelos, Danese, Andrea, Maughan, Barbara, Grabe, Hans J, Lewis, Cathryn M, O'Reilly, Paul F, McIntosh, Andrew M, Smith, Daniel J, Wray, Naomi R, Hotopf, Matthew, Eley, Thalia C, Breen, Gerome, Ripke, Stephan, Mattheisen, Manuel, Trzaskowski, Maciej, Byrne, Enda M, Abdellaoui, Abdel, Adams, Mark J, Agerbo, Esben, Air, Tracy M, Andlauer, Till FM, Bacanu, Silviu-Alin, Baekvad-Hansen, Marie, Beekman, Aartjan TF, Bigdeli, Tim B, Binder, Elisabeth B, Bryois, Julien, Buttenschon, Henriette N, Bybjerg-Grauholm, Jonas, Cai, Na, Castelao, Enrique, Christensen, Jane Hvarregaard, Clarke, Toni-Kim, Colodro-Conde, Lucia, Couvy-Duchesne, Baptiste, Craddock, Nick, Crawford, Gregory E, Davies, Gail, Deary, Ian J, Degenhardt, Franziska, Derks, Eske M, Direk, Nese, Dolan, Conor V, Escott-Price, Valentina, Kiadeh, Farnush Farhadi Hassan, Finucane, Hilary K, Foo, Jerome C, Forstner, Andreas J, Frank, Josef, Gill, Michael, Goes, Fernando S, Gordon, Scott D, Grove, Jakob, Hall, Lynsey S, Hansen, Christine Soholm, Hansen, Thomas F, Herms, Stefan, Hickie, Ian B, Hoffmann, Per, Homuth, Georg, Horn, Carsten, Hottenga, Jouke-Jan, Hougaard, David M, Howard, David M, Ising, Marcus, Jansen, Rick, Jones, Ian, Jones, Lisa A, Jorgenson, Eric, Knowles, James A, Kohane, Isaac S, Kraft, Julia, Kretzschmar, Warren W, Kutalik, Zoltan, Li, Yihan, Lind, Penelope A, MacIntyre, Donald J, MacKinnon, Dean F, Maier, Robert M, Maier, Wolfgang, Marchini, Jonathan, Mbarek, Hamdi, McGrath, Patrick, McGuffin, Peter, Medland, Sarah E, Mehta, Divya, Middeldorp, Christel M, Mihailov, Evelin, Milaneschi, Yuri, Milani, Lili, Mondimore, Francis M, Montgomery, Grant W, Mostafavi, Sara, Mullins, Niamh, Nauck, Matthias, Ng, Bernard, Nivard, Michel G, Nyholt, Dale R, Oskarsson, Hogni, Owen, Michael J, Painter, Jodie N, Pedersen, Carsten Bocker, Pedersen, Marianne Giortz, Peterson, Roseann E, Pettersson, Erik, Pistis, Giorgio, Posthuma, Danielle, Quiroz, Jorge A, Qvist, Per, Rice, John P, Riley, Brien P, Rivera, Margarita, Mirza, Saira Saeed, Schoevers, Robert, Schulte, Eva C, Shen, Ling, Shi, Jianxin, Shyn, Stanley I, Sigurdsson, Engilbert, Sinnamon, Grant CB, Smit, Johannes H, Stefansson, Hreinn, Steinberg, Stacy, Streit, Fabian, Strohmaier, Jana, Tansey, Katherine E, Teismann, Henning, Teumer, Alexander, Thompson, Wesley, Thomson, Pippa A, Thorgeirsson, Thorgeir E, Traylor, Matthew, Treutlein, Jens, Trubetskoy, Vassily, Uitterlinden, Andres G, Umbricht, Daniel, van Hemert, Albert M, Viktorin, Alexander, Visscher, Peter M, Wang, Yunpeng, Webb, Bradley T, Weinsheimer, Shantel Marie, Wellmann, Jurgen, Willemsen, Gonneke, Witt, Stephanie H, Wu, Yang, Xi, Hualin S, Yang, Jian, Zhang, Futao, Arolt, Volker, Baune, Bernhard T, Berger, Klaus, Boomsma, Dorret I, Cichon, Sven, Dannlowski, Udo, de Geus, EJC, DePaulo, J Raymond, Domenici, Enrico, Domschke, Katharina, Esko, Tonu, Hamilton, Steven P, Hayward, Caroline, Heath, Andrew C, Kendler, Kenneth S, Kloiber, Stefan, Lewis, Glyn, Li, Qingqin S, Lucae, Susanne, Madden, Pamela AF, Magnusson, Patrik K, Martin, Nicholas G, Metspalu, Andres, Mors, Ole, Mortensen, Preben Bo, Mueller-Myhsok, Bertram, Nordentoft, Merete, Noethen, Markus M, O'Donovan, Michael C, Paciga, Sara A, Pedersen, Nancy L, Penninx, Brenda WJH, Perlis, Roy H, Porteous, David J, Potash, James B, Preisig, Martin, Rietschel, Marcella, Schaefer, Catherine, Schulze, Thomas G, Smoller, Jordan W, Stefansson, Kari, Tiemeier, Henning, Uher, Rudolf, Volzke, Henry, Weissman, Myrna M, Werge, Thomas, Levinson, Douglas F, Borglum, Anders D, Sullivan, Patrick F, Consortium, Psychiat Genomics
Publikováno v:
Coleman, J R I, Peyrot, W J, Purves, K, Davis, K A S, Rayner, C, Choi, S W, Huebel, C, Gaspar, H A, Kan, C, der Auwera, S V, Adams, M J, Lyall, D, Choi, K W, Dunn, E C, Vassos, E, Danese, A, Maughan, B, Grabe, H J, Lewis, C M, O'Reilly, P F, McIntosh, A M, Smith, D J, Wray, N R, Hotopf, M, Eley, T & Breen, G & Howard, D 2020, ' Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank ', Molecular Psychiatry, vol. 25, no. 7, pp. 1430-1446 . https://doi.org/10.1038/s41380-019-0546-6
Molecular Psychiatry, 25, 1430-1446. NATURE PUBLISHING GROUP
Molecular psychiatry
Coleman, J R I & Adams, M J & McIntosh, A 2020, ' Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank ', Molecular Psychiatry . https://doi.org/10.1038/s41380-019-0546-6
MOLECULAR PSYCHIATRY
Molecular Psychiatry, 25(7), 1430-1446. Nature Publishing Group
Coleman, J R I, Peyrot, W J, Purves, K L, Davis, K A S, Rayner, C, Choi, S W, Hübel, C, Gaspar, H A, Kan, C, Van der Auwera, S, Adams, M J, Lyall, D M, Choi, K W, Wray, N R, Ripke, S, Mattheisen, M, Trzaskowski, M, Byrne, E M, Abdellaoui, A, Adams, M J, Agerbo, E, Air, T M, Andlauer, T F M, Bacanu, S A, Bækvad-Hansen, M, Beekman, A T F, Bigdeli, T B, Binder, E B, Bryois, J, Buttenschøn, H N, Bybjerg-Grauholm, J, Cai, N, Castelao, E, Christensen, J H, Clarke, T K, Coleman, J R I, Colodro-Conde, L, Couvy-Duchesne, B, Craddock, N, Crawford, G E, Davies, G, Deary, I J, Degenhardt, F, Derks, E M, Direk, N, Dolan, C V, Dunn, E C, Eley, T C, Escott-Price, V, Kiadeh, F F H, Finucane, H K, Foo, J C, Forstner, A J, Frank, J, Gaspar, H A, Gill, M, Goes, F S, Gordon, S D, Grove, J, Hall, L S, Hansen, C S, Hansen, T F, Herms, S, Hickie, I B, Hoffmann, P, Homuth, G, Horn, C, Hottenga, J J, Hougaard, D M, Howard, D M, Ising, M, Jansen, R, Jones, I, Jones, L A, Jorgenson, E, Knowles, J A, Kohane, I S, Kraft, J, Kretzschmar, W W, Kutalik, Z, Li, Y, Lind, P A, MacIntyre, D J, MacKinnon, D F, Maier, R M, Maier, W, Marchini, J, Mbarek, H, McGrath, P, McGuffin, P, Medland, S E, Mehta, D, Middeldorp, C M, Mihailov, E, Milaneschi, Y, Milani, L, Mondimore, F M, Montgomery, G W, Mostafavi, S, Mullins, N, Nauck, M, Ng, B, Nivard, M G, Nyholt, D R, O’Reilly, P F, Oskarsson, H, Owen, M J, Painter, J N, Pedersen, C B, Pedersen, M G, Peterson, R E, Pettersson, E, Peyrot, W J, Pistis, G, Posthuma, D, Quiroz, J A, Qvist, P, Rice, J P, Riley, B P, Rivera, M, Mirza, S S, Schoevers, R, Schulte, E C, Shen, L, Shi, J, Shyn, S I, Sigurdsson, E, Sinnamon, G C B, Smit, J H, Smith, D J, Stefansson, H, Steinberg, S, Streit, F, Strohmaier, J, Tansey, K E, Teismann, H, Teumer, A, Thompson, W, Thomson, P A, Thorgeirsson, T E, Traylor, M, Treutlein, J, Trubetskoy, V, Uitterlinden, A G, Umbricht, D, Van der Auwera, S, van Hemert, A M, Viktorin, A, Visscher, P M, Wang, Y, Webb, B T, Weinsheimer, S M, Wellmann, J, Willemsen, G, Witt, S H, Wu, Y, Xi, H S, Yang, J, Zhang, F, Arolt, V, Baune, B T, Berger, K, Boomsma, D I, Cichon, S, Dannlowski, U, de Geus, E J C, DePaulo, J R, Domenici, E, Domschke, K, Esko, T, Grabe, H J, Hamilton, S P, Hayward, C, Heath, A C, Kendler, K S, Kloiber, S, Lewis, G, Li, Q S, Lucae, S, Madden, P A F, Magnusson, P K, Martin, N G, McIntosh, A M, Metspalu, A, Mors, O, Mortensen, P B, Müller-Myhsok, B, Nordentoft, M, Nöthen, M M, O’Donovan, M C, Paciga, S A, Pedersen, N L, Penninx, B W J H, Perlis, R H, Porteous, D J, Potash, J B, Preisig, M, Rietschel, M, Schaefer, C, Schulze, T G, Smoller, J W, Stefansson, K, Tiemeier, H, Uher, R, Völzke, H, Weissman, M M, Werge, T, Lewis, C M, Levinson, D F, Breen, G, Børglum, A D, Sullivan, P F, Dunn, E C, Vassos, E, Danese, A, Maughan, B, Grabe, H J, Lewis, C M, O’Reilly, P F, McIntosh, A M, Smith, D J, Wray, N R, Hotopf, M, Eley, T C, Breen, G & on the behalf of Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium 2020, ' Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank ', Molecular Psychiatry, vol. 25, no. 7, pp. 1430-1446 . https://doi.org/10.1038/s41380-019-0546-6
Coleman, J R I, Peyrot, W J, Purves, K L, Davis, K A S, Rayner, C, Choi, S W, Hubel, C, Gaspar, H A, Kan, C, Van der Auwera, S, Adams, M J, Lyall, D M, Choi, K W, Psychiat Genomics Consortium, Dunn, E C, Vassos, E, Danese, A, Maughan, B, Grabe, H J, Lewis, C M, O'Reilly, P F, McIntosh, A M, Smith, D J, Wray, N R, Hotopf, M, Eley, T C & Breen, G 2020, ' Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank ', Molecular Psychiatry, vol. 25, no. 7, pp. 1430-1446 . https://doi.org/10.1038/s41380-019-0546-6
Coleman, J R I, Peyrot, W J, Purves, K L, Davis, K A S, Rayner, C, Choi, S W, Hübel, C, Gaspar, H A, Kan, C, Van der Auwera, S, Adams, M J, Lyall, D M, Choi, K W, Wray, N R, Ripke, S, Mattheisen, M, Trzaskowski, M, Byrne, E M, Abdellaoui, A, Adams, M J, Agerbo, E, Air, T M, Andlauer, T F M, Bacanu, S A, Bækvad-Hansen, M, Beekman, A T F, Bigdeli, T B, Binder, E B, Bryois, J, Buttenschøn, H N, Bybjerg-Grauholm, J, Cai, N, Castelao, E, Christensen, J H, Clarke, T K, Coleman, J R I, Colodro-Conde, L, Couvy-Duchesne, B, Craddock, N, Crawford, G E, Davies, G, Deary, I J, Degenhardt, F, Derks, E M, Hansen, C S, Hansen, T F, Pedersen, C B, Pedersen, M G, Nordentoft, M, Werge, T & on the behalf of Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium 2020, ' Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank ', Molecular Psychiatry, vol. 25, pp. 1430-1446 . https://doi.org/10.1038/s41380-019-0546-6
Molecular psychiatry, 25(7), 1430-1446. Nature Publishing Group
Coleman, J R I, Breen, G, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Abdellaoui, A, Dolan, C V, Hottenga, J J, Mbarek, H, Middeldorp, C M, Nivard, M G, Willemsen, G, Boomsma, D I, de Geus, E J C, Beekman, A T F, Jansen, R, Milaneschi, Y, Smit, J H, W J H Penninx, B & Posthuma, D 2020, ' Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank ', Molecular Psychiatry, vol. 25, no. 7, pp. 1430-1446 . https://doi.org/10.1038/s41380-019-0546-6
Molecular psychiatry, vol. 25, no. 7, pp. 1430-1446
Molecular Psychiatry, 25, 1430-1446. NATURE PUBLISHING GROUP
Molecular psychiatry
Coleman, J R I & Adams, M J & McIntosh, A 2020, ' Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank ', Molecular Psychiatry . https://doi.org/10.1038/s41380-019-0546-6
MOLECULAR PSYCHIATRY
Molecular Psychiatry, 25(7), 1430-1446. Nature Publishing Group
Coleman, J R I, Peyrot, W J, Purves, K L, Davis, K A S, Rayner, C, Choi, S W, Hübel, C, Gaspar, H A, Kan, C, Van der Auwera, S, Adams, M J, Lyall, D M, Choi, K W, Wray, N R, Ripke, S, Mattheisen, M, Trzaskowski, M, Byrne, E M, Abdellaoui, A, Adams, M J, Agerbo, E, Air, T M, Andlauer, T F M, Bacanu, S A, Bækvad-Hansen, M, Beekman, A T F, Bigdeli, T B, Binder, E B, Bryois, J, Buttenschøn, H N, Bybjerg-Grauholm, J, Cai, N, Castelao, E, Christensen, J H, Clarke, T K, Coleman, J R I, Colodro-Conde, L, Couvy-Duchesne, B, Craddock, N, Crawford, G E, Davies, G, Deary, I J, Degenhardt, F, Derks, E M, Direk, N, Dolan, C V, Dunn, E C, Eley, T C, Escott-Price, V, Kiadeh, F F H, Finucane, H K, Foo, J C, Forstner, A J, Frank, J, Gaspar, H A, Gill, M, Goes, F S, Gordon, S D, Grove, J, Hall, L S, Hansen, C S, Hansen, T F, Herms, S, Hickie, I B, Hoffmann, P, Homuth, G, Horn, C, Hottenga, J J, Hougaard, D M, Howard, D M, Ising, M, Jansen, R, Jones, I, Jones, L A, Jorgenson, E, Knowles, J A, Kohane, I S, Kraft, J, Kretzschmar, W W, Kutalik, Z, Li, Y, Lind, P A, MacIntyre, D J, MacKinnon, D F, Maier, R M, Maier, W, Marchini, J, Mbarek, H, McGrath, P, McGuffin, P, Medland, S E, Mehta, D, Middeldorp, C M, Mihailov, E, Milaneschi, Y, Milani, L, Mondimore, F M, Montgomery, G W, Mostafavi, S, Mullins, N, Nauck, M, Ng, B, Nivard, M G, Nyholt, D R, O’Reilly, P F, Oskarsson, H, Owen, M J, Painter, J N, Pedersen, C B, Pedersen, M G, Peterson, R E, Pettersson, E, Peyrot, W J, Pistis, G, Posthuma, D, Quiroz, J A, Qvist, P, Rice, J P, Riley, B P, Rivera, M, Mirza, S S, Schoevers, R, Schulte, E C, Shen, L, Shi, J, Shyn, S I, Sigurdsson, E, Sinnamon, G C B, Smit, J H, Smith, D J, Stefansson, H, Steinberg, S, Streit, F, Strohmaier, J, Tansey, K E, Teismann, H, Teumer, A, Thompson, W, Thomson, P A, Thorgeirsson, T E, Traylor, M, Treutlein, J, Trubetskoy, V, Uitterlinden, A G, Umbricht, D, Van der Auwera, S, van Hemert, A M, Viktorin, A, Visscher, P M, Wang, Y, Webb, B T, Weinsheimer, S M, Wellmann, J, Willemsen, G, Witt, S H, Wu, Y, Xi, H S, Yang, J, Zhang, F, Arolt, V, Baune, B T, Berger, K, Boomsma, D I, Cichon, S, Dannlowski, U, de Geus, E J C, DePaulo, J R, Domenici, E, Domschke, K, Esko, T, Grabe, H J, Hamilton, S P, Hayward, C, Heath, A C, Kendler, K S, Kloiber, S, Lewis, G, Li, Q S, Lucae, S, Madden, P A F, Magnusson, P K, Martin, N G, McIntosh, A M, Metspalu, A, Mors, O, Mortensen, P B, Müller-Myhsok, B, Nordentoft, M, Nöthen, M M, O’Donovan, M C, Paciga, S A, Pedersen, N L, Penninx, B W J H, Perlis, R H, Porteous, D J, Potash, J B, Preisig, M, Rietschel, M, Schaefer, C, Schulze, T G, Smoller, J W, Stefansson, K, Tiemeier, H, Uher, R, Völzke, H, Weissman, M M, Werge, T, Lewis, C M, Levinson, D F, Breen, G, Børglum, A D, Sullivan, P F, Dunn, E C, Vassos, E, Danese, A, Maughan, B, Grabe, H J, Lewis, C M, O’Reilly, P F, McIntosh, A M, Smith, D J, Wray, N R, Hotopf, M, Eley, T C, Breen, G & on the behalf of Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium 2020, ' Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank ', Molecular Psychiatry, vol. 25, no. 7, pp. 1430-1446 . https://doi.org/10.1038/s41380-019-0546-6
Coleman, J R I, Peyrot, W J, Purves, K L, Davis, K A S, Rayner, C, Choi, S W, Hubel, C, Gaspar, H A, Kan, C, Van der Auwera, S, Adams, M J, Lyall, D M, Choi, K W, Psychiat Genomics Consortium, Dunn, E C, Vassos, E, Danese, A, Maughan, B, Grabe, H J, Lewis, C M, O'Reilly, P F, McIntosh, A M, Smith, D J, Wray, N R, Hotopf, M, Eley, T C & Breen, G 2020, ' Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank ', Molecular Psychiatry, vol. 25, no. 7, pp. 1430-1446 . https://doi.org/10.1038/s41380-019-0546-6
Coleman, J R I, Peyrot, W J, Purves, K L, Davis, K A S, Rayner, C, Choi, S W, Hübel, C, Gaspar, H A, Kan, C, Van der Auwera, S, Adams, M J, Lyall, D M, Choi, K W, Wray, N R, Ripke, S, Mattheisen, M, Trzaskowski, M, Byrne, E M, Abdellaoui, A, Adams, M J, Agerbo, E, Air, T M, Andlauer, T F M, Bacanu, S A, Bækvad-Hansen, M, Beekman, A T F, Bigdeli, T B, Binder, E B, Bryois, J, Buttenschøn, H N, Bybjerg-Grauholm, J, Cai, N, Castelao, E, Christensen, J H, Clarke, T K, Coleman, J R I, Colodro-Conde, L, Couvy-Duchesne, B, Craddock, N, Crawford, G E, Davies, G, Deary, I J, Degenhardt, F, Derks, E M, Hansen, C S, Hansen, T F, Pedersen, C B, Pedersen, M G, Nordentoft, M, Werge, T & on the behalf of Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium 2020, ' Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank ', Molecular Psychiatry, vol. 25, pp. 1430-1446 . https://doi.org/10.1038/s41380-019-0546-6
Molecular psychiatry, 25(7), 1430-1446. Nature Publishing Group
Coleman, J R I, Breen, G, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Abdellaoui, A, Dolan, C V, Hottenga, J J, Mbarek, H, Middeldorp, C M, Nivard, M G, Willemsen, G, Boomsma, D I, de Geus, E J C, Beekman, A T F, Jansen, R, Milaneschi, Y, Smit, J H, W J H Penninx, B & Posthuma, D 2020, ' Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank ', Molecular Psychiatry, vol. 25, no. 7, pp. 1430-1446 . https://doi.org/10.1038/s41380-019-0546-6
Molecular psychiatry, vol. 25, no. 7, pp. 1430-1446
Depression is more frequent among individuals exposed to traumatic events. Both trauma exposure and depression are heritable. However, the relationship between these traits, including the role of genetic risk factors, is complex and poorly understood
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d4991e162bcb17808a3531fcc7d64b1
https://research.vu.nl/ws/files/121748816/Genomewide_geneenvironment_analyses_of_major_depressive_disorder_and_reported_lifetime_traumatic_experiences_in_UK_Biobank.pdf
https://research.vu.nl/ws/files/121748816/Genomewide_geneenvironment_analyses_of_major_depressive_disorder_and_reported_lifetime_traumatic_experiences_in_UK_Biobank.pdf
Autor:
Czamara, Darina, Eraslan, Gökçen, Page, Christian M., Lahti, Jari, Lahti-Pulkkinen, Marius, Hämäläinen, Esa, Kajantie, Eero, Laivuori, Hannele, Villa, Pia M., Reynolds, Rebecca M., Nystad, Wenche, Håberg, Siri E., London, Stephanie J., O’Donnell, Kieran J., Garg, Elika, Meaney, Michael J., Entringer, Sonja, Wadhwa, Pathik D., Buss, Claudia, Jones, Meaghan J., Lin, David T. S., MacIsaac, Julie L., Kobor, Michael S., Koen, Nastassja, Zar, Heather J., Koenen, Karestan C., Dalvie, Shareefa, Stein, Dan J., Kondofersky, Ivan, Müller, Nikola S., Theis, Fabian J., Wray, Naomi R., Ripke, Stephan, Mattheisen, Manuel, Trzaskowski, Maciej, Byrne, Enda M., Abdellaoui, Abdel, Adams, Mark J., Agerbo, Esben, Air, Tracy M., Andlauer, Till F. M., Bacanu, Silviu-Alin, Bækvad-Hansen, Marie, Beekman, Aartjan T. F., Bigdeli, Tim B., Blackwood, Douglas H. R., Bryois, Julien, Buttenschøn, Henriette N., Bybjerg-Grauholm, Jonas, Cai, Na, Castelao, Enrique, Christensen, Jane Hvarregaard, Clarke, Toni-Kim, Coleman, Jonathan R. I., Colodro-Conde, Lucía, Couvy-Duchesne, Baptiste, Craddock, Nick, Crawford, Gregory E., Davies, Gail, Deary, Ian J., Degenhardt, Franziska, Derks, Eske M., Direk, Nese, Dolan, Conor V., Dunn, Erin C., Eley, Thalia C., Escott-Price, Valentina, Kiadeh, Farnush Farhadi Hassan, Finucane, Hilary K., Forstner, Andreas J., Frank, Josef, Gaspar, Héléna A., Gill, Michael, Goes, Fernando S., Gordon, Scott D., Grove, Jakob, Hall, Lynsey S., Hansen, Christine Søholm, Hansen, Thomas F., Herms, Stefan, Hickie, Ian B., Hoffmann, Per, Homuth, Georg, Horn, Carsten, Hottenga, Jouke-Jan, Hougaard, David M., Ising, Marcus, Jansen, Rick, Jorgenson, Eric, Knowles, James A., Kohane, Isaac S., Kraft, Julia, Kretzschmar, Warren W., Krogh, Jesper, Kutalik, Zoltán, Li, Yihan, Lind, Penelope A., MacIntyre, Donald J., MacKinnon, Dean F., Maier, Robert M., Maier, Wolfgang, Marchini, Jonathan, Mbarek, Hamdi, McGrath, Patrick, McGuffin, Peter, Medland, Sarah E., Mehta, Divya, Middeldorp, Christel M., Mihailov, Evelin, Milaneschi, Yuri, Milani, Lili, Mondimore, Francis M., Montgomery, Grant W., Mostafavi, Sara, Mullins, Niamh, Nauck, Matthias, Ng, Bernard, Nivard, Michel G., Nyholt, Dale R., O’Reilly, Paul F., Oskarsson, Hogni, Owen, Michael J., Painter, Jodie N., Pedersen, Carsten Bøcker, Pedersen, Marianne Giørtz, Peterson, Roseann E., Pettersson, Erik, Peyrot, Wouter J., Pistis, Giorgio, Posthuma, Danielle, Quiroz, Jorge A., Qvist, Per, Rice, John P., Riley, Brien P., Rivera, Margarita, Mirza, Saira Saeed, Schoevers, Robert, Schulte, Eva C., Shen, Ling, Shi, Jianxin, Shyn, Stanley I., Sigurdsson, Engilbert, Sinnamon, Grant C. B., Smit, Johannes H., Smith, Daniel J., Stefansson, Hreinn, Steinberg, Stacy, Streit, Fabian, Strohmaier, Jana, Tansey, Katherine E., Teismann, Henning, Teumer, Alexander, Thompson, Wesley, Thomson, Pippa A., Thorgeirsson, Thorgeir E., Traylor, Matthew, Treutlein, Jens, Trubetskoy, Vassily, Uitterlinden, André G., Umbricht, Daniel, Van der Auwera, Sandra, van Hemert, Albert M., Viktorin, Alexander, Visscher, Peter M., Wang, Yunpeng, Webb, Bradley T., Weinsheimer, Shantel Marie, Wellmann, Jürgen, Willemsen, Gonneke, Witt, Stephanie H., Wu, Yang, Xi, Hualin S., Yang, Jian, Zhang, Futao, Arolt, Volker, Baune, Bernhard T., Berger, Klaus, Boomsma, Dorret I., Cichon, Sven, Dannlowski, Udo, de Geus, E. J. C., DePaulo, J. Raymond, Domenici, Enrico, Domschke, Katharina, Esko, Tõnu, Grabe, Hans J., Hamilton, Steven P., Hayward, Caroline, Heath, Andrew C., Kendler, Kenneth S., Kloiber, Stefan, Lewis, Glyn, Li, Qingqin S., Lucae, Susanne, Madden, Pamela A. F., Magnusson, Patrik K., Martin, Nicholas G., McIntosh, Andrew M., Metspalu, Andres, Mors, Ole, Mortensen, Preben Bo, Müller-Myhsok, Bertram, Nordentoft, Merete, Nöthen, Markus M., O’Donovan, Michael C., Paciga, Sara A., Pedersen, Nancy L., Penninx, Brenda W. J. H., Perlis, Roy H., Porteous, David J., Potash, James B., Preisig, Martin, Rietschel, Marcella, Schaefer, Catherine, Schulze, Thomas G., Smoller, Jordan W., Stefansson, Kari, Tiemeier, Henning, Uher, Rudolf, Völzke, Henry, Weissman, Myrna M., Werge, Thomas, Lewis, Cathryn M., Levinson, Douglas F., Breen, Gerome, Børglum, Anders D., Sullivan, Patrick F., Räikkönen, Katri, Binder, Elisabeth B., Consortium, Major Depressive Disorder Working Group of the Psychiatric Genomics
Publikováno v:
Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium 2019, ' Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns ', Nature Communications, vol. 10, no. 1, 2548 . https://doi.org/10.1038/s41467-019-10461-0
University of Queensland 2019, ' Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns ', Nature Communications, vol. 10, no. 1, 2548, pp. 1-18 . https://doi.org/10.1038/s41467-019-10461-0
Nature Communications, 10:2548. Nature Publishing Group
Nature Communications
Czamara, D, Eraslan, G K, Page, C M, Lahti, J, Lahti-Pulkkinen, M, Hämäläinen, E, Kajantie, E, Laivuori, H, Villa, P M, Reynolds, R M, Nystad, W, Håberg, S E, London, S J, O’Donnell, K J, Garg, E, Meaney, M J, Entringer, S, Wadhwa, P D, Buss, C, Jones, M J, Lin, D T S, MacIsaac, J L, Kobor, M S, Koen, N, Zar, H J, Koenen, K C, Dalvie, S, Stein, D J, Kondofersky, I, Müller, N S, Beekman, A T F, Jansen, R, Middeldorp, C M, Milaneschi, Y, Peyrot, W J, Schoevers, R, Smit, J H, de Geus, E J C, Penninx, B W J H, Posthuma, D, Smit, J H, Theis, F J, Räikkönen, K, Binder, E B & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium 2019, ' Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns ', Nature Communications, vol. 10, no. 1, 2548 . https://doi.org/10.1038/s41467-019-10461-0
Nature Communications, 10(1):2548. Nature Publishing Group
Digibug. Repositorio Institucional de la Universidad de Granada
instname
Nature Communications, 10(1):2548, 1-18. Nature Publishing Group
NATURE COMMUNICATIONS
Nature Communications, Vol 10, Iss 1, Pp 1-18 (2019)
Nature communications, 10(1):2548. Nature Publishing Group
Czamara, D, Eraslan, G, Page, C M, Lahti, J, Lahti-Pulkkinen, M, Hämäläinen, E, Kajantie, E, Laivuori, H, Villa, P M, Reynolds, R M, Nystad, W, Håberg, S E, London, S J, O'Donnell, K J, Garg, E, Meaney, M J, Entringer, S, Wadhwa, P D, Buss, C, Jones, M J, Lin, D T S, MacIsaac, J L, Kobor, M S, Koen, N, Zar, H J, Koenen, K C, Dalvie, S, Stein, D J, Kondofersky, I, Müller, N S, Theis, F J, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Räikkönen, K & Binder, E B 2019, ' Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns ', Nature Communications, vol. 10, 2548 . https://doi.org/10.1038/s41467-019-10461-0
Nature Communications 10(1), 2548 (2019). doi:10.1038/s41467-019-10461-0
Czamara, D, Abdellaoui, A, Beekman, A T F, Derks, E M, Dolan, C V, Hottenga, J J, Jansen, R, Mbarek, H, Middeldorp, C M, Milaneschi, Y, Nivard, M G, Posthuma, D, Boomsma, D I, Penninx, B W J H, Binder, E B & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium 2019, ' Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns ', Nature Communications, vol. 10, no. 1, 2548, pp. 1-18 . https://doi.org/10.1038/s41467-019-10461-0
Czamara, D, Eraslan, G, Page, C M, Lahti, J, Lahti-Pulkkinen, M, Hämäläinen, E, Kajantie, E, Laivuori, H, Villa, P M, Reynolds, R M, Nystad, W, Håberg, S E, London, S J, O’Donnell, K J, Garg, E, Meaney, M J, Entringer, S, Wadhwa, P D, Buss, C, Jones, M J, Lin, D T S, MacIsaac, J L, Kobor, M S, Koen, N, Zar, H J, Koenen, K C, Dalvie, S, Stein, D J, Kondofersky, I, Müller, N S, Theis, F J, Wray, N R, Ripke, S, Mattheisen, M, Trzaskowski, M, Byrne, E M, Abdellaoui, A, Adams, M J, Agerbo, E, Air, T M, Andlauer, T F M, Bacanu, S-A, Bækvad-Hansen, M, Beekman, A T F, Bigdeli, T B, Blackwood, D H R, Bryois, J, Buttenschøn, H N, Bybjerg-Grauholm, J, Cai, N, Castelao, E, Christensen, J H, Clarke, T-K, Coleman, J R I, Colodro-Conde, L, Couvy-Duchesne, B, Craddock, N, Crawford, G E, Davies, G, Deary, I J, Degenhardt, F, Derks, E M, Direk, N, Dolan, C V, Dunn, E C, Eley, T C, Escott-Price, V, Kiadeh, F F H, Finucane, H K, Forstner, A J, Frank, J, Gaspar, H A, Gill, M, Goes, F S, Gordon, S D, Grove, J, Hall, L S, Hansen, C S, Hansen, T F, Herms, S, Hickie, I B, Hoffmann, P, Homuth, G, Horn, C, Hottenga, J-J, Hougaard, D M, Ising, M, Jansen, R, Jorgenson, E, Knowles, J A, Kohane, I S, Kraft, J, Kretzschmar, W W, Krogh, J, Kutalik, Z, Li, Y, Lind, P A, MacIntyre, D J, MacKinnon, D F, Maier, R M, Maier, W, Marchini, J, Mbarek, H, McGrath, P, McGuffin, P, Medland, S E, Mehta, D, Middeldorp, C M, Mihailov, E, Milaneschi, Y, Milani, L, Mondimore, F M, Montgomery, G W, Mostafavi, S, Mullins, N, Nauck, M, Ng, B, Nivard, M G, Nyholt, D R, O’Reilly, P F, Oskarsson, H, Owen, M J, Painter, J N, Pedersen, C B, Pedersen, M G, Peterson, R E, Pettersson, E, Peyrot, W J, Pistis, G, Posthuma, D, Quiroz, J A, Qvist, P, Rice, J P, Riley, B P, Rivera, M, Mirza, S S, Schoevers, R, Schulte, E C, Shen, L, Shi, J, Shyn, S I, Sigurdsson, E, Sinnamon, G C B, Smit, J H, Smith, D J, Stefansson, H, Steinberg, S, Streit, F, Strohmaier, J, Tansey, K E, Teismann, H, Teumer, A, Thompson, W, Thomson, P A, Thorgeirsson, T E, Traylor, M, Treutlein, J, Trubetskoy, V, Uitterlinden, A G, Umbricht, D, Van der Auwera, S, van Hemert, A M, Viktorin, A, Visscher, P M, Wang, Y, Webb, B T, Weinsheimer, S M, Wellmann, J, Willemsen, G, Witt, S H, Wu, Y, Xi, H S, Yang, J, Zhang, F, Arolt, V, Baune, B T, Berger, K, Boomsma, D I, Cichon, S, Dannlowski, U, de Geus, E J C, DePaulo, J R, Domenici, E, Domschke, K, Esko, T, Grabe, H J, Hamilton, S P, Hayward, C, Heath, A C, Kendler, K S, Kloiber, S, Lewis, G, Li, Q S, Lucae, S, Madden, P A F, Magnusson, P K, Martin, N G, McIntosh, A M, Metspalu, A, Mors, O, Mortensen, P B, Müller-Myhsok, B, Nordentoft, M, Nöthen, M M, O’Donovan, M C, Paciga, S A, Pedersen, N L, Penninx, B W J H, Perlis, R H, Porteous, D J, Potash, J B, Preisig, M, Rietschel, M, Schaefer, C, Schulze, T G, Smoller, J W, Stefansson, K, Tiemeier, H, Uher, R, Völzke, H, Weissman, M M, Werge, T, Lewis, C M, Levinson, D F, Breen, G, Børglum, A D, Sullivan, P F, Räikkönen, K, Binder, E B & Consortium, M D D W G O T P G 2019, ' Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns ', Nature Communications, vol. 10, no. 1, 2548 . https://doi.org/10.1038/s41467-019-10461-0
Nature communications, vol 10, iss 1
Nature communications, vol. 10, no. 1, pp. 2548
University of Queensland 2019, ' Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns ', Nature Communications, vol. 10, no. 1, 2548, pp. 1-18 . https://doi.org/10.1038/s41467-019-10461-0
Nature Communications, 10:2548. Nature Publishing Group
Nature Communications
Czamara, D, Eraslan, G K, Page, C M, Lahti, J, Lahti-Pulkkinen, M, Hämäläinen, E, Kajantie, E, Laivuori, H, Villa, P M, Reynolds, R M, Nystad, W, Håberg, S E, London, S J, O’Donnell, K J, Garg, E, Meaney, M J, Entringer, S, Wadhwa, P D, Buss, C, Jones, M J, Lin, D T S, MacIsaac, J L, Kobor, M S, Koen, N, Zar, H J, Koenen, K C, Dalvie, S, Stein, D J, Kondofersky, I, Müller, N S, Beekman, A T F, Jansen, R, Middeldorp, C M, Milaneschi, Y, Peyrot, W J, Schoevers, R, Smit, J H, de Geus, E J C, Penninx, B W J H, Posthuma, D, Smit, J H, Theis, F J, Räikkönen, K, Binder, E B & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium 2019, ' Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns ', Nature Communications, vol. 10, no. 1, 2548 . https://doi.org/10.1038/s41467-019-10461-0
Nature Communications, 10(1):2548. Nature Publishing Group
Digibug. Repositorio Institucional de la Universidad de Granada
instname
Nature Communications, 10(1):2548, 1-18. Nature Publishing Group
NATURE COMMUNICATIONS
Nature Communications, Vol 10, Iss 1, Pp 1-18 (2019)
Nature communications, 10(1):2548. Nature Publishing Group
Czamara, D, Eraslan, G, Page, C M, Lahti, J, Lahti-Pulkkinen, M, Hämäläinen, E, Kajantie, E, Laivuori, H, Villa, P M, Reynolds, R M, Nystad, W, Håberg, S E, London, S J, O'Donnell, K J, Garg, E, Meaney, M J, Entringer, S, Wadhwa, P D, Buss, C, Jones, M J, Lin, D T S, MacIsaac, J L, Kobor, M S, Koen, N, Zar, H J, Koenen, K C, Dalvie, S, Stein, D J, Kondofersky, I, Müller, N S, Theis, F J, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Räikkönen, K & Binder, E B 2019, ' Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns ', Nature Communications, vol. 10, 2548 . https://doi.org/10.1038/s41467-019-10461-0
Nature Communications 10(1), 2548 (2019). doi:10.1038/s41467-019-10461-0
Czamara, D, Abdellaoui, A, Beekman, A T F, Derks, E M, Dolan, C V, Hottenga, J J, Jansen, R, Mbarek, H, Middeldorp, C M, Milaneschi, Y, Nivard, M G, Posthuma, D, Boomsma, D I, Penninx, B W J H, Binder, E B & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium 2019, ' Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns ', Nature Communications, vol. 10, no. 1, 2548, pp. 1-18 . https://doi.org/10.1038/s41467-019-10461-0
Czamara, D, Eraslan, G, Page, C M, Lahti, J, Lahti-Pulkkinen, M, Hämäläinen, E, Kajantie, E, Laivuori, H, Villa, P M, Reynolds, R M, Nystad, W, Håberg, S E, London, S J, O’Donnell, K J, Garg, E, Meaney, M J, Entringer, S, Wadhwa, P D, Buss, C, Jones, M J, Lin, D T S, MacIsaac, J L, Kobor, M S, Koen, N, Zar, H J, Koenen, K C, Dalvie, S, Stein, D J, Kondofersky, I, Müller, N S, Theis, F J, Wray, N R, Ripke, S, Mattheisen, M, Trzaskowski, M, Byrne, E M, Abdellaoui, A, Adams, M J, Agerbo, E, Air, T M, Andlauer, T F M, Bacanu, S-A, Bækvad-Hansen, M, Beekman, A T F, Bigdeli, T B, Blackwood, D H R, Bryois, J, Buttenschøn, H N, Bybjerg-Grauholm, J, Cai, N, Castelao, E, Christensen, J H, Clarke, T-K, Coleman, J R I, Colodro-Conde, L, Couvy-Duchesne, B, Craddock, N, Crawford, G E, Davies, G, Deary, I J, Degenhardt, F, Derks, E M, Direk, N, Dolan, C V, Dunn, E C, Eley, T C, Escott-Price, V, Kiadeh, F F H, Finucane, H K, Forstner, A J, Frank, J, Gaspar, H A, Gill, M, Goes, F S, Gordon, S D, Grove, J, Hall, L S, Hansen, C S, Hansen, T F, Herms, S, Hickie, I B, Hoffmann, P, Homuth, G, Horn, C, Hottenga, J-J, Hougaard, D M, Ising, M, Jansen, R, Jorgenson, E, Knowles, J A, Kohane, I S, Kraft, J, Kretzschmar, W W, Krogh, J, Kutalik, Z, Li, Y, Lind, P A, MacIntyre, D J, MacKinnon, D F, Maier, R M, Maier, W, Marchini, J, Mbarek, H, McGrath, P, McGuffin, P, Medland, S E, Mehta, D, Middeldorp, C M, Mihailov, E, Milaneschi, Y, Milani, L, Mondimore, F M, Montgomery, G W, Mostafavi, S, Mullins, N, Nauck, M, Ng, B, Nivard, M G, Nyholt, D R, O’Reilly, P F, Oskarsson, H, Owen, M J, Painter, J N, Pedersen, C B, Pedersen, M G, Peterson, R E, Pettersson, E, Peyrot, W J, Pistis, G, Posthuma, D, Quiroz, J A, Qvist, P, Rice, J P, Riley, B P, Rivera, M, Mirza, S S, Schoevers, R, Schulte, E C, Shen, L, Shi, J, Shyn, S I, Sigurdsson, E, Sinnamon, G C B, Smit, J H, Smith, D J, Stefansson, H, Steinberg, S, Streit, F, Strohmaier, J, Tansey, K E, Teismann, H, Teumer, A, Thompson, W, Thomson, P A, Thorgeirsson, T E, Traylor, M, Treutlein, J, Trubetskoy, V, Uitterlinden, A G, Umbricht, D, Van der Auwera, S, van Hemert, A M, Viktorin, A, Visscher, P M, Wang, Y, Webb, B T, Weinsheimer, S M, Wellmann, J, Willemsen, G, Witt, S H, Wu, Y, Xi, H S, Yang, J, Zhang, F, Arolt, V, Baune, B T, Berger, K, Boomsma, D I, Cichon, S, Dannlowski, U, de Geus, E J C, DePaulo, J R, Domenici, E, Domschke, K, Esko, T, Grabe, H J, Hamilton, S P, Hayward, C, Heath, A C, Kendler, K S, Kloiber, S, Lewis, G, Li, Q S, Lucae, S, Madden, P A F, Magnusson, P K, Martin, N G, McIntosh, A M, Metspalu, A, Mors, O, Mortensen, P B, Müller-Myhsok, B, Nordentoft, M, Nöthen, M M, O’Donovan, M C, Paciga, S A, Pedersen, N L, Penninx, B W J H, Perlis, R H, Porteous, D J, Potash, J B, Preisig, M, Rietschel, M, Schaefer, C, Schulze, T G, Smoller, J W, Stefansson, K, Tiemeier, H, Uher, R, Völzke, H, Weissman, M M, Werge, T, Lewis, C M, Levinson, D F, Breen, G, Børglum, A D, Sullivan, P F, Räikkönen, K, Binder, E B & Consortium, M D D W G O T P G 2019, ' Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns ', Nature Communications, vol. 10, no. 1, 2548 . https://doi.org/10.1038/s41467-019-10461-0
Nature communications, vol 10, iss 1
Nature communications, vol. 10, no. 1, pp. 2548
Publisher's version (útgefin grein)
Epigenetic processes, including DNA methylation (DNAm), are among the mechanisms allowing integration of genetic and environmental factors to shape cellular function. While many studies have investigated eith
Epigenetic processes, including DNA methylation (DNAm), are among the mechanisms allowing integration of genetic and environmental factors to shape cellular function. While many studies have investigated eith
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c80ec638009e6c5234c8c642a27e23b
https://curis.ku.dk/portal/da/publications/integrated-analysis-of-environmental-and-genetic-influences-on-cord-blood-dna-methylation-in-newborns(b69e43ee-1a66-4e67-8d6e-1a5007f88d83).html
https://curis.ku.dk/portal/da/publications/integrated-analysis-of-environmental-and-genetic-influences-on-cord-blood-dna-methylation-in-newborns(b69e43ee-1a66-4e67-8d6e-1a5007f88d83).html
Autor:
Peter P. Zandi, Lisa Jones, Aartjan T.F. Beekman, Christine Fraser, Andreas J. Forstner, Nese Direk, Mark Lathrop, Jesper Krogh, Merete Nordentoft, Bradley T. Webb, Yihan Li, Michael Bauer, Qingqin S. Li, Daniel J. Smith, Carsten Horn, Robert C. Thompson, René Breuer, Eli A. Stahl, David A. Collier, Richard Williamson, Boomsma, Dorret, I, Céline S. Reinbold, Laura J. Scott, Manolis Kogevinas, Jacob Lawrence, Caroline Hayward, Nicholas J. Schork, Penelope A. Lind, Wade H. Berrettini, John B. Vincent, Toni-Kim Clarke, Henry Voelzke, Stacy Steinberg, Hreinn Stefansson, Dean F. MacKinnon, Thorgeir E. Thorgeirsson, Niamh Mullins, Esben Agerbo, Rudolf Uher, Christina M. Hultman, Pamela A. F. Madden, Eva C. Schulte, Matthew Flickinger, Sebastian Zöllner, Kenneth S. Kendler, Urban Ösby, Enrique Castelao, Michael John Owen, Colm O'Dushlaine, Jens Treutlein, Joanna Hauser, Markus M. Noethen, Erin N. Smith, James McKay, Sandra Van der Auwera, Erin C. Dunn, Steven P. Hamilton, Martin Schalling, Helmut Vedder, Katherine Gordon-Smith, Fabio Rivas, Matthias Nauck, James B. Potash, Morten Mattingsdal, Ling Shen, Tim B. Bigdeli, Kimberly Chambert, Volker Arolt, Daniel L. Koller, Annelie Nordin Adolfsson, Na Cai, Nicholas G. Martin, Carlos N. Pato, Georg Homuth, Jonas Bybjerg-Grauholm, Alexander Teumer, Wesley K. Thompson, Hamel Patel, Jian Yang, Margit Burmeister, Frank Bellivier, Jodie N. Painter, Enda M. Byrne, Margarita Rivera, Nicholas John Craddock, Tatiana Foroud, Shaun Purcell, Paul D. Shilling, David Craig, Vanessa Kiyomi Ota, Michael Boehnke, Devin Absher, Stéphane Jamain, Anne Farmer, Yunpeng Wang, Ole Mors, William A. Scheftner, Jack D. Barchas, Robert Maier, Stanley J. Watson, Allan H. Young, Baptiste Couvy-Duchesne, Jakob Grove, Rick Jansen, John P. Rice, Gerome Breen, Eske M. Derks, Ingrid Melle, Tiffany A. Greenwood, Manuel Mattheisen, Bernard Ng, Edward M. Scolnick, Stefan Kloiber, Lili Milani, Yuri Milaneschi, Fermín Mayoral, Engilbert Sigurdsson, Sarah E. Medland, Wolfgang Maier, Alan F. Schatzberg, Myrna M. Weissman, Jun Li, John R. Kelsoe, Eric Jorgenson, Grant C.B. Sinnamon, Preben Bo Mortensen, Jana Strohmaier, William Byerley, Michel G. Nivard, Richard M. Myers, Evelin Mihailov, Gustavo Turecki, Benjamin S. Pickard, Ian J. Deary, Bernhard T. Baune, Marian L. Hamshere, Stephanie H. Witt, Patrick F. Sullivan, Jennifer L. Moran, Farnush Farhadi Hassan Kiadeh, Cathryn M. Lewis, Srdjan Djurovic, Ian B. Hickie, Hans J. Grabe, Helena Gaspar, Francis J. McMahon, Catherine Schaefer, Guy A. Rouleau, Sandra Meier, Derek W. Morris, Tõnu Esko, Wouter J. Peyrot, Markus Schwarz, Silviu-Alin Bacanu, Adam Wright, Melvin G. McInnis, Elaine K. Green, Douglas M. Ruderfer, Danielle Posthuma, Franziska Degenhardt, Per Qvist, Henriette N. Buttenschøn, Jolanta Lissowska, Stephan Ripke, Nicholas Bass, Giorgio Pistis, Emma M. Quinn, Shantel Weinsheimer, Howard J. Edenberg, Sintia Iole Belangero, Charles Curtis, Ashley R. Winslow, Tracy M. Air, Johannes H. Smit, Isaac S. Kohane, Wei Xu, Pamela B. Mahon, Neonila Szeszenia-Dabrowska, Gonneke Willemsen, Ivan Nikolov, Sven Cichon, Gregory E. Crawford, David M. Hougaard, E.J.C. de Geus, Klaus Berger, Evaristus A. Nwulia, Fernando S. Goes, Pablo Cervantes, Udo Dannlowski, Rolf Adolfsson, Thomas G. Schulze, Bruno Etain, Mark J. Adams, Thomas Hansen, Hugh Gurling, Fan Guo Meng, Judith A. Badner, Julien Bryois, Mateus Jose Abdalla Diniz, Rodrigo A. Bressan, Radhika Kandaswamy, Josef Frank, I. Nicol Ferrier, Bertram Mueller-Myhsok, Manuel A. R. Ferreira, Marion Leboyer, Futao Zhang, Valentina Moskvina, Patrik K. E. Magnusson, Laura M. Huckins, Douglas Blackwood, Michael Gill, Jianxin Shi, Dale R. Nyholt, Nancy L. Pedersen, André G. Uitterlinden, Henning Tiemeier, Vassily Trubetskoy, Scott D. Gordon, Ian Jones, Grant W. Montgomery, Martin Preisig, Cristiana Cruceanu, Sara A. Paciga, Lena Backlund, Abdel Abdellaoui, Andres Metspalu, Gunnar Morken, Marcus Ising, Sascha B. Fischer, Lilijana Oruc, Sian Caesar, Sarah Kittel-Schneider, Thalia C. Eley, Vihra Milanova, Thomas Werge, Andrew Heath, Katherine E. Tansey, Thomas W. Muehleisen, Jane H. Christensen, Chunyu Liu, Mikael Landén, Douglas F. Levinson, Julia Kraft, Juergen Wellmann, Coleman, Jonathan R., I, Peng Zhang, Glyn Lewis, Henning Teismann, Hamdi Mbarek, Carsten Bøcker Pedersen, Szabolcs Szelinger, Alexander Viktorin, Paul Brennan, Brenda W.J.H. Penninx, Maciej Trzaskowski, Yang Wu, Katharina Domschke, John Strauss, Hilary K. Finucane, Detelina Grozeva, Peter Holmans, Saira Saeed Mirza, Ole A. Andreassen, John I. Nurnberger, Lynsey S Hall, Till F. M. Andlauer, Sara Mostafavi, Andreas Reif, Joanna M. Biernacka, Christine Søholm Hansen, Hualin S. Xi, Stephen Newhouse, William E. Bunney, Andrew M. McIntosh, Anna Maaser, Enrico Domenici, Shyn, Stanley, I, Gail Davies, Warren W. Kretzschmar, Simone de Jong, Lucía Colodro-Conde, Pippa A. Thomson, Francis M. Mondimore, Martin Hautzinger, Cinnamon S. Bloss, Fabian Streit, James L. Kennedy, Erik Pettersson, Peter M. Visscher, Valentina Escott-Price, Donald J. MacIntyre, Johannes Schumacher, Kevin A. McGhee, Divya Mehta, Naomi R. Wray, Robert A. Schoevers, John A. Rice, Jordan W. Smoller, Anders D. Børglum, Susanne Lucae, Jorge A. Quiroz, Daniel Umbricht, Jouke-Jan Hottenga, Kari Stefansson, Marcella Rietschel, Zoltán Kutalik, Sarah E. Bergen, Paul F. O'Reilly, Amanda Dobbyn, Michael Conlon O'Donovan, Falk W. Lohoff, Caroline M. Nievergelt, David J. Porteous, Matthew Traylor, Brien P. Riley, Roy H. Perlis, J. Raymond DePaulo, Martin Alda, James A. Knowles, Cristiano Noto, Keith Matthews, Mark A. Frye, Patrick J. McGrath, Roseann E. Peterson, David St Clair, Roel A. Ophoff, William Coryell, Peter McGuffin, Andiara Calado Saloma Rodrigues, Elliot S. Gershon, Conor V. Dolan, Janice M. Fullerton, Weihua Guan, Niklas Långström, Pamela Sklar, Paul Lichtenstein, Per Hoffmann, Ary Gadelha, Alan W. McLean, Andrew McQuillin, Philip B. Mitchell, Huda Akil, Piotr M. Czerski, Michael Steffens, Hogni Oskarsson, Soumya Raychaudhuri, Marcos L. Santoro, Elisabeth B. Binder, Christel M. Middeldorp, Jose G. Para, Jurgen Del-Favero, Vishwajit L. Nimgaonkar, Peter R. Schofield, Stefan Herms, Marie Bækvad-Hansen, Andrea Pfennig, Albert M. van Hemert, Jutta Kammerer-Ciernioch, Adebayo Anjorin, Sara Paciga, William Lawson, George Kirov, Aiden Corvin, Maria Grigoroiu-Serbanescu, Marianne Giørtz Pedersen, Jonathan Marchini, Markus Leber, Maria Hipolito, Louise Frisén, Margitta Borrmann-Hassenbach, Amanda Elkin
Publikováno v:
Communications Biology
Communications biology 1(1), 163 (2018). doi:10.1038/s42003-018-0155-y
Communications Biology, Vol 1, Iss 1, Pp 1-10 (2018)
Communications biology, vol 1, iss 1
bioRxiv
de Jong, S, Diniz, M J A, Saloma, A, Gadelha, A, Santoro, M L, Ota, V K, Noto, C, Abdellaoui, A, Beekman, A T F, Dolan, C V, Hottenga, J J, Jansen, R, Mbarek, H, Milaneschi, Y, Nivard, M G, Posthuma, D, Boomsma, D I, de Geus, E J C, Curtis, C, Newhouse, S J, Patel, H, Hall, L S, O`Reilly, P F, Belangero, S I, Bressan, R A, Breen, G & Major Depressive Disorder and Bipolar Disorder Working Groups of the Psychiatric Genomics Consortium 2018, ' Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder ', Communications biology, vol. 1, 163, pp. 1-10 . https://doi.org/10.1038/s42003-018-0155-y
de Jong, S, Diniz, M J A, Saloma, A, Gadelha, A, Santoro, M L, Ota, V K, Noto, C, Curtis, C, Newhouse, S J, Patel, H, Hall, L S, O Reilly, P F, Belangero, S I, Bressan, R A, Breen, G & Major Depressive Disorder and Bipolar Disorder Working Groups of the Psychiatric Genomics Consortium (Per Qvist and Preben Bo Mortensen, members of-) 2018, ' Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder ', Communications Biology, vol. 1, 163 . https://doi.org/10.1038/s42003-018-0155-y
Communications biology, vol. 1, pp. 163
Communications biology, 1:163. Nature Publishing Group
COMMUNICATIONS BIOLOGY
Communications biology, 1:163, 1-10. Nature Research
2018, ' Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder ', Communications biology, vol. 1, pp. 163 . https://doi.org/10.1038/s42003-018-0155-y
Communications Biology, 1(1):163. Springer Nature
Communications biology 1(1), 163 (2018). doi:10.1038/s42003-018-0155-y
Communications Biology, Vol 1, Iss 1, Pp 1-10 (2018)
Communications biology, vol 1, iss 1
bioRxiv
de Jong, S, Diniz, M J A, Saloma, A, Gadelha, A, Santoro, M L, Ota, V K, Noto, C, Abdellaoui, A, Beekman, A T F, Dolan, C V, Hottenga, J J, Jansen, R, Mbarek, H, Milaneschi, Y, Nivard, M G, Posthuma, D, Boomsma, D I, de Geus, E J C, Curtis, C, Newhouse, S J, Patel, H, Hall, L S, O`Reilly, P F, Belangero, S I, Bressan, R A, Breen, G & Major Depressive Disorder and Bipolar Disorder Working Groups of the Psychiatric Genomics Consortium 2018, ' Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder ', Communications biology, vol. 1, 163, pp. 1-10 . https://doi.org/10.1038/s42003-018-0155-y
de Jong, S, Diniz, M J A, Saloma, A, Gadelha, A, Santoro, M L, Ota, V K, Noto, C, Curtis, C, Newhouse, S J, Patel, H, Hall, L S, O Reilly, P F, Belangero, S I, Bressan, R A, Breen, G & Major Depressive Disorder and Bipolar Disorder Working Groups of the Psychiatric Genomics Consortium (Per Qvist and Preben Bo Mortensen, members of-) 2018, ' Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder ', Communications Biology, vol. 1, 163 . https://doi.org/10.1038/s42003-018-0155-y
Communications biology, vol. 1, pp. 163
Communications biology, 1:163. Nature Publishing Group
COMMUNICATIONS BIOLOGY
Communications biology, 1:163, 1-10. Nature Research
2018, ' Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder ', Communications biology, vol. 1, pp. 163 . https://doi.org/10.1038/s42003-018-0155-y
Communications Biology, 1(1):163. Springer Nature
Psychiatric disorders are thought to have a complex genetic pathology consisting of interplay of common and rare variation. Traditionally, pedigrees are used to shed light on the latter only, while here we discuss the application of polygenic risk sc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf8e31d0d65994c29da2992d71dc1c70
https://hdl.handle.net/1956/19697
https://hdl.handle.net/1956/19697