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pro vyhledávání: '"Jonathan Hall"'
Autor:
Jonathan Hall, Malcolm Butler
Publikováno v:
School Science and Mathematics. 122:286-297
Autor:
Alyssa C. Hill, Jonathan Hall
Publikováno v:
Helvetica Chimica Acta, 106 (3)
In an article published by Helvetica Chimica Acta in 1995, chemist P. Martin describes the synthesis of 2′-O-alkylated ribonucleosides for use in therapeutic antisense oligonucleotides (ASOs). This work was motivated by the need for a modified ribo
Publikováno v:
ChemBioChem, 22 (21)
Chembiochem
Chembiochem
RNA is an emerging platform for drug delivery, but the susceptibility of RNA to nuclease degradation remains a major barrier to its implementation in vivo. Here, we engineered flaviviral Xrn1-resistant RNA (xrRNA) motifs to host small interfering RNA
Publikováno v:
Chemistry (Weinheim an Der Bergstrasse, Germany)
MicroRNAs constitute a class of endogenous, non‐coding RNAs that influence various processes within the cell. By base‐pairing to partially‐complementary sites located in the 3’ untranslated region of target messenger RNAs, microRNAs participa
Publikováno v:
Helvetica Chimica Acta. 102
Publikováno v:
Political Psychology. 39:345-363
Transitional justice has emerged to address victims' needs as a means of restoring relations broken by violence. Yet we know little about victims' attitudes towards different transitional justice mechanisms. Why do some victims prioritize retributive
Autor:
Yuluan Wang, Mirjam Menzi, Matteo Fischer, Fabienne Baumann, Ugo Pradere, Jonathan Hall, Martina Bigatti
Publikováno v:
ChemBioChem. 17:2012-2017
Functionalized oligoribonucleotides are essential tools in RNA chemical biology. Various synthetic routes have been developed over recent years to conjugate functional groups to oligoribonucleotides. However, the presence of the functional group on t
Autor:
Jonathan Hall, Evangelia Lekka
Publikováno v:
FEBS Letters, 592 (17)
Febs Letters
Febs Letters
Noncoding RNAs are emerging as potent and multifunctional regulators in all biological processes. In parallel, a rapidly growing number of studies has unravelled associations between aberrant noncoding RNA expression and human diseases. These associa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43bf4fab5e8293fb345452b9d6e7a9d8
https://hdl.handle.net/20.500.11850/289919
https://hdl.handle.net/20.500.11850/289919
Autor:
Martina Roos, Matije Lucic, Ugo Pradere, Jonathan Hall, Andreas Brunschweiger, Luca F R Gebert
Publikováno v:
Angewandte Chemie-International Edition
and other related fields. Most applicationsinvolve relatively short DNAs and RNAs; however thedemand for labeled long RNA (>60 nt) has increased inline with our growing appreciation of a rich, only partiallyunderstood biology of structured non-coding
Publikováno v:
ChemBioChem
Long term relationship: Biotin labels on RNAs and possibly other biomacromolecules are easily oxidized causing a dramatic loss of affinity for streptavidin and adversely affecting the measurement of high affinity interactions. A new SPR method has be