Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Michael L. Gross"'
Autor:
Adi Levy, Michael L. Gross
Publikováno v:
Frontiers in Public Health, Vol 12 (2024)
Trigger warningThis article deals with combat experiences and their consequences and could be potentially disturbing.IntroductionMoral injury (MI) is a severe form of combat trauma that shatters soldiers’ moral bearings as the result of killing in
Externí odkaz:
https://doaj.org/article/22646adf1f4e4f62a3d28ac011ddfecc
Autor:
Jagat Adhikari, James Heffernan, Melissa Edeling, Estefania Fernandez, Prashant N. Jethva, Michael S. Diamond, Daved H. Fremont, Michael L. Gross
Publikováno v:
Biomolecules, Vol 14, Iss 3, p 374 (2024)
Japanese encephalitis virus (JEV) remains a global public health concern due to its epidemiological distribution and the existence of multiple strains. Neutralizing antibodies against this infection have shown efficacy in in vivo studies. Thus, eluci
Externí odkaz:
https://doaj.org/article/eb43680e76c24949abc9fd9bd793d91c
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 24, p 17342 (2023)
We describe an investigation using structural mass spectrometry (MS) of the impact of two antibodies, 15497 and 15498, binding the highly flexible SARS-CoV-2 Nsp1 protein. We determined the epitopes and paratopes involved in the antibody–protein in
Externí odkaz:
https://doaj.org/article/a40e13f0746449c1b281b597603baf3f
Autor:
Shweta Kailasan, Ravi Kant, Madeleine Noonan-Shueh, Tulasikumari Kanipakala, Grant Liao, Sergey Shulenin, Daisy W. Leung, Richard A. Alm, Rajan P. Adhikari, Gaya K. Amarasinghe, Michael L. Gross, M. Javad Aman
Publikováno v:
mAbs, Vol 14, Iss 1 (2022)
Staphylococcus aureus carries an exceptional repertoire of virulence factors that aid in immune evasion. Previous single-target approaches for S. aureus-specific vaccines and monoclonal antibodies (mAbs) have failed in clinical trials due to the mult
Externí odkaz:
https://doaj.org/article/536d0a35d34246f88a85754222c857ae
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
The intrinsic flexibility of membranes proteins still poses a challenge in determining their active structure. Here the authors describe the development of a method that combines chemical footprinting and mass spectrometry to assist in determining th
Externí odkaz:
https://doaj.org/article/79f9a105291b4eca88c2f9f488f9ee6d
Autor:
Jonathan Moreno, Michael L. Gross, Jack Becker, Blake Hereth, Neil D. Shortland, Nicholas G. Evans
Publikováno v:
Frontiers in Big Data, Vol 5 (2022)
The military applications of AI raise myriad ethical challenges. Critical among them is how AI integrates with human decision making to enhance cognitive performance on the battlefield. AI applications range from augmented reality devices to assist l
Externí odkaz:
https://doaj.org/article/97b132a8babd4b8aafdbb00f212cf7f5
Publikováno v:
European Journal of Psychotraumatology, Vol 13, Iss 1 (2022)
Background Does exposure to events that transgress accepted norms, such as killing innocent civilians, prompt the psychological and emotional consequences of moral injury among soldiers? Moral injury is associated with negative emotions such as guilt
Externí odkaz:
https://doaj.org/article/4e28917795c34bb6b0fb8033d1795ac6
Autor:
Michael P. Doyle, Joseph R. Genualdi, Adam L. Bailey, Nurgun Kose, Christopher Gainza, Jessica Rodriguez, Kristen M. Reeder, Christopher A. Nelson, Prashant N. Jethva, Rachel E. Sutton, Robin G. Bombardi, Michael L. Gross, Justin G. Julander, Daved H. Fremont, Michael S. Diamond, James E. Crowe
Publikováno v:
mBio, Vol 13, Iss 3 (2022)
ABSTRACT Yellow fever virus (YFV) causes sporadic outbreaks of infection in South America and sub-Saharan Africa. While live-attenuated yellow fever virus vaccines based on three substrains of 17D are considered some of the most effective vaccines in
Externí odkaz:
https://doaj.org/article/db0fc1ff96ac4795a13221056ff7f496
Publikováno v:
Membranes, Vol 13, Iss 5, p 457 (2023)
Understanding the higher-order structure of membrane proteins (MPs), which are vital for numerous biological processes, is crucial for comprehending their function. Although several biophysical approaches have been used to study the structure of MPs,
Externí odkaz:
https://doaj.org/article/23ec0d403eeb4f5e9c6e03379d040c5a
Autor:
Chao Wu, Abraham J. Qavi, Austin B. Moyle, Nicole D. Wagner, Asmaa Hachim, Niloufar Kavian, Aidan R. Cole, Joyce Sweeney-Gibbons, Henry W. Rohrs, J.S. Malik Peiris, Christopher F. Basler, Michael L. Gross, Sophie A. Valkenburg, Christopher W. Farnsworth, Gaya K. Amarasinghe, Daisy W. Leung
Publikováno v:
STAR Protocols, Vol 2, Iss 4, Pp 100906- (2021)
Summary: Nucleocapsid proteins are essential for SARS-CoV-2 life cycle. Here, we describe protocols to gather domain-specific insights about essential properties of nucleocapsids. These assays include dynamic light scattering to characterize oligomer
Externí odkaz:
https://doaj.org/article/e32263235f994b63906d2a8175965a34