Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Christopher L.-H. Huang"'
Publikováno v:
Annals of the New York Academy of Sciences. 1116:255-270
This review compares ryanodine receptor (RyR)-mediated Ca(2+) signaling processes in muscle and osteoclast cells. In muscle, RyR-mediated release of an intracellularly stored, sarcoplasmic reticular (SR), Ca(2+) is triggered by voltage-sensitive dihy
Calcium sensing and cell signaling processes in the local regulation of osteoclastic bone resorption
Publikováno v:
Biological Reviews. 79:79-100
The skeletal matrix in terrestrial vertebrates undergoes continual cycles of removal and replacement in the processes of bone growth, repair and remodeling. The osteoclast is uniquely important in bone resorption and thus is implicated in the pathoge
Autor:
Frances E. Lund, Mone Zaidi, Peter J. R. Bevis, Christopher L.-H. Huang, Jameel Iqbal, Baljit S. Moonga, Li Sun, Harry C. Blair, Olugbenga A. Adebanjo, Xue-Bin Wu, Etsuko Abe, Svetlana Dolgilevich, Tony Yuen
Publikováno v:
The FASEB Journal. 17:369-375
We have evaluated the role of the ADP-ribosyl cyclase, CD38, in bone remodeling, a process by which the skeleton is being renewed constantly through the coordinated activity of osteoclasts and osteoblasts. CD38 catalyzes the cyclization of its substr
Autor:
Mone Zaidi, Bridget E. Bax, David R. Blake, A. S. M. Towhidul Alam, V.S. Shankar, Christopher M.R. Bax, Baljit S. Moonga, Clifford Robert Stevens, Christopher L.-H. Huang, Peter J.R. Bevis, Michael Pazianas
Publikováno v:
Biological Reviews. 68:197-264
Summary Past knowledge and the recent developments on the formation, activation and mode of action of osteoclasts, with particular reference to the regulation of each individual step, have been reviewed. The following conclusions of consensus have em
Publikováno v:
Experimental Physiology. 78:183-196
We have performed a set of independent studies on the effects of the circulating pancreatic polypeptide, amylin, on rat osteoclast function, in vitro. Time-lapse video observations, measuring cell protrusions and retraction, showed that 250 nmol l-1
Autor:
Mone Zaidi, Harish K. Datta, Iain MacIntyre, P. J. R. Bevis, Baljit S. Moonga, Christopher L.-H. Huang
Publikováno v:
Experimental Physiology. 76:923-933
The effects of perchlorate anion (ClO4-) on osteoclast properties were investigated through a number of independent in vivo and in vitro procedures. Intravenous infusion of ClO4- significantly reduced plasma [Ca] in young (50 g) Wistar rats, in the a
Publikováno v:
Biological Reviews.
Vertebrate skeletal differentiation retains elements from simpler phyla, and reflects the differentiation of supporting tissues programmed by primary embryonic development. This developmental scheme is driven by homeotic genes expressed in sequence,