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Male-mediated developmental toxicity has been of concern for many years. The public became aware of male-mediated developmental toxicity in the early 1990s when it was reported that men working at Sellafield might be causing leukemia in their childre
Externí odkaz:
http://hdl.handle.net/10454/10416
Autor:
Xue, J., He, M., Niu, Y., Liu, H., Crawford, A., Coates, Philip D., Chen, D., Shi, R., Zhang, L.
Infection is the major reason of GTR/GBR membrane failure in clinical application. In this work, we developed GTR/GBR nanofiber membranes with localized drug delivery function to prevent infection. Metronidazole (MNA), an antibiotic, was successfully
Externí odkaz:
http://hdl.handle.net/10454/10813
Autor:
Lem, Kristina Yvonne
This study estimates the association between dietary factors and spontaneous pancreatitis in dogs. A case-control study was conducted using 198 dogs with a clinical diagnosis of pancreatitis and 187 control dogs with a diagnosis of renal failure with
Externí odkaz:
http://hdl.handle.net/1969.1/ETD-TAMU-1504
AIMS/HYPOTHESIS: We previously demonstrated that animals fed a high-fat (HF) diet for 10 weeks developed insulin resistance and behavioural inflexibility. We hypothesised that intervention with metformin would diminish the HF-feeding-evoked cognitive
Externí odkaz:
http://hdl.handle.net/10454/6095
Autor:
Corrêa, Sonia A.L., Hunter, C.J., Palygin, O., Wauters, S.C., Martin, K.J., McKenzie, C., McKelvey, K., Morris, R.G., Pankratov, Y., Arthur, J.S., Frenguelli, B.G.
The ability of neurons to modulate synaptic strength underpins synaptic plasticity, learning and memory, and adaptation to sensory experience. Despite the importance of synaptic adaptation in directing, reinforcing, and revising the behavioral respon
Externí odkaz:
http://hdl.handle.net/10454/5942
Autor:
Lamont, F.R., Tomlinson, D.C., Cooper, Patricia A., Shnyder, Steven, Chester, J.D., Knowles, M.A.
BACKGROUND: Activating mutations of FGFR3 are frequently identified in superficial urothelial carcinoma (UC) and increased expression of FGFR1 and FGFR3 are common in both superficial and invasive UC. METHODS: The effects of inhibition of receptor ac
Externí odkaz:
http://hdl.handle.net/10454/6061
The molecular identity of ion channels which confer PCO(2)/pH sensitivity in the brain is unclear. Heteromeric Kir4.1/Kir5.1 channels are highly sensitive to inhibition by intracellular pH and are widely expressed in several brainstem nuclei involved
Externí odkaz:
http://hdl.handle.net/10454/5950
Autor:
Burns, C.J., Fantino, E., Powell, A.K., Shnyder, Steven, Cooper, Patricia A., Nelson, S., Christophi, C., Malcontenti-Wilson, C., Dubljevic, V., Harte, M.F., Joffe, M., Phillips, I.D., Segal, D., Wilks, A.F., Smith, G.D.
The orally active microtubule-disrupting agent (S)-1-ethyl-3-(2-methoxy-4-(5-methyl-4-((1-(pyridin-3-yl)butyl)amino)pyrimidin-2- yl)phenyl)urea (CYT997), reported previously by us (Bioorg Med Chem Lett 19:4639-4642, 2009; Mol Cancer Ther 8:3036-3045,
Externí odkaz:
http://hdl.handle.net/10454/5902
Autor:
Sharov, A.A., Mardaryev, Andrei N., Sharova, T.Y., Grachtchouk, M., Atoyan, R., Byers, H.R., Seykora, J.T., Overbeek, P., Dlugosz, A., Botchkarev, Vladimir A.
Bone morphogenetic proteins (BMPs) play pivotal roles in the regulation of skin development. To study the role of BMPs in skin tumorigenesis, BMP antagonist noggin was used to generate keratin 14-targeted transgenic mice. In contrast to wild-type mic
Externí odkaz:
http://hdl.handle.net/10454/6185
Autor:
Lem, Kristina Yvonne
This study estimates the association between dietary factors and spontaneous pancreatitis in dogs. A case-control study was conducted using 198 dogs with a clinical diagnosis of pancreatitis and 187 control dogs with a diagnosis of renal failure with
Externí odkaz:
http://hdl.handle.net/1969.1/ETD-TAMU-1504