Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Heleen Van Acker"'
Autor:
Eline Teirlinck, Ranhua Xiong, Toon Brans, Katrien Forier, Juan Fraire, Heleen Van Acker, Nele Matthijs, Riet De Rycke, Stefaan C. De Smedt, Tom Coenye, Kevin Braeckmans
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Eradication of bacterial infections can be hindered by poor penetration of antibiotics through biofilms. Here, Teirlinck et al. show that laser-induced vapour nanobubbles formed around plasmonic nanoparticles can be used to locally disturb biofilm in
Externí odkaz:
https://doaj.org/article/38e137de19b54a1fbd1552f4fff64076
Autor:
Heleen Van Acker, Aurélie Crabbé, Dukas Jurėnas, Lisa Ostyn, Andrea Sass, Simon Daled, Maarten Dhaenens, Dieter Deforce, Eline Teirlinck, Herlinde De Keersmaecker, Kevin Braeckmans, Laurence Van Melderen, Tom Coenye
Publikováno v:
Biofilm, Vol 1, Iss , Pp - (2019)
Burkholderia cenocepacia infections are difficult to treat due to resistance, biofilm formation and persistence. B. cenocepacia strain J2315 has a large multi-replicon genome (8.06 Mb) and the function of a large fraction of (conserved) hypothetical
Externí odkaz:
https://doaj.org/article/1813f374099d49bba0e33d369f424955
Autor:
Aurélie Crabbé, Lisa Ostyn, Sorien Staelens, Charlotte Rigauts, Martijn Risseeuw, Maarten Dhaenens, Simon Daled, Heleen Van Acker, Dieter Deforce, Serge Van Calenbergh, Tom Coenye
Publikováno v:
PLoS Pathogens, Vol 15, Iss 4, p e1007697 (2019)
Antibiotic susceptibility of bacterial pathogens is typically evaluated using in vitro assays that do not consider the complex host microenvironment. This may help explaining a significant discrepancy between antibiotic efficacy in vitro and in vivo,
Externí odkaz:
https://doaj.org/article/2706a68c47b6435aaafd17978aab5542
Autor:
Yunhui Zhang, Andrea Sass, Heleen Van Acker, Jasper Wille, Bruno Verhasselt, Filip Van Nieuwerburgh, Volkhard Kaever, Aurélie Crabbé, Tom Coenye
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
As one of the major pathogens in wound infections, Pseudomonas aeruginosa produces several virulence factors and forms biofilms; these processes are under the regulation of various quorum sensing (QS) systems. Therefore, QS has been regarded as a pro
Externí odkaz:
https://doaj.org/article/513a864fd99d4cbda05dfac24c5c3101
Autor:
Lisa Slachmuylders, Heleen Van Acker, Gilles Brackman, Andrea Sass, Filip Van Nieuwerburgh, Tom Coenye
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0190533 (2018)
Reduced antimicrobial susceptibility due to resistance and tolerance has become a serious threat to human health. An approach to overcome this reduced susceptibility is the use of antibiotic adjuvants, also known as potentiators. These are compounds
Externí odkaz:
https://doaj.org/article/b108b88035994e41b1c9bc39a27d655c
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0159837 (2016)
It was recently proposed that bactericidal antibiotics, besides through specific drug-target interactions, kill bacteria by a common mechanism involving the production of reactive oxygen species (ROS). However, this mechanism involving the production
Externí odkaz:
https://doaj.org/article/dd79758dae98447aab07609ca7601b0b
Autor:
Heleen Van Acker, Andrea Sass, Silvia Bazzini, Karen De Roy, Claudia Udine, Thomas Messiaen, Giovanna Riccardi, Nico Boon, Hans J Nelis, Eshwar Mahenthiralingam, Tom Coenye
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58943 (2013)
The presence of persister cells has been proposed as a factor in biofilm resilience. In the present study we investigated whether persister cells are present in Burkholderia cepacia complex (Bcc) biofilms, what the molecular basis of antimicrobial to
Externí odkaz:
https://doaj.org/article/75a0f0af5a134ed496e64330d8a78629
Autor:
Claudia Udine, Gilles Brackman, Silvia Bazzini, Silvia Buroni, Heleen Van Acker, Maria Rosalia Pasca, Giovanna Riccardi, Tom Coenye
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e55112 (2013)
Many putative virulence factors of Burkholderia cenocepacia are controlled by various quorum sensing (QS) circuits. These QS systems either use N-acyl homoserine lactones (AHL) or cis-2-dodecenoic acid ("Burkholderia diffusible signal factor", BDSF)
Externí odkaz:
https://doaj.org/article/edfa214c34d443bd96521099eaad4c1c