Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Yannick Goumon"'
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
IntroductionPain mostly arises because specialized cells called nociceptors detect harmful or potentially harmful stimuli. In lower animals with less convoluted nervous system, these responses are believed to be purely nociceptive. Amongst invertebra
Externí odkaz:
https://doaj.org/article/35be4f17c62d401b9c525cbdee6143be
Autor:
Francis Schneider, Pierrick Le Borgne, Jean-Etienne Herbrecht, François Danion, Morgane Solis, Sophie Hellé, Cosette Betscha, Raphaël Clere-Jehl, François Lefebvre, Vincent Castelain, Yannick Goumon, Marie-Hélène Metz-Boutigue
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
IntroductionNeuroendocrine cells release Catestatin (CST) from Chromogranin A (CgA) to regulate stress responses. As regards COVID-19 patients (COVID+) requiring oxygen supply, to date nobody has studied CST as a potential mediator in the regulation
Externí odkaz:
https://doaj.org/article/4e519e549b614e9cb6c1438552678dc0
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Morphine remains the gold standard painkiller available to date to relieve severe pain. Morphine metabolism leads to the production of two predominant metabolites, morphine-3-glucuronide (M3G) and morphine-6-glucuronide (M6G). This metabolism involve
Externí odkaz:
https://doaj.org/article/7a459bce21d74449b0d2db31388c47d7
Autor:
Albin A. Bernardin, Sarah Colombani, Antoine Rousselot, Virginie Andry, Yannick Goumon, Hélène Delanoë-Ayari, Côme Pasqualin, Bernard Brugg, Etienne D. Jacotot, Jean-Luc Pasquié, Alain Lacampagne, Albano C. Meli
Publikováno v:
Cells, Vol 11, Iss 23, p 3764 (2022)
In the heart, cardiac function is regulated by the autonomic nervous system (ANS) that extends through the myocardium and establishes junctions at the sinus node and ventricular levels. Thus, an increase or decrease in neuronal activity acutely affec
Externí odkaz:
https://doaj.org/article/2e0a14cbc3b34ccf857da9d87e2c7340
Autor:
Florian Gabel, Anne-Sophie Aubry, Volodya Hovhannisyan, Virginie Chavant, Ivan Weinsanto, Tando Maduna, Pascal Darbon, Yannick Goumon
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Background: Tamoxifen is used to treat breast cancer and cancer recurrences. After administration, tamoxifen is converted into two more potent antitumor compounds, 4OH-tamoxifen and endoxifen by the CYP3A4/5 and 2D6 enzymes in human. These active com
Externí odkaz:
https://doaj.org/article/92fd90d05a924de9a5fef797b2d64d8f
Autor:
Ivan Weinsanto, Jinane Mouheiche, Alexis Laux-Biehlmann, François Delalande, Arnaud Marquette, Virginie Chavant, Florian Gabel, Sarah Cianferani, Alexandre Charlet, Marie-Odile Parat, Yannick Goumon
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Externí odkaz:
https://doaj.org/article/cf4e64c61c9840dba7d14cd2aa8be692
Autor:
Ivan Weinsanto, Jinane Mouheiche, Alexis Laux-Biehlmann, François Delalande, Arnaud Marquette, Virginie Chavant, Florian Gabel, Sarah Cianferani, Alexandre Charlet, Marie-Odile Parat, Yannick Goumon
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
Morphine is an analgesic alkaloid used to relieve severe pain, and irreversible binding of morphine to specific unknown proteins has been previously observed. In the brain, changes in the expression of energy metabolism enzymes contribute to behavior
Externí odkaz:
https://doaj.org/article/bc95e2d0e67545c99ea409795946c48d
Publikováno v:
Frontiers in Pharmacology, Vol 7 (2016)
Macrophages are abundant in the tumor microenvironment where they adopt a pro-tumor phenotype following alternative polarization induced by paracrine factors from cancer and stromal cells. In contrast, classically activated macrophages have tumoricid
Externí odkaz:
https://doaj.org/article/fc42edca14e4408b9190fcc21fcf9685
Autor:
Elise Glattard, Ingeborg D Welters, Thomas Lavaux, Arnaud H Muller, Alexis Laux, Dan Zhang, Alexander R Schmidt, François Delalande, Benoît-Joseph Laventie, Sylvie Dirrig-Grosch, Didier A Colin, Alain Van Dorsselaer, Dominique Aunis, Marie-Hélène Metz-Boutigue, Francis Schneider, Yannick Goumon
Publikováno v:
PLoS ONE, Vol 5, Iss 1, p e8791 (2010)
BACKGROUND: Mammalian cells synthesize morphine and the respective biosynthetic pathway has been elucidated. Human neutrophils release this alkaloid into the media after exposure to morphine precursors. However, the exact role of endogenous morphine
Externí odkaz:
https://doaj.org/article/607fd6a32562424790e6afdcfe3a6533
Autor:
Arnaud Muller, Elise Glattard, Omar Taleb, Véronique Kemmel, Alexis Laux, Monique Miehe, François Delalande, Guy Roussel, Alain Van Dorsselaer, Marie-Hélène Metz-Boutigue, Dominique Aunis, Yannick Goumon
Publikováno v:
PLoS ONE, Vol 3, Iss 2, p e1641 (2008)
Morphine, the principal active agent in opium, is not restricted to plants, but is also present in different animal tissues and cell types, including the mammalian brain. In fact, its biosynthetic pathway has been elucidated in a human neural cell li
Externí odkaz:
https://doaj.org/article/60998688eb2448449cf8b6b4960f3c1c