Zobrazeno 1 - 6
of 6
pro vyhledávání: ''
Male-mediated developmental toxicity has been of concern for many years. The public became aware of male-mediated developmental toxicity in the early 1990s when it was reported that men working at Sellafield might be causing leukemia in their childre
Externí odkaz:
http://hdl.handle.net/10454/10416
Autor:
Lamont, F.R., Tomlinson, D.C., Cooper, Patricia A., Shnyder, Steven, Chester, J.D., Knowles, M.A.
BACKGROUND: Activating mutations of FGFR3 are frequently identified in superficial urothelial carcinoma (UC) and increased expression of FGFR1 and FGFR3 are common in both superficial and invasive UC. METHODS: The effects of inhibition of receptor ac
Externí odkaz:
http://hdl.handle.net/10454/6061
Autor:
Burns, C.J., Fantino, E., Powell, A.K., Shnyder, Steven, Cooper, Patricia A., Nelson, S., Christophi, C., Malcontenti-Wilson, C., Dubljevic, V., Harte, M.F., Joffe, M., Phillips, I.D., Segal, D., Wilks, A.F., Smith, G.D.
The orally active microtubule-disrupting agent (S)-1-ethyl-3-(2-methoxy-4-(5-methyl-4-((1-(pyridin-3-yl)butyl)amino)pyrimidin-2- yl)phenyl)urea (CYT997), reported previously by us (Bioorg Med Chem Lett 19:4639-4642, 2009; Mol Cancer Ther 8:3036-3045,
Externí odkaz:
http://hdl.handle.net/10454/5902
Autor:
Sharov, A.A., Mardaryev, Andrei N., Sharova, T.Y., Grachtchouk, M., Atoyan, R., Byers, H.R., Seykora, J.T., Overbeek, P., Dlugosz, A., Botchkarev, Vladimir A.
Bone morphogenetic proteins (BMPs) play pivotal roles in the regulation of skin development. To study the role of BMPs in skin tumorigenesis, BMP antagonist noggin was used to generate keratin 14-targeted transgenic mice. In contrast to wild-type mic
Externí odkaz:
http://hdl.handle.net/10454/6185
Publikováno v:
ETSU Faculty Works.
Recent evidence suggests that oxidatively modified forms of low-density lipoprotein (LDL) may be particularly atherogenic. In this investigation, the catabolism of human LDL modified by lipid peroxidation in vitro was studied with a recirculating rat
Externí odkaz:
https://dc.etsu.edu/etsu-works-2/284
Publikováno v:
ETSU Faculty Works.
Myeloid-derived suppressor cells (MDSCs) prolong sepsis by promoting immunosuppression. We reported that sepsis MDSC development requires long non-coding RNA Hotairm1 interactions with S100A9. Using a mouse model that simulates the immunobiology of s
Externí odkaz:
https://dc.etsu.edu/etsu-works-2/210