Zobrazeno 1 - 6
of 6
pro vyhledávání: '"John L. Magnani"'
Publikováno v:
Blood Cancer Journal, Vol 13, Iss 1, Pp 1-4 (2023)
Externí odkaz:
https://doaj.org/article/3d33aa4280c444ba8044bba083223d23
Autor:
Valerie Barbier, Johanna Erbani, Corrine Fiveash, Julie M. Davies, Joshua Tay, Michael R. Tallack, Jessica Lowe, John L. Magnani, Diwakar R. Pattabiraman, Andrew C. Perkins, Jessica Lisle, John E. J. Rasko, Jean-Pierre Levesque, Ingrid G. Winkler
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
The cell adhesion molecule E-selectin regulates haematopoietic stem cell self-renewal in the bone marrow vascular niche. Here, the authors show E-selectin adhesion directly induces survival signaling in acute myeloid leukaemia and therapeutic inhibit
Externí odkaz:
https://doaj.org/article/7dde84bbf79f4a748ecf6d1fab0d7161
Autor:
Sumana Devata, Dana E. Angelini, Susan Blackburn, Angela Hawley, Daniel D. Myers, Jordan K. Schaefer, Martina Hemmer, John L. Magnani, Helen M. Thackray, Thomas W. Wakefield, Suman L. Sood
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 4, Iss 2, Pp 193-204 (2020)
Abstract Background There is an unmet need for antithrombotic treatments for venous thromboembolic disease that do not increase bleeding risk. Selectins are cell adhesion molecules that augment thrombosis by activating immune cells to initiate the co
Externí odkaz:
https://doaj.org/article/154592a33fc54abd95ad195a38766fb3
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Neutrophils are essential to protect the host against invading pathogens but can promote disease progression in sickle cell disease (SCD) by becoming adherent to inflamed microvascular networks in peripheral tissue throughout the body. During the inf
Externí odkaz:
https://doaj.org/article/da729016f4884c87b849c6f33ad0f150
Autor:
Beat Ernst, Thomas Peters, Reinhold Oehrlein, Keith E. Norman, John L. Magnani, Wolfgang Jahnke, Beatrice Wagner, Christian Müller, Sébastien Marti, Zorica Dragic, Hartmuth C. Kolb
Publikováno v:
CHIMIA, Vol 55, Iss 4 (2001)
Selectin-mediated recruitment of leukocytes plays a crucial role in a number of diseases and pathological situations, for example in inflammation, reperfusion injury, rheumatoid arthritis and respiratory diseases. Substantial research efforts are dir
Externí odkaz:
https://doaj.org/article/b68097d494ed4343928f824c77805fce
Autor:
Ted Wun, Lori Styles, Laura DeCastro, Marilyn J Telen, Frans Kuypers, Anthony Cheung, William Kramer, Henry Flanner, Seungshin Rhee, John L Magnani, Helen Thackray
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e101301 (2014)
Sickle cell anemia is an inherited disorder of hemoglobin that leads to a variety of acute and chronic complications. Abnormal cellular adhesion, mediated in part by selectins, has been implicated in the pathophysiology of the vaso-occlusion seen in
Externí odkaz:
https://doaj.org/article/0a53d64b898b47b49ffe712d853c9594