Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Chen Liang"'
Publikováno v:
Biomedical Chromatography. 34
Xianglian pill, a TCM prescription, consists of Rhizome Coptidis and Radix Aucklandiae, and has been used to treat gastrointestinal disease for many years. Berberine, jatrorrhizin, coptisine and palmatine are four representative alkaloids in Xianglia
Autor:
Yucheng Wang, Ling Ma, Chen Liang, Huiyu Zhou, Biao Dong, Juxian Wang, Zhen Wang, Yujia Wang, Mei Zhu, Guoning Zhang, Shan Cen, Jinming Zhou
Publikováno v:
European journal of medicinal chemistry. 185
Introducing pyrimidine bases, the basic components of nucleic acid, to P2 ligands might enhance the potency of Human Immunodeficiency Virus-1 (HIV-1) protease inhibitors because of the carbonyl and amino groups promoting the formation of extensive hy
Autor:
Shu Hui Chen, Shun Fen Tzeng, Quynh-Trang Do, Hsin Chen, Huei-Chen Liang, Chih-Yen Wang, Ming-Chun Ku, Yi-Chen Liu
Publikováno v:
Journal of proteome research. 17(8)
Catechol estrogens (CEs) are metabolic electrophiles that actively undergo covalent interaction with cellular proteins, influencing molecular function. There is no feasible method to identify their binders in a living system. Herein, we developed a c
Autor:
Chiao Chen Chen, Tzu-Fan Wang, Chih Hsing Wu, Huei Chen Liang, Shu Hui Chen, Chieh Ming Fang, Juei Tang Cheng, Ming Chun Ku, Jung-Hsiang Tai
Publikováno v:
Scientific Reports
Proteins, covalently modified by catechol estrogens (CEs), were identified recently from the blood serum of diabetic patients and referred to as estrogenized proteins. Estrogenization of circulating insulin may occur and affect its molecular function
Publikováno v:
PLoS Computational Biology, Vol 7, Iss 7, p e1002114 (2011)
PLoS Computational Biology
PLoS Computational Biology
The flexibility in the structure of calmodulin (CaM) allows its binding to over 300 target proteins in the cell. To investigate the structure-function relationship of CaM, we combined methods of computer simulation and experiments based on circular d