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pro vyhledávání: '"Pablo Helguera"'
Autor:
Sunyoung Hwang, Jessica F. Williams, Maja Kneissig, Maria Lioudyno, Isabel Rivera, Pablo Helguera, Jorge Busciglio, Zuzana Storchova, Megan C. King, Eduardo M. Torres
Publikováno v:
Cell Reports, Vol 29, Iss 8, Pp 2473-2488.e5 (2019)
Summary: An abnormal number of chromosomes, or aneuploidy, accounts for most spontaneous abortions, causes developmental defects, and is associated with aging and cancer. The molecular mechanisms by which aneuploidy disrupts cellular function remain
Externí odkaz:
https://doaj.org/article/78c6c24f9d924edbbe6dfedfbd9f773e
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e14200 (2010)
Down's syndrome (DS) is the most common genetic cause of mental retardation. Reduced number and aberrant architecture of dendritic spines are common features of DS neuropathology. However, the mechanisms involved in DS spine alterations are not known
Externí odkaz:
https://doaj.org/article/8edcf01576ea481d92c9e3b6026ecf08