Zobrazeno 1 - 10
of 4 347
pro vyhledávání: '"Hingorani A"'
Autor:
Mohan Hingorani, Hannah Stubley
Publikováno v:
Exploration of Targeted Anti-tumor Therapy, Vol 5, Iss 4, Pp 921-930 (2024)
The prognosis of metastatic esophageal cancer (EC) remains poor with an average life expectancy of around 9–12 months with standard systemic chemotherapy. The concept of oligometastatic disease (OMD) in EC cancer is controversial with no universall
Externí odkaz:
https://doaj.org/article/9cff5f06fc0f47d0bb093678c61711a2
Comparing the effects of CETP in East Asian and European ancestries: a Mendelian randomization study
Autor:
Diana Dunca, Sandesh Chopade, María Gordillo-Marañón, Aroon D. Hingorani, Karoline Kuchenbaecker, Chris Finan, Amand F. Schmidt
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract CETP inhibitors are a class of lipid-lowering drugs in development for treatment of coronary heart disease (CHD). Genetic studies in East Asian ancestry have interpreted the lack of CETP signal with low-density lipoprotein cholesterol (LDL-C
Externí odkaz:
https://doaj.org/article/23e5af9de5984d279421ac7ebb2dc74e
Autor:
Andrés M. Arias-Lorza, James R. Costello, Sunil R. Hingorani, Daniel D. Von Hoff, Ronald L. Korn, Natarajan Raghunand
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Pre-clinical and clinical studies have shown that PEGPH20 depletes intratumoral hyaluronic acid (HA), which is linked to high interstitial fluid pressures and poor distribution of chemotherapies. 29 patients with metastatic advanced solid tu
Externí odkaz:
https://doaj.org/article/efc4f39a74d3420ca38b41a64d4c8737
Autor:
Constantin-Cristian Topriceanu, Mit Shah, Matthew Webber, Fiona Chan, Hunain Shiwani, Marcus Richards, Jonathan Schott, Nishi Chaturvedi, James C. Moon, Alun D. Hughes, Aroon D. Hingorani, Declan P. O’Regan, Gabriella Captur
Publikováno v:
BMC Cardiovascular Disorders, Vol 24, Iss 1, Pp 1-17 (2024)
Abstract Background Although APOE ε4 allele carriage confers a risk for coronary artery disease, its persistence in humans might be explained by certain survival advantages (antagonistic pleiotropy). Methods Combining data from ~ 37,000 persons from
Externí odkaz:
https://doaj.org/article/11cdd86813114bbcb62a5c1ef1c08698
Autor:
Seth Lieberman, Daniel A. Rivera, Ryan Morton, Amrit Hingorani, Teresa L. Southard, Lynn Johnson, Jennifer Reukauf, Ryan E. Radwanski, Mingrui Zhao, Nozomi Nishimura, Oliver Bracko, Theodore H. Schwartz, Chris B. Schaffer
Publikováno v:
Advanced Science, Vol 11, Iss 29, Pp n/a-n/a (2024)
Abstract In partial onset epilepsy, seizures arise focally in the brain and often propagate. Patients frequently become refractory to medical management, leaving neurosurgery, which can cause neurologic deficits, as a primary treatment. In the cortex
Externí odkaz:
https://doaj.org/article/d22684f893044b91ac604fc32f314fdc
Autor:
Gregory Y H Lip, Kenneth K C Man, Wallis C Y Lau, Ian C K Wong, Wai K Leung, Aroon D Hingorani, Pajaree Mongkhon, Jan D Chobanov, Zixuan Wang, Edil Dayib
Publikováno v:
Open Heart, Vol 11, Iss 2 (2024)
Aims Women with atrial fibrillation (AF) are under-represented in randomised controlled trials (RCTs) of direct oral anticoagulants (DOACs). This systematic review and meta-analysis of RCTs and observational studies examined sex-specific outcomes of
Externí odkaz:
https://doaj.org/article/c80def62b06a4424a387ca21bb6dabe0
Autor:
A. Floriaan Schmidt, Chris Finan, Sandesh Chopade, Stephan Ellmerich, Martin N. Rossor, Aroon D. Hingorani, Mark B. Pepys
Publikováno v:
Open Biology, Vol 14, Iss 7 (2024)
The mechanisms responsible for neuronal death causing cognitive loss in Alzheimer's disease (AD) and many other dementias are not known. Serum amyloid P component (SAP) is a constitutive plasma protein, which is cytotoxic for cerebral neurones and al
Externí odkaz:
https://doaj.org/article/7b7fa5020a354c8684a1fb1ebee1aca7
Publikováno v:
In Journal of Vascular Surgery: Venous and Lymphatic Disorders May 2024 12(3)
Publikováno v:
Clinical Phytoscience, Vol 10, Iss 1, Pp 1-13 (2024)
Abstract Background There are very few drugs available for healing wounds in the aged population, which is more prone to chronic cutaneous wounds that are particularly hard to heal and require a long healing process. This study which deals with age-r
Externí odkaz:
https://doaj.org/article/105279ed583941e49109b455f98adb47
Autor:
Yuk M. Law, Christine Hsu, Sangeeta R. Hingorani, Michael Richards, David M. McMullan, Howard Jefferies, Jonathan Himmelfarb, Ronit Katz
Publikováno v:
Journal of Cardiothoracic Surgery, Vol 19, Iss 1, Pp 1-9 (2024)
Abstract Background Children undergoing cardiac surgery are at risk for acute kidney injury (AKI) and cardiac dysfunction. Opportunity exists in protecting end organ function with remote ischemic preconditioning. We hypothesize this intervention less
Externí odkaz:
https://doaj.org/article/8c5600781c9f4f928eb8cf1f2d01da23