Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Tim D. Spector"'
Autor:
Kristina Åkesson, Fiona E. McGuigan, John Blangero, Melanie A. Carless, Ching-Ti Liu, Candace M. Kammerer, François Rousseau, Dongbing Lai, Munro Peacock, Audrey C. Choh, Sylvie Giroux, David Karasik, Tatiana Foroud, Beate St Pourcain, Bradford Towne, David M. Evans, Howard J. Edenberg, Jonathan H Tobias, John P. Kemp, Braxton D. Mitchell, Daniel L. Koller, Debbie A Lawlor, J. Brent Richards, Tim D. Spector, George McMahon, David Goltzman, Laura M. Yerges-Armstrong, Jerilynn C. Prior, Christopher S. Kovacs, Stefan A. Czerwinski, Douglas P. Kiel, Michael J. Econs, Nicholas J. Timpson, Hou-Feng Zheng
Publikováno v:
Journal of Bone and Mineral Research; Vol 28
Previous genome-wide association studies (GWAS) have identified common variants in genes associated with variation in bone mineral density (BMD), although most have been carried out in combined samples of older women and men. Meta-analyses of these r
Autor:
Isabel Kolm, Julia Newton-Bishop, Miquel Angel Pujana, Josep Malvehy, Cristina Carrera, Mark Harland, Andrew A. Brown, Fay Elliot, Mark M. Iles, Veronique Bataille, Nuria Bonifaci, May Chan, Zighereda Ogbah, Joan Anton Puig-Butille, Daniel Glass, Elisabet Guino, Celia Badenas, Tim Bishop, Julie Randerson-Moor, Susana Puig, Tim D. Spector
Publikováno v:
Pigment Cell & Melanoma Research; Vol 26
Summary The presence of a high nevus number is the strongest phenotypic predictor of melanoma risk. Here, we describe the results of a three-stage study directed at identifying risk variants for the high nevus phenotype. At the first stage, 263 melan
Publikováno v:
Annals of Human Genetics; Vol 76
Annals of Human Genetics
Annals of Human Genetics
Summary The association of FTO gene variants with body mass index (BMI) and other obesity characteristics is well established. However, uncertainties remain whether the association is present only in young populations and whether it is attributable t
Autor:
Yixue Li, Tao Xu, Eva Lattka, Joachim Heinrich, Jerzy Adamski, Zhonghao Yu, Werner Römisch-Margl, Paula Singmann, Karsten Suhre, Thomas Illig, Tim D. Spector, Guangju Zhai, Rui Wang-Sattler, Ying He, Elisabeth Thiering, Annette Peters, Heinz-Erich Wichmann, Kirstin Mittelstraß, Marie Standl, Nicole Soranzo, Cornelia Prehn, Christian Gieger
Publikováno v:
Aging Cell; Vol 11
Aging Cell
Aging Cell
Understanding the complexity of aging is of utmost importance. This can now be addressed by the novel and powerful approach of metabolomics. However, to date, only a few metabolic studies based on large samples are available. Here, we provide novel a
Autor:
Harold Snieder, Sandra D. O'Dell, Theodosios Kyriakou, Ramasamyiyer Swaminathan, Sakina B. Gooljar, Dongliang Ge, Laura J. Collins, Tim D. Spector
Publikováno v:
Obesity, 16(2), 492-496. Wiley-Blackwell
The leptin signal is transduced via the JAK2-STAT3 (Janus kinase 2-signal transducer and activator of transcription-3) pathway at the leptin receptor. JAK2 also phosphorylates insulin receptor substrate, integral to insulin and leptin action and is r
Autor:
Ana M. Valdes, John Loughlin, Mark Van Oene, Kay Chapman, Gabriela L. Surdulescu, Michael Doherty, Tim D. Spector
Publikováno v:
Arthritis & Rheumatism; Jan2007, Vol. 56 Issue 1, p137-146, 10p
Autor:
Frances M. K. Williams, Toby Andrew, Tore Saxne, Dick Heinegard, Tim D. Spector, Alex J. MacGregor
Publikováno v:
Arthritis & Rheumatism; Jul2006, Vol. 54 Issue 7, p2147-2151, 5p
Publikováno v:
Arthritis & Rheumatism; Mar2006, Vol. 54 Issue 4, p1051-1054, 4p
Autor:
Tim D. Spector, Richard H. Reneland, Steven Mah, Ana M. Valdes, Deborah J. Hart, Stefan Kammerer, Maria Langdown, Carolyn R. Hoyal, Josephine Atienza, Michael Doherty, Proton Rahman, Matthew R. Nelson, Andreas Braun
Publikováno v:
Arthritis & Rheumatism; Feb2006, Vol. 54 Issue 2, p524-532, 9p
Autor:
Ana M. Valdes, Mark Van Oene, Deborah J. Hart, Gabriela L. Surdulescu, John Loughlin, Michael Doherty, Tim D. Spector
Publikováno v:
Arthritis & Rheumatism; Feb2006, Vol. 54 Issue 2, p533-539, 7p