Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Nguyen Thuy Thuong Thuong"'
Autor:
Liane S. Canas, Trinh H. K. Dong, Daniel Beasley, Joseph Donovan, Jon O. Cleary, Richard Brown, Nguyen Thuy Thuong Thuong, Phu Hoan Nguyen, Ha Thi Nguyen, Reza Razavi, Sebastien Ourselin, Guy E. Thwaites, Marc Modat, the Vietnam ICU Translational Applications Laboratory (VITAL) Investigators
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Tuberculous meningitis (TBM) is the most lethal form of tuberculosis. Clinical features, such as coma, can predict death, but they are insufficient for the accurate prognosis of other outcomes, especially when impacted by co-morbidities such
Externí odkaz:
https://doaj.org/article/08a080fc43a44141b75690f09cfec498
Autor:
Trinh Huu Khanh Dong, Joseph Donovan, Nghiem My Ngoc, Do Dang Anh Thu, Ho Dang Trung Nghia, Pham Kieu Nguyet Oanh, Nguyen Hoan Phu, Vu Thi Ty Hang, Nguyen Van Vinh Chau, Nguyen Thuy Thuong Thuong, Le Van Tan, Guy E. Thwaites, Ronald B. Geskus
Publikováno v:
BMC Infectious Diseases, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Diagnosis of tuberculous meningitis (TBM) is hampered by the lack of a gold standard. Current microbiological tests lack sensitivity and clinical diagnostic approaches are subjective. We therefore built a diagnostic model that can
Externí odkaz:
https://doaj.org/article/37362129d3004cc6911f5d8f62d8354d
Autor:
Matthew Silcocks, Xuling Chang, Nguyen Thuy Thuong Thuong, Youwen Qin, Dang Thi Minh Ha, Phan Vuong Khac Thai, Srinivasan Vijay, Do Dang Anh Thu, Vu Thi Ngoc Ha, Hoang Ngoc Nhung, Nguyen Huu Lan, Nguyen Thi Quynh Nhu, David Edwards, Artika Nath, Kym Pham, Nguyen Duc Bang, Tran Thi Hong Chau, Guy Thwaites, A. Dorothee Heemskerk, Chiea Chuen Khor, Yik Ying Teo, Michael Inouye, Rick Twee-Hee Ong, Maxine Caws, Kathryn E. Holt, Sarah J. Dunstan
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 6 (2023)
ABSTRACT A previous investigation has elucidated the landscape of Mtb genomic diversity and transmission dynamics in Ho Chi Minh City, Vietnam. Here, we expand the scope of this survey by adding a substantial number of additional genomes (total sampl
Externí odkaz:
https://doaj.org/article/789ee16a126b4aecb13e3374ea2e93ed
Autor:
Tracy R. Richardson, Bronwyn Smith, Stephanus T. Malherbe, Jane Alexandra Shaw, Firdows Noor, Candice MacDonald, Gian D. van der Spuy, Kim Stanley, Alida Carstens, Tarryn-Lee Fisher, Ilana van Rensburg, Marika Flinn, Candice Snyders, Isaac Johnson, Bernadine Fransman, Hazel Dockrell, Guy Thwaites, Nguyen Thuy Thuong Thuong, Claudia Schacht, Harriet Mayanja-Kizza, Mary Nsereko, Elisa M. Tjon Kon Fat, Paul L.A.M. Corstjens, Annemieke Geluk, Morton Ruhwald, Adam Penn-Nicholson, Novel N. Chegou, Jayne Sutherland, Gerhard Walzl, TrENDx consortium
Publikováno v:
BMC Infectious Diseases, Vol 23, Iss 1, Pp 1-9 (2023)
Abstract Background To improve tuberculosis (TB) diagnosis, the World Health Organisation (WHO) has called for a non-sputum based triage test to focus TB testing on people with a high likelihood of having active pulmonary tuberculosis (TB). Various h
Externí odkaz:
https://doaj.org/article/f668d770ba9a4961ba4011426a3ad46e
Autor:
Edwin Ardiansyah, Julian Avila-Pacheco, Le Thanh Hoang Nhat, Sofiati Dian, Dao Nguyen Vinh, Hoang Thanh Hai, Kevin Bullock, Bachti Alisjahbana, Mihai G Netea, Riwanti Estiasari, Trinh Thi Bich Tram, Joseph Donovan, Dorothee Heemskerk, Tran Thi Hong Chau, Nguyen Duc Bang, Ahmad Rizal Ganiem, Rovina Ruslami, Valerie ACM Koeken, Raph L Hamers, Darma Imran, Kartika Maharani, Vinod Kumar, Clary B Clish, Reinout van Crevel, Guy Thwaites, Arjan van Laarhoven, Nguyen Thuy Thuong Thuong
Publikováno v:
eLife, Vol 12 (2023)
Background: Cellular metabolism is critical for the host immune function against pathogens, and metabolomic analysis may help understand the characteristic immunopathology of tuberculosis. We performed targeted metabolomic analyses in a large cohort
Externí odkaz:
https://doaj.org/article/2cf2690812f847abb9ee5aa2f2ed4a1d
Autor:
Duc Hong Du, Ronald B Geskus, Yanlin Zhao, Luigi Ruffo Codecasa, Daniela Maria Cirillo, Reinout van Crevel, Dyshelly Nurkartika Pascapurnama, Lidya Chaidir, Stefan Niemann, Roland Diel, Shaheed Vally Omar, Louis Grandjean, Sakib Rokadiya, Arturo Torres Ortitz, Nguyễn Hữu Lân, Đặng Thị Minh Hà, E Grace Smith, Esther Robinson, Martin Dedicoat, Le Thanh Hoang Nhat, Guy E Thwaites, Le Hong Van, Nguyen Thuy Thuong Thuong, Timothy M Walker
Publikováno v:
PLOS Global Public Health, Vol 3, Iss 12, p e0001788 (2023)
Six lineages of Mycobacterium tuberculosis sensu stricto (which excludes M. africanum) are described. Single-country or small observational data suggest differences in clinical phenotype between lineages. We present strain lineage and clinical phenot
Externí odkaz:
https://doaj.org/article/3e1033c2e23f45f384d8e5166dd225e4
Autor:
Le Hong Van, Phan Trieu Phu, Dao Nguyen Vinh, Vo Thanh Son, Nguyen Thi Hanh, Le Thanh Hoang Nhat, Nguyen Huu Lan, Truong Van Vinh, Nguyen Thi Mai Trang, Dang Thi Minh Ha, Guy E. Thwaites, Nguyen Thuy Thuong Thuong
Publikováno v:
BMC Infectious Diseases, Vol 20, Iss 1, Pp 1-10 (2020)
Abstract Background Multidrug resistant tuberculosis (MDR-TB) remains a serious public health problem with poor treatment outcomes. Predictors of poor outcomes vary in different regions. Vietnam is among the top 30 high burden of MDR-TB countries. We
Externí odkaz:
https://doaj.org/article/b4aae187361e41d181782848c43ed683
Autor:
Nathan C Bahr, Fiona V Cresswell, Nguyen Thuy Thuong Thuong, Rachel P.J. Lai, Angharad G. Davis, David R Boulware, Robert J Wilkinson, Johan Schoeman, Marise Bremer, Joseph Donovan, Ronald Van Toorn, Guy E Thwaites, Ariba Dadabhoy
Publikováno v:
Wellcome Open Research, Vol 5 (2021)
A dysregulated host immune response significantly contributes to morbidity and mortality in tuberculous meningitis (TBM). Effective host directed therapies (HDTs) are critical to improve survival and clinical outcomes. Currently only one HDT, dexamet
Externí odkaz:
https://doaj.org/article/1082f9028b78463baff862754b13c9a1
Autor:
Dao Nguyen Vinh, Dang Thi Minh Ha, Nguyen Thi Hanh, Guy Thwaites, Maciej F. Boni, Hannah E. Clapham, Nguyen Thuy Thuong Thuong
Publikováno v:
BMC Infectious Diseases, Vol 18, Iss 1, Pp 1-13 (2018)
Abstract Background The depletion of CD4 cell is the underlying reason for TB hyper-susceptibility among people with HIV. Consequently, the trend of TB dynamics is usually hidden by the HIV outbreak. Methods Here, we aim to evaluate the trend of TB d
Externí odkaz:
https://doaj.org/article/0eb59bed0f3240e18856df371494f113
Autor:
Peter J Dodd, Muhammad Osman, Fiona V Cresswell, Anna M Stadelman, Nguyen Huu Lan, Nguyen Thuy Thuong Thuong, Morris Muzyamba, Lisa Glaser, Sicelo S Dlamini, James A Seddon
Publikováno v:
PLOS Global Public Health, Vol 1, Iss 12, p e0000069 (2021)
Tuberculous meningitis (TBM) is the most lethal form of tuberculosis. The incidence and mortality of TBM is unknown due to diagnostic challenges and limited disaggregated reporting of treated TBM by existing surveillance systems. We aimed to estimate
Externí odkaz:
https://doaj.org/article/5e2ac906120a4251bf9ed8535523dcee