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Autor:
Aditi Goyal, Sonal Sharma, Shariq Qayyum, Ram Krishna Sahu, Navneet Kaur, Ravi Mehrotra, Mohit Kumar, Suresh Hedau, Usha Rani Singh
Publikováno v:
Journal of Cancer Research and Therapeutics, Vol 15, Iss 5, Pp 1147-1154 (2019)
Objectives: The purpose of the study is to investigate p16 protein expression and promoter methylation of p16 gene and their association with molecular subtypes based on parameter such as estrogen receptor (ER), progesterone receptor (PR), and human
Autor:
Ying Liu, Hongwei Sun, Junjie Liu, Boqing Li, Pengzhou Gai, Zhenyu Zhang, Xiaofei Ji, Xiuzhi Zhou
Publikováno v:
Journal of Cancer Research and Therapeutics, Vol 15, Iss 2, Pp 426-436 (2019)
Aims and Methods: Retrospectively, this paper compared the differences of the Epstein–Barr virus (EBV)-encoded small RNAs (EBERs), protein expression and gene mutations of tumor suppressor gene p53 (TP53) in keratinized nasopharyngeal squamous cell
Publikováno v:
Journal of Cancer Research and Therapeutics, Vol 14, Iss 8, Pp 114-119 (2018)
Purpose: Papillary thyroid carcinoma (PTC) has a strong propensity to metastasize to regional lymph nodes which increases the risk of local-regional relapse and affects the course of the disease. Molecular pathogenesis of lymph node metastasis (LNM)
Autor:
Mohammad Reza Abbaszadegan, Noorieh Sharifi, Soodabeh Abbasi Sani, Mohammad Mahdi Forghanifard, Alireza Jian Bagherpoor, Mahnaz Hashemi Bidokhti
Publikováno v:
Journal of Cancer Research and Therapeutics, Vol 14, Iss 5, Pp 1059-1064 (2018)
Background: Esophageal squamous cell carcinoma (ESCC) is considered as the seventh most common cancer worldwide, and the second prevalent malignancy in the north of Iran. A subfamily group of tumor-specific antigens, commonly specified as cancer/test
Publikováno v:
Journal of Cancer Research and Therapeutics, Vol 14, Iss 12, Pp 1188-1192 (2018)
Objective: To investigate the correlation between the expression of programmed death 1 (PD-1) and PD ligand-1 (PD-L1) in hepatocellular carcinoma (HCC) and clinical parameters. Materials and Methods: The study comprised tumor sections from 45 HCC pat
Publikováno v:
Journal of Cancer Research and Therapeutics, Vol 13, Iss 5, Pp 833-836 (2017)
Objective: The aim of this study was to evaluate the secreted protein acidic and rich in cysteine (SPARC) expression in breast cancer tissue and its association with patients' clinical pathology characteristics and prognosis. Materials and Methods: E
Publikováno v:
Journal of Cancer Research and Therapeutics, Vol 13, Iss 4, Pp 676-682 (2017)
Background: It is important to find reliable molecular markers or biological targets that associate with ovarian cancer (OC) metastasis for diagnosis and treatment. In this study, researchers investigated the regulated chain of microRNA-30c (miR-30c)
Autor:
Vijayalakshmi S Kotrashetti, Kishore Bhat, Sindhu Nair, Jagadish Hosmani, Ramakant Nayak, Pradeep Somannavar
Publikováno v:
Journal of Cancer Research and Therapeutics, Vol 9, Iss 4, Pp 624-629 (2013)
Objectives: Toll like receptors play an important role in innate and adaptive immune responses. Heat shock proteins play a significant role in cell proliferation, differentiation and oncogenesis. HSP70 acts as one of the ligands of TLR4 and binds to