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pro vyhledávání: '"Padhukasahasram, Badri"'
Autor:
Padhukasahasram, Badri, Halperin, Eran, Wessel, Jennifer, Thomas, Daryl, Silver, Elana, Trumbower, Heather, Cargill, Michele, Stephan, Dietrich
Publikováno v:
2010 PLoS ONE 5(12): e14338. doi:10.1371/journal.pone.0014338
The prevalence of common chronic non-communicable diseases (CNCDs) far overshadows the prevalence of both monogenic and infectious diseases combined. All CNCDs, also called complex genetic diseases, have a heritable genetic component that can be used
Externí odkaz:
http://arxiv.org/abs/1006.4642
Autor:
Padhukasahasram, Badri
Publikováno v:
Methodology and Computing in Applied Probability, Online First, 11 May 2012
I describe an analytical approximation for calculating the short-term probability of loss of a chromosome under the neutral Wright-Fisher model with recombination. I also present an upper and lower bound for this probability. Exact analytical calcula
Externí odkaz:
http://arxiv.org/abs/1006.0519
Autor:
Padhukasahasram, Badri
The accuracy of the recombination estimation method of Padhukasahasram et al. 2006 can be improved by including additional informative summary statistics in the rejection scheme and by simulating datasets under a fixed segregating sites model. A C++
Externí odkaz:
http://arxiv.org/abs/1005.5533