Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Marco L. Davila"'
Autor:
Justin C. Boucher, Bishwas Shrestha, Paresh Vishwasrao, Mark Leick, Estelle V. Cervantes, Tayyebb Ghafoor, Kayla Reid, Kristen Spitler, Bin Yu, Brian C. Betts, Jose A. Guevara-Patino, Marcela V. Maus, Marco L. Davila
Publikováno v:
Molecular Therapy: Oncolytics, Vol 31, Iss , Pp 100751- (2023)
CD33 and CD123 are expressed on the surface of human acute myeloid leukemia blasts and other noncancerous tissues such as hematopoietic stem cells. On-target off-tumor toxicities may limit chimeric antigen receptor T cell therapies that target both C
Externí odkaz:
https://doaj.org/article/950a3b2659db497d9c16853df8bab008
Autor:
Semira Sheikh, Sepideh Mokhtari, Jeffrey A. Silverman, Kayla Reid, Rawan Faramand, Marco L. Davila, Norman Franke, Frederick L. Locke, Michael D. Jain, Daniel Wong, John G. Kuruvilla
Publikováno v:
eJHaem, Vol 3, Iss 1, Pp 223-227 (2022)
Externí odkaz:
https://doaj.org/article/13b8610a64c74b59a0dc98940dbbade2
Autor:
Kenneth Cornetta, Lisa Duffy, Steven A. Feldman, Crystal L. Mackall, Marco L. Davila, Kevin J. Curran, Richard P. Junghans, Jean Yuh Tang, James N. Kochenderfer, Roisin O’Cearbhaill, Gary Archer, Hans-Peter Kiem, Nirali N. Shah, Cindy Delbrook, Rosie Kaplan, Renier J. Brentjens, Isabelle Rivière, Michel Sadelain, Steven A. Rosenberg
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 10, Iss , Pp 371-378 (2018)
Replication-competent retrovirus (RCR) is a safety concern for individuals treated with retroviral gene therapy. RCR detection assays are used to detect RCR in manufactured vector, transduced cell products infused into research subjects, and in the r
Externí odkaz:
https://doaj.org/article/d41ec9a65e514c438579bc848efe4243
Autor:
Jennifer M. Logue, Elisa Zucchetti, Christina A. Bachmeier, Gabriel S. Krivenko, Victoria Larson, Daniel Ninh, Giovanni Grillo, Biwei Cao, Jongphil Kim, Julio C. Chavez, Aliyah Baluch, Farhad Khimani, Aleksandr Lazaryan, Taiga Nishihori, Hien D. Liu, Javier Pinilla-Ibarz, Bijal D. Shah, Rawan Faramand, Anna E. Coghill, Marco L. Davila, Bhagirathbhai R. Dholaria, Michael D. Jain, Frederick L. Locke
Publikováno v:
Haematologica, Vol 106, Iss 4 (2020)
CD19 CAR T-cell therapy with axicabtagene ciloleucel (axi-cel) for relapsed or refractory (R/R) large B cell lymphoma (LBCL) may lead to durable remissions, however, prolonged cytopenias and infections may occur. In this single center retrospective s
Externí odkaz:
https://doaj.org/article/9b49d260a7484ec48b00e7dc0cef6f14
Autor:
Scott Christley, Walter Scarborough, Eddie Salinas, William H. Rounds, Inimary T. Toby, John M. Fonner, Mikhail K. Levin, Min Kim, Stephen A. Mock, Christopher Jordan, Jared Ostmeyer, Adam Buntzman, Florian Rubelt, Marco L. Davila, Nancy L. Monson, Richard H. Scheuermann, Lindsay G. Cowell
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
BackgroundRecent technological advances in immune repertoire sequencing have created tremendous potential for advancing our understanding of adaptive immune response dynamics in various states of health and disease. Immune repertoire sequencing produ
Externí odkaz:
https://doaj.org/article/ccf807b5dbf248eeac1ed7188f9e63bd
Autor:
Dae Hyun Lee, Sanjay Chandrasekhar, Michael D. Jain, Rahul Mhaskar, Kayla Reid, Sae Bom Lee, Salvatore Corallo, Melanie J. Hidalgo-Vargas, Abhishek Kumar, Julio Chavez, Bijal Shah, Aleksandr Lazaryan, Farhad Khimani, Taiga Nishihori, Christina Bachmeier, Rawan Faramand, Michael G. Fradley, Daniel Jeong, Guilherme H. Oliveira, Frederick L. Locke, Marco L Davila, Mohammed Alomar
Publikováno v:
Cardio-Oncology, Vol 9, Iss 1, Pp 1-9 (2023)
Abstract Background Chimeric antigen receptor T- Cell (CAR-T) immunotherapy has been a breakthrough treatment for various hematological malignancies. However, cardiotoxicities such as new-onset heart failure, arrhythmia, acute coronary syndrome and c
Externí odkaz:
https://doaj.org/article/2b3320c84568447e825867b260a94475
Autor:
Gang Zhou, David H Munn, Zhi-Chun Ding, Marco L Davila, Hongyan Xu, Nada S Aboelella, Caitlin Brandle, Ogacheko Okoko, Md Yeashin Gazi, Gregory Gorman, Roni Bollag, Locke J Bryan, Gary A Piazza
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 7 (2022)
Background Adoptive cell therapy (ACT) using genetically modified T cells has evolved into a promising treatment option for patients with cancer. However, even for the best-studied and clinically validated CD19-targeted chimeric antigen receptor (CAR
Externí odkaz:
https://doaj.org/article/a814f619a9934bacafbe74860b95a4f2
Autor:
Frederick L Locke, Yannick Bulliard, Bin Yu, Marco L Davila, Emiliano Roselli, Justin C Boucher, Gongbo Li, Hiroshi Kotani, Kristen Spitler, Kayla Reid, Estelle V Cervantes, Nhan Tu, Sae Bom Lee
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 10 (2021)
Externí odkaz:
https://doaj.org/article/2adf8c00760248dcb99a7c2fbda76d78
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 1 (2021)
Background Chimeric antigen receptor (CAR) T-cell therapy is an emerging option for cancer treatment, but its efficacy is limited, especially in solid tumors. This is partly because the CAR T cells become dysfunctional and exhausted in the tumor micr
Externí odkaz:
https://doaj.org/article/46fdf68b933c4b81816f119845ff0132
Autor:
Frederick L Locke, Elizabeth J Shpall, Jorg Dietrich, Daniel W Lee, Matthew J Frigault, Terry J Fry, Sara Alexander, Jennifer N Brudno, Colleen Callahan, Marco L Davila, Claudia Diamonte, Julie C Fitzgerald, Jennifer L Holter-Chakrabarty, Krishna V Komanduri, Shannon L Maude, Philip L McCarthy, Elena Mead, David T Teachey, Cameron J Turtle, Tom Whitehead
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Immune effector cell (IEC) therapies offer durable and sustained remissions in significant numbers of patients with hematological cancers. While these unique immunotherapies have improved outcomes for pediatric and adult patients in a number of disea
Externí odkaz:
https://doaj.org/article/d61d44366994471cbc391339ac6fd898