Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Conrad Leonard"'
Autor:
James S. Wilmott, Peter Johansson, Oliver Holmes, Qinying Xu, Peter M. Ferguson, Kerwin F. Shannon, Ann-Marie Patch, Richard F. Kefford, John V. Pearson, Andrew J. Spillane, Nicholas K. Hayward, Conrad Leonard, Graham J. Mann, Felicity Newell, Stephen H. Kazakoff, Katia Nones, Camelia Quek, Nicola Waddell, Ping Shang, Jonathan R. Stretch, Richard A. Scolyer, Alexander M. Menzies, John F. Thompson, Scott Wood, Georgina V. Long, Robyn P. M. Saw, Antonia L. Pritchard
Publikováno v:
International Journal of Cancer. 144:1049-1060
Cutaneous melanoma accounts for at least >10% of all cancers in adolescents and young adults (AYA, 15–30 years of age) in Western countries. To date, little is known about the correlations between germline variants and somatic mutations and mutatio
Autor:
Mythily Mariasegaram, Ann-Marie Patch, Conrad Leonard, Admire Matsika, Sean M. Grimmond, Fares Al-Ejeh, Margaret C. Cummings, Rosalind L. Jeffree, Georgia Chenevix-Trench, Oliver Holmes, Leonard Da Silva, Nur Aishah Taib, Adrienne M. Flanagan, Teresa K. Withers, Matthew J. Anderson, Vairavan Narayanan, Ehsan Nourbakhsh, Queenie Lau, Sunil R. Lakhani, J. Lynn Fink, kConFab, Felicity Newell, Katia Nones, Stephen H. Kazakoff, Colleen Niland, Parmjit S. Jat, Ivon Harliwong, Peter T. Simpson, Lynne Reid, Nicola Waddell, Soo Hwang Teo, Karin S. Kassahn, Sebastian Brandner, John V. Pearson, Nick Waddell, Qinying Xu, Scott Wood, Darrin Taylor, Senel Idrisoglu, Peter Wilson, Timothy J. C. Bruxner, Kum Kum Khanna, Craig Nourse, Shivangi Wani, Angelika N. Christ, David Miller, Amy E. McCart Reed, Michael C.J. Quinn, Yock Ping Chow, Jodi M. Saunus, Suzanne Manning, Peter Bailey
Publikováno v:
The Journal of Pathology. 237:363-378
Treatment options for patients with brain metastases (BMs) have limited efficacy and the mortality rate is virtually 100%. Targeted therapy is critically under-utilized, and our understanding of mechanisms underpinning metastatic outgrowth in the bra
Autor:
Lynn Fink, Sean M. Grimmond, Ann-Marie Patch, Sarah Song, Jianmin Wu, Amber L. Johns, Giovanni Butturini, Karin S. Kassahn, Conrad Leonard, Michelle Thomas, Marina Pajic, Rita T. Lawlor, Clare Watson, Suzanne Manning, Vincenzo Corbo, Giuseppe Zamboni, Anna Malpaga, Mark J. Cowley, Stephen H. Kazakoff, David Miller, Craig Nourse, Ilse Rooman, David L. A. Wood, Stefano Crippa, Nic Waddell, Anthony J. Gill, Peter Bailey, Paola Castelli, Katia Nones, Andrew V. Biankin, Massimo Falconi, Angelika N. Christ, Aldo Scarpa, Mark Pinese, John V. Pearson, Marc D. Jones, Darrin Taylor, David K. Chang
Publikováno v:
International Journal of Cancer. 135:1110-1118
The importance of epigenetic modifications such as DNA methylation in tumorigenesis is increasingly being appreciated. To define the genome-wide pattern of DNA methylation in pancreatic ductal adenocarcinomas (PDAC), we captured the methylation profi