Zobrazeno 1 - 10
of 81
pro vyhledávání: '"le Borgne"'
Autor:
Birus, Robin, El-Awaad, Ehab, Ballentin, Laurens, Alchab, Faten, Aichele, Dagmar, Ettouati, Laurent, Götz, Claudia, Le Borgne, Marc, Jose, Joachim
Publikováno v:
FEBS Open Bio
FEBS Open Bio, 2022, 12, pp.394-411. ⟨10.1002/2211-5463.13346⟩
FEBS Open Bio, Wiley Open Access/Elsevier, 2021, ⟨10.1002/2211-5463.13346⟩
FEBS Open Bio, Vol 12, Iss 2, Pp 394-411 (2022)
FEBS Open Bio, 2022, 12, pp.394-411. ⟨10.1002/2211-5463.13346⟩
FEBS Open Bio, Wiley Open Access/Elsevier, 2021, ⟨10.1002/2211-5463.13346⟩
FEBS Open Bio, Vol 12, Iss 2, Pp 394-411 (2022)
Highly pleiotropic and constitutively active protein kinase CK2 is a key target in cancer therapy, but only one small-molecule inhibitor has reached clinical trials—CX-4945. In this study, we present the indeno[1,2-b]indole derivative 5-isopropyl-4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa5fc80887648f7dbe36bac662669c89
https://repositorium.uni-muenster.de/transfer/miami/e07de578-a357-4ad5-a2a9-5e6e1e7da84e
https://repositorium.uni-muenster.de/transfer/miami/e07de578-a357-4ad5-a2a9-5e6e1e7da84e
Autor:
Ferhat Djerboua, Zineb Elbahri, Milad Baitiche, Dounia Sid, Zouhair Bouaziz, Mokhtar Boutahala, Marc Le Borgne
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry
Journal of Enzyme Inhibition and Medicinal Chemistry, 2021, 36 (1), pp.605-617. ⟨10.1080/14756366.2020.1869225⟩
Journal of Enzyme Inhibition and Medicinal Chemistry, Informa Healthcare, 2021, 36 (1), pp.605-617. ⟨10.1080/14756366.2020.1869225⟩
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 605-617 (2021)
Journal of Enzyme Inhibition and Medicinal Chemistry, 2021, 36 (1), pp.605-617. ⟨10.1080/14756366.2020.1869225⟩
Journal of Enzyme Inhibition and Medicinal Chemistry, Informa Healthcare, 2021, 36 (1), pp.605-617. ⟨10.1080/14756366.2020.1869225⟩
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 605-617 (2021)
International audience; The aim of this study was to prepare and characterise inclusion complexes of a low water-soluble drug, mefenamic acid (MA), with b-cyclodextrin (b-CD). First, the phase solubility diagram of MA in b-CD was drawn from 0 to 21
Autor:
Hemmani, Nada, Kerachni, Soumeya, Bayart, Caroline, Paladino, Joseph, Mularoni, Angélique, Le Borgne, Marc
Publikováno v:
3ème soirée recherche ISPB
3ème soirée recherche ISPB, Apr 2022, Lyon, France
3ème soirée recherche ISPB, Apr 2022, Lyon, France
International audience
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::e54596a53bddea8bdbb28c500ab1719b
https://hal.archives-ouvertes.fr/hal-03662109
https://hal.archives-ouvertes.fr/hal-03662109
Autor:
Rajendra Prasad, Attilio Di Pietro, Shweta Nim, Stéphane Moreau, Elisabeth Thivet, Luisa Ronga, Marc Le Borgne, Solène Savrimoutou, Mathieu Marchivie, Jean Guillon
Publikováno v:
RSC Advances
RSC Advances, Royal Society of Chemistry, 2020, 10 (5), pp.2915-2931. ⟨10.1039/C9RA09348F⟩
RSC Advances, 2020, 10 (5), pp.2915-2931. ⟨10.1039/C9RA09348F⟩
RSC Advances, Royal Society of Chemistry, 2020, 10 (5), pp.2915-2931. ⟨10.1039/C9RA09348F⟩
RSC Advances, 2020, 10 (5), pp.2915-2931. ⟨10.1039/C9RA09348F⟩
International audience; Two series of piperazinyl-pyrrolo[1,2-a]quinoxaline derivatives were prepared via a Buchwald–Hartwig cross-coupling reaction and then evaluated for their ability to inhibit the drug efflux activity of CaCdr1p and CaMdr1p tra
Autor:
Marc Le Borgne, Malika Berredjem, Mohamed Aissaoui, Zouhair Bouaziz, Sofiane Bouacida, Abdeslem Bouzina, Billel Belhani, Christelle Marminon
Publikováno v:
Research on Chemical Intermediates
Research on Chemical Intermediates, Springer Verlag, 2021, ⟨10.1007/s11164-020-04378-3⟩
Research on Chemical Intermediates, Springer Verlag, 2021, ⟨10.1007/s11164-020-04378-3⟩
We demonstrate here a rapid and comfortable synthetic sequence to benzothiadiazinone dioxide (six-membered cyclic sulfamide) derivatives, analogues of Monastrol, which is known to be a specific mitotic kinesin Eg5 inhibitor. Fourteen novel compounds
Autor:
Caroline Bayart, Angélique Mularoni, Nada Hemmani, Soumeya Kerachni, Joachim Jose, Patrice Gouet, Joseph Paladino, Marc Le Borgne
Publikováno v:
Pharmaceuticals
Pharmaceuticals, 2022, 15 (6), pp.756. ⟨10.3390/ph15060756⟩
Pharmaceuticals, 2022, 15 (6), pp.756. ⟨10.3390/ph15060756⟩
International audience; Tetanus toxoid (TTd) plays an important role in the pharmaceutical world, especially in vaccines. The toxoid is obtained after formaldehyde treatment of the tetanus toxin. In parallel, current emphasis in the drug discovery fi
Autor:
Arnaud Chaix, Audrey Griveau, Thomas Defforge, Virginie Grimal, Brice Le Borgne, Gaël Gautier, Joël Eyer
Publikováno v:
RSC Advances
RSC Advances, 2022, 12 (19), pp.11708-11714. ⟨10.1039/D2RA00508E⟩
RSC Advances, 2022, 12 (19), pp.11708-11714. ⟨10.1039/D2RA00508E⟩
International audience; Glioblastoma multiforme (GBM) is the most malignant primary brain tumor of the central nervous system. Despite advances in therapy, it remains largely untreatable, in part due to the low permeability of chemotherapeutic drugs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c34b364ae07aed435100ea08d801cb7
https://hal-univ-tours.archives-ouvertes.fr/hal-03664758/file/d2ra00508e.pdf
https://hal-univ-tours.archives-ouvertes.fr/hal-03664758/file/d2ra00508e.pdf
Autor:
Saïd Yous, Pal Rongved, Samar Issa, Marc Le Borgne, Nicolas Bedel, Zouhair Bouaziz, Anthony Prandina
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry
Journal of Enzyme Inhibition and Medicinal Chemistry, 2019, 34 (1), pp.1321-1346. ⟨10.1080/14756366.2019.1640692⟩
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 1321-1346 (2019)
Journal of Enzyme Inhibition and Medicinal Chemistry, Informa Healthcare, 2019, 34 (1), pp.1321-1346. ⟨10.1080/14756366.2019.1640692⟩
Journal of Enzyme Inhibition and Medicinal Chemistry, 2019, 34 (1), pp.1321-1346. ⟨10.1080/14756366.2019.1640692⟩
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 1321-1346 (2019)
Journal of Enzyme Inhibition and Medicinal Chemistry, Informa Healthcare, 2019, 34 (1), pp.1321-1346. ⟨10.1080/14756366.2019.1640692⟩
International audience; For over half a century, the carbazole skeleton has been the key structural motif of many biologically active compounds including natural and synthetic products. Carbazoles have taken an important part in all the existing anti
Autor:
Diogo Henrique Kita, Vivian Rotuno Moure, Malika Berredjem, Geraldo Picheth, Sabrina Lusvarghi, Ingrid Fatima Zattoni, Nathalie Guragossian, Fabiane Gomes de Moraes Rego, Suresh V. Ambudkar, Christelle Marminon, Marc Le Borgne, Glaucio Valdameri, Marcos Brown Gonçalves, Zouhair Bouaziz, Joachim Jose, Sofiane Bouacida, Billel Belhani, Thomas Moulenat
Publikováno v:
Scientific Reports
Scientific Reports, 2021, 11 (1), pp.1788. ⟨10.1038/s41598-020-79892-w⟩
Scientific Reports, Nature Publishing Group, 2021, 11 (1), pp.1788. ⟨10.1038/s41598-020-79892-w⟩
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Scientific Reports, 2021, 11 (1), pp.1788. ⟨10.1038/s41598-020-79892-w⟩
Scientific Reports, Nature Publishing Group, 2021, 11 (1), pp.1788. ⟨10.1038/s41598-020-79892-w⟩
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
The ATP-binding cassette transporter ABCG2 mediates the efflux of several chemotherapeutic drugs, contributing to the development of multidrug resistance (MDR) in many cancers. The most promising strategy to overcome ABCG2-mediated MDR is the use of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3c8cc9ea76f4d3466fc3592b560030c
https://hal.science/hal-03126318
https://hal.science/hal-03126318
Autor:
Marc Le Borgne, J. Jose, D. Lindenblatt, B. Witulski, Maria Bretner, Karsten Niefind, Anna Nickelsen, Jennifer Hochscherf, Zouhair Bouaziz, V.M. Applegate, Christelle Marminon-Davoust
Publikováno v:
6th International Electronic Conference on Medicinal Chemistry
6th International Electronic Conference on Medicinal Chemistry, Nov 2020, Basel, Switzerland. pp.7505, ⟨10.3390/ECMC2020-07505⟩
6th International Electronic Conference on Medicinal Chemistry, Nov 2020, Basel, Switzerland. pp.7505, ⟨10.3390/ECMC2020-07505⟩
International audience