Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Yuma Yamada"'
Publikováno v:
Journal of Controlled Release
Due to the rapid changes that have occurred in the field of drug discovery and the recent developments in the early 21st century, the role of drug delivery systems (DDS) has become increasingly more important. For the past 20 years, our laboratory ha
Autor:
Mitsue Hibino, Yusuke Sato, Yuma Yamada, Manabu Tokeshi, Masatoshi Maeki, Naoki Fujishita, Hideyoshi Harashima
Publikováno v:
Journal of Pharmaceutical Sciences. 108:2668-2676
A number of drugs that are currently on the market, as well as new candidates for drugs, are poorly water soluble. Because of this, a need exists to develop drug formulations that will permit the expanded use of such drugs. The use of liposomes and l
Publikováno v:
Journal of Controlled Release
The era of Nanomedicine has arrived with the approval of ONPATTRO™ by the FDA in 2018. Lipid nanoparticle (LNP) technology has succeeded in delivering siRNA to the human liver in genetic diseases and has also been applied to mRNA vaccinations for C
Autor:
Yuma Yamada, Hideyoshi Harashima
Publikováno v:
Methods in Molecular Biology ISBN: 9781071612613
Genetic mutations and defects in mitochondrial DNA (mtDNA) are associated with certain types of mitochondrial dysfunctions, ultimately resulting in the emergence of a variety of human diseases. To achieve an effective mitochondrial gene therapy, it w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f7e2799d331adce6f7ae035524fc443
https://doi.org/10.1007/978-1-0716-1262-0_14
https://doi.org/10.1007/978-1-0716-1262-0_14
Autor:
Yuma Yamada, Susumu Aoki, Shinji Hara, Naomichi Degawa, Minori Goto, Takekazu Yamane, Hikaru Nomura, Yoshishige Suzuki, Atsushi Shimura, Junichiro Urabe, Tsuyoshi Suzuki
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-7 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-7 (2021)
Bolometers are rectification devices that convert electromagnetic waves into direct current voltage through a temperature change. A superconducting bolometer has a responsivity of approximately 106–107 V/W under cryogenic temperatures at infrared w
Publikováno v:
Advanced drug delivery reviews.
Mitochondria carry out various essential functions including ATP production, the regulation of apoptosis and possess their own genome (mtDNA). Delivering target molecules to this organelle, it would make it possible to control the functions of cells
Autor:
Vasudevanpillai Biju, Satrialdi, Reina Munechika, Yuta Takano, Hideyoshi Harashima, Yuma Yamada
Publikováno v:
Chemical communications (Cambridge, England). 56(7)
The uncontrolled production of reactive oxygen species during photodynamic therapy (PDT) induces oxidative stress. The full potential of PDT is accomplished by delivery of a pi-extended porphyrin-type photosensitizer into mitochondria of tumor cells
Publikováno v:
Biomolecules
Biomolecules, Vol 10, Iss 1, p 83 (2020)
Biomolecules, Vol 10, Iss 1, p 83 (2020)
There have been many reports on the relationship between mitochondrial oxidative stress and various types of diseases. This review covers mitochondrial targeting photodynamic therapy and photothermal therapy as a therapeutic strategy for inducing mit
Autor:
Tsuyoshi Suzuki, Yoshishige Suzuki, Minori Goto, Shinji Miwa, Atsushi Shimura, Naomichi Degawa, Tomohito Mizuno, Susumu Aoki, Yuma Yamada, Junichiro Urabe, Takekazu Yamane, Shinji Hara
Publikováno v:
Applied Physics Letters. 118:192402
Quasi-maser operations using magnetic tunnel junctions (MTJs) that amplified the transmission of radio frequency (RF) signals through themselves are demonstrated. We measured the transmittance of heat-driven MTJs using a vector network analyzer and o
Publikováno v:
Biological & Pharmaceutical Bulletin. 40:2183-2190
While Coenzyme Q10 (CoQ10) is thought to be effective for the treatment of a variety of diseases, it limits its cellular uptake. Because of the hydrophobic nature of CoQ10, it is reasonable to assume that it could be encapsulated within a liposomal c