Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Mahadevan Rajasekaran"'
Autor:
Jesse W. Tai, Raag Bhargava, Mahadevan Rajasekaran, Ho-Song Yu, Weg M. Ongkeko, Abinav T. Chilukuri, Rucha Deshpande, Wei Li, Valmik Bhargava
Publikováno v:
Neurourology and Urodynamics. 39:625-632
Aim To elucidate the precise cellular and molecular mechanisms that underlie urethral fibrogenesis. Methods Endoluminal electrocautery injury (using Karl Storz 10 Fr. Pediatric urethroscope) was employed in male rabbits (n = 6) to create mucosal inju
Autor:
Shantanu Sinha, Mahadevan Rajasekaran, Valmik Bhargava, Usha Sinha, Vadim Malis, Kyoko Sakamoto
Publikováno v:
Journal of Magnetic Resonance Imaging. 48:1002-1011
BACKGROUND Urinary incontinence is a major clinical problem arising primarily from age-related degenerative changes to the sphincter muscles. However, the precise anatomy of the normal male sphincter muscles has yet to be established. Diffusion tenso
Publikováno v:
BJU International. 106:572-577
OBJECTIVE To evaluate, in a well-controlled study, the effect of surgically induced partial bladder outlet obstruction (PBOO) on male erectile function in a rat model. MATERIALS AND METHODS PBOO was created in 17 adult male Sprague-Dawley rats by par
Publikováno v:
BJU International. 98:430-434
OBJECTIVE To evaluate the effects of MN-001, a novel orally active anti-inflammatory agent, in suppressing the bladder hyperactivity resulting from ovalbumin (OA)-induced mast-cell stimulation in a rat model. MATERIALS AND METHODS Sprague-Dawley rats
Publikováno v:
Neurourology and Urodynamics. 24:295-300
Aims Spontaneously hypertensive rats (SHR) exhibit overactive bladder (OAB) symptoms and have an up-regulated calcium sensitizing RhoA/Rho-kinase pathway in their vascular smooth muscle tissues. This study examined the role of RhoA/Rho-kinase pathway
Publikováno v:
Neurogastroenterology & Motility. 23:70-e7
Background Our recent studies show that the external anal sphincter muscle (EAS) operates at a sarcomere length range which is below optimal. In this study, we tested the hypothesis that by surgically increasing sarcomere length and bringing it close