Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Amer H. Zureikat"'
Autor:
Samer S. AlMasri, Mazen S. Zenati, Annissa Desilva, Ibrahim Nassour, Brian A. Boone, Aatur D. Singhi, David L. Bartlett, Lance A. Liotta, Virginia Espina, Patricia Loughran, Michael T. Lotze, Alessandro Paniccia, Herbert J. Zeh III, Amer H. Zureikat, Nathan Bahary
Publikováno v:
Cancer Medicine, Vol 10, Iss 20, Pp 7233-7241 (2021)
Abstract Introduction Preoperative autophagy inhibition with hydroxychloroquine (HCQ) in combination with gemcitabine in pancreatic adenocarcinoma (PDAC) has been shown to be safe and effective in inducing a serum biomarker response and increase rese
Externí odkaz:
https://doaj.org/article/22bcc880a5264081a326a90968f1c5d6
Autor:
Naomi Fei, Sijin Wen, Rajesh Ramanathan, Melissa E. Hogg, Amer H. Zureikat, Michael T. Lotze, Nathan Bahary, Aatur D. Singhi, Herbert J. Zeh, Brian A. Boone
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 5, Pp 1822-1829 (2021)
Abstract SMAD4, a tumor suppressor gene, is lost in up to 60%–90% of pancreatic adenocarcinomas (PDAs). Loss of SMAD4 allows tumor progression by upregulating autophagy, a cell survival mechanism that counteracts apoptosis and allows intracellular
Externí odkaz:
https://doaj.org/article/fc1b523b0b3a44e2a592d00a88565d98
Autor:
Amer H. Zureikat, Ibrahim Nassour, David L Bartlett, Annissa Desilva, Lance A. Liotta, Aatur D. Singhi, Virginia Espina, Alessandro Paniccia, Samer AlMasri, Nathan Bahary, Brian A. Boone, Herbert J. Zeh, Patricia Loughran, Michael T. Lotze, Mazen S. Zenati
Publikováno v:
Cancer Medicine
Cancer Medicine, Vol 10, Iss 20, Pp 7233-7241 (2021)
Cancer Medicine, Vol 10, Iss 20, Pp 7233-7241 (2021)
Introduction Preoperative autophagy inhibition with hydroxychloroquine (HCQ) in combination with gemcitabine in pancreatic adenocarcinoma (PDAC) has been shown to be safe and effective in inducing a serum biomarker response and increase resection rat
Autor:
Nathan Bahary, Naomi Fei, Rajesh Ramanathan, Melissa E. Hogg, Sijin Wen, Brian A. Boone, Herbert J. Zeh, Amer H. Zureikat, Aatur D. Singhi, Michael T. Lotze
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 5, Pp 1822-1829 (2021)
Clinical and Translational Science
Clinical and Translational Science
SMAD4, a tumor suppressor gene, is lost in up to 60%–90% of pancreatic adenocarcinomas (PDAs). Loss of SMAD4 allows tumor progression by upregulating autophagy, a cell survival mechanism that counteracts apoptosis and allows intracellular recycling
Autor:
Alessandro Paniccia, Nathan Bahary, David L Bartlett, Kenneth K. Lee, Kenneth J. Smith, Amer H. Zureikat, Caroline J. Rieser, Sowmya Narayanan
Publikováno v:
J Surg Oncol
INTRODUCTION: Neoadjuvant therapy (NAT) is an emerging strategy for operable pancreatic ductal adenocarcinoma (PDAC). While neoadjuvant therapy increases multimodal therapy completion, it risks functional decline and treatment drop out. We used decis
Autor:
Brian A. Boone, Kelsey A. Musgrove, Carl Schmidt, Alan A Thomay, Pavan Rao, Britney R. Harris, Melissa E. Hogg, Herbert J. Zeh, Amer H. Zureikat, J. Wallis Marsh
Publikováno v:
J Surg Oncol
Introduction The learning curve associated with robotic pancreatoduodenectomy (RPD) is a hurdle for new programs to achieve optimal results. Since early analysis, robotic training has recently expanded, and the RPD approach has been refined. The purp
Autor:
Alessandro Paniccia, Ibrahim Nassour, Samer AlMasri, Samer Tohme, Amer H. Zureikat, Kenneth K. Lee, David L. Bartlett, Richard S. Hoehn, Mohamed A. Adam
Publikováno v:
Journal of Surgical Oncology. 122:707-715
Background Open extended cholecystectomy (O-EC) has long been the recommended treatment for resectable gallbladder cancer (GBC), while the minimally-invasive approach for EC (MIS-EC) remains controversial. Our aim was to analyze overall survival of G
Autor:
Jill Krejdovsky, Mary Helen Black, James Ohr, Holly LaDuca, Mary Linton B. Peters, A. James Moser, Arlene Colvin, Nadine Tung, Eve Karloski, Jill S. Dolinsky, Weijing Sun, Virginia Speare, John C. Rhee, Nathan Bahary, Kim DeLeonardis, Melissa E. Hogg, Amer H. Zureikat, Kenneth H. Lee, James Cheng Yen Lee, Randall E. Brand, Beth Dudley, Allan Tsung, Herbert J. Zeh, Lindsey Stobie, Erkut Borazanci, Cynthia Lim, Emily Dalton
Publikováno v:
Cancer. 124:3520-3527
BACKGROUND The objective of this study was to investigate the prevalence of pathogenic germline variants (PGVs) in 32 cancer susceptibility genes in individuals with newly diagnosed pancreatic ductal adenocarcinoma (PDAC). A key secondary objective w
Autor:
Melissa E. Hogg, David L. Bartlett, Aatur D. Singhi, Steven A. Ahrendt, Haroon A. Choudry, Mashaal Dhir, James F. Pingpank, Herbert J. Zeh, Nathan Bahary, Matthew P. Holtzman, Amer H. Zureikat
Publikováno v:
Cancer Medicine
The impact of genomic profiling on the outcomes of patients with advanced gastrointestinal (GI) malignancies remains unknown. The primary objectives of the study were to investigate the clinical benefit of genomic‐guided therapy, defined as complet
Autor:
Jennifer Steve, Heather L. Jones, Mazen S. Zenati, Samantha Perkins, James F. Pingpank, Melissa E. Hogg, Haroon A. Choudry, Herbert J. Zeh, David L. Bartlett, Mashaal Dhir, Amber K. Clifford, Matthew P. Holtzman, Amer H. Zureikat, James C. Padussis
Publikováno v:
Journal of Surgical Oncology. 114:342-347
Background Hepatic artery infusion (HAI) chemotherapy can be combined with systemic chemotherapy for the treatment of isolated unresectable colorectal liver metastases (IU-CRLM) and intrahepatic cholangiocarcinoma (U-ICC). However, HAI pump placement