Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Anna Mae Diehl"'
Autor:
William A. Murphy, Anna Mae Diehl, Matthew Shane Loop, Dong Fu, Cynthia D. Guy, Manal F. Abdelmalek, Georgia Sofia Karachaliou, Noora Sjöstedt, Sibylle Neuhoff, Paavo Honkakoski, Kim L. R. Brouwer
Publikováno v:
Hepatology Communications, Vol 8, Iss 3 (2024)
Background:. NAFLD is highly prevalent with limited treatment options. Bile acids (BAs) increase in the systemic circulation and liver during NAFLD progression. Changes in plasma membrane localization and zonal distribution of BA transporters can inf
Externí odkaz:
https://doaj.org/article/aac573e3c0734319af4532863a1f9a55
Autor:
Oliver Glass, Daniel Liu, Elizabeth Bechard, Cynthia D. Guy, Jane Pendergast, Anna Mae Diehl, Manal F. Abdelmalek
Publikováno v:
Hepatology Communications, Vol 6, Iss 2, Pp 334-344 (2022)
Exercise is a foundational treatment for nonalcoholic fatty liver disease (NAFLD); however, the majority of patients are unable to initiate and maintain effective exercise habits and remain at increased risk for progressive liver disease. Barriers an
Externí odkaz:
https://doaj.org/article/0754ff572f954669987544ab843d6327
Sex and Menopause Modify the Effect of Single Nucleotide Polymorphism Genotypes on Fibrosis in NAFLD
Autor:
Kara Wegermann, Melanie E. Garrett, Jiayin Zheng, Andrea Coviello, Cynthia A. Moylan, Manal F. Abdelmalek, Shein‐Chung Chow, Cynthia D. Guy, Anna Mae Diehl, Allison Ashley‐Koch, Ayako Suzuki
Publikováno v:
Hepatology Communications, Vol 5, Iss 4, Pp 598-607 (2021)
The development of fibrosis in nonalcoholic fatty liver disease (NAFLD) is influenced by genetics, sex, and menopausal status, but whether genetic susceptibility to fibrosis is influenced by sex and reproductive status is unclear. Our aim was to iden
Externí odkaz:
https://doaj.org/article/b7925e634c3749e48299369bbda597e9
Autor:
Kara Wegermann, Catherine Howe, Ricardo Henao, Ying Wang, Cynthia D. Guy, Manal F. Abdelmalek, Anna Mae Diehl, Cynthia A. Moylan
Publikováno v:
Hepatology Communications, Vol 5, Iss 4, Pp 608-617 (2021)
Identifying patients at higher risk for poor outcomes from nonalcoholic fatty liver disease (NAFLD) remains challenging. Metabolomics, the comprehensive measurement of small molecules in biological samples, has the potential to reveal novel noninvasi
Externí odkaz:
https://doaj.org/article/8827ebe784e343ad945032872f158e20
Autor:
Shikha S. Sundaram, Marzena Swiderska‐Syn, Ronald J. Sokol, Ann C. Halbower, Kelley E. Capocelli, Zhaoxing Pan, Kristen Robbins, Brian Graham, Anna Mae Diehl
Publikováno v:
Hepatology Communications, Vol 3, Iss 7, Pp 883-893 (2019)
Chronic intermittent hypoxia and hedgehog (Hh) pathway dysregulation are associated with nonalcoholic fatty liver disease (NAFLD) progression. In this study, we determined the relationship between obstructive sleep apnea (OSA)/nocturnal hypoxia and H
Externí odkaz:
https://doaj.org/article/d1840ce736084002a5ee66b931118c9b
Autor:
Oliver Glass, Ricardo Henao, Keyur Patel, Cynthia D. Guy, Hans J. Gruss, Wing‐Kin Syn, Cynthia A. Moylan, Robert Streilein, Russell Hall, Anna Mae Diehl, Manal F. Abdelmalek
Publikováno v:
Hepatology Communications, Vol 2, Iss 11, Pp 1344-1355 (2018)
The severity of hepatic fibrosis is the primary predictor of liver‐related morbidity and mortality in patients with nonalcoholic fatty liver disease (NAFLD). Unfortunately, noninvasive serum biomarkers for NAFLD‐associated fibrosis are limited. W
Externí odkaz:
https://doaj.org/article/15c5b601b1564633b905485bbd685159
Autor:
Sarah E. Kleinstein, Matthew Rein, Manal F. Abdelmalek, Cynthia D. Guy, David B. Goldstein, Anna Mae Diehl, Cynthia A. Moylan
Publikováno v:
Hepatology Communications, Vol 2, Iss 9, Pp 1021-1029 (2018)
Abstract Nonalcoholic fatty liver disease (NAFLD) is a heterogeneous disease with highly variable outcomes. Patients with simple steatosis typically experience a benign course, whereas those with more advanced liver injury, nonalcoholic steatohepatit
Externí odkaz:
https://doaj.org/article/2a83b6bb981c4ad98bdc25157f8217b4