Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Chris I. De Zeeuw"'
Autor:
Chris I. De Zeeuw, Barthold N. Schüttenhelm, Pieter A. van Doorn, Tiziana Pederzani, Malik Bechakra, Joost L M Jongen
Publikováno v:
Journal of Comparative Neurology, 525(17), 3757-3768. Wiley-Liss Inc.
Journal of Comparative Neurology, 525, 3757-3768. Wiley-Liss Inc.
Journal of Comparative Neurology, 525, 3757-3768. Wiley-Liss Inc.
Skin biopsies from patients with neuropathic pain often show changes in epidermal innervation, although it remains to be elucidated to what extent such changes can be linked to a particular subgroup of nerve fibers and how these changes are correlate
Publikováno v:
The Journal of Physiology. 595:5301-5326
Compensatory eye movements elicited by head rotation, also known as vestibulo-ocular reflex (VOR), can be adapted with the use of visual feedback. The cerebellum is essential for this type of movement adaptation, but its neuronal correlates remain to
Autor:
Mark E. Ladd, Markus Thürling, Stefan Maderwald, Henk-Jan Boele, Thomas Ernst, Jörn Diedrichsen, Dagmar Timmann, Marc Schlamann, Fabian Kahl, Sarah Müller, Chris I. De Zeeuw, Sebastiaan K. E. Koekkoek
Publikováno v:
Human Brain Mapping. 38:3957-3974
Classical delay eyeblink conditioning is likely the most commonly used paradigm to study cerebellar learning. As yet, few studies have focused on extinction and savings of conditioned eyeblink responses (CRs). Saving effects, which are reflected in a
Autor:
Guillermo Federico Spitzmaul, Martijn Schonewille, William Wisden, Chris I. De Zeeuw, Patricia Seja, Thomas J. Jentsch, Ilse Klein, Aleksandra Badura, Christian A. Hübner, York Rudhard
Publikováno v:
The EMBO Journal. 31:1217-1230
Cerebellar cortical throughput involved in motor control comprises granule cells (GCs) and Purkinje cells (PCs), both of which receive inhibitory GABAergic input from interneurons. The GABAergic input to PCs is essential for learning and consolidatio
Publikováno v:
Otolaryngology: head and neck surgery, 146, 448-454. Mosby Inc.
Otolaryngology and Head and Neck Surgery, 146(3), 448-454. SAGE Publishing
Otolaryngology and Head and Neck Surgery, 146(3), 448-454. SAGE Publishing
Objective. To determine the functional recovery in patients with severe transient peripheral facial motor paralysis (Bell palsy). Study Design. Prospective controlled trial. Setting. Academic medical center. Subjects and Methods. Blink recovery was s
Autor:
Froukje Zandstra, Jornt R. De Gruijl, Sebastiaan K. E. Koekkoek, Joel Shapiro, Barry Van Der Ende, Laurens W. J. Bosman, Tom J. H. Ruigrok, Cullen B. Owens, Chris I. De Zeeuw, Jan-Willem Potters, B. F. M. Rijken
Publikováno v:
The Journal of Physiology. 588:3757-3783
The cerebellar cortex is crucial for sensorimotor integration. Sensorimotor inputs converge on cerebellar Purkinje cells via two afferent pathways: the climbing fibre pathway triggering complex spikes, and the mossy fibre–parallel fibre pathway, mo
Endocochlear potential depends on Cl− channels: mechanism underlying deafness in Bartter syndrome IV
Autor:
Thomas J. Jentsch, Nicola Strenzke, Hannes Maier, Adrian Muenscher, Corina E. Andreescu, Gesa Rickheit, Chris I. De Zeeuw, Anselm A. Zdebik
Publikováno v:
The EMBO journal, 27(21): 2809-2942
Human Bartter syndrome IV is an autosomal recessive disorder characterized by congenital deafness and severe renal salt and fluid loss. It is caused by mutations in BSND, which encodes barttin, a beta-subunit of ClC-Ka and ClC-Kb chloride channels. I
Autor:
Barbara A. Bohne, Chris I. De Zeeuw, Patrick L. M. Huygen, M. Wagenaar, Tama Hasson, Sebastiaan K. E. Koekkoek, Casper C. Hoogenraad, Adriaan M. van Alphen, John C. Sun
Publikováno v:
Annals of the New York Academy of Sciences. 942:493-496
Identification of genes involved in hereditary vestibular disease is growing at a remarkable pace. Mutant mouse technology can be an important tool for understanding the biological mechanism of human vestibular diseases.
Publikováno v:
European Journal of Neuroscience, 19, 2915-2922. Wiley-Blackwell Publishing Ltd
The homeostasis of intracellular Cl(-) concentration ([Cl(-)](i)) is critical for neuronal function, including gamma-aminobutyric acid (GABA)ergic synaptic transmission. Here, we investigated activity-dependent changes in [Cl(-)](i) using a transgene
Autor:
Chris I. De Zeeuw, Klaus Willecke, Joachim Degen, Carola Meier, Rolf Dermietzel, Stephanie Urschel, Goran Söhl, Elisabeth Petrasch-Parwez, Ruben S. Van Der Giessen, Karl Schilling
Publikováno v:
Journal of Comparative Neurology. 473:511-525
Targeted deletion of the connexin36 (Cx36) gene in the mouse genome leads to visual transmission defects, weakened synchrony of rhythmic inhibitory potentials in the neocortex, and disruption of -frequency network oscillations. We have generated tran