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pro vyhledávání: '"Christopher L.-H. Huang"'
Autor:
Anders Riisager, Christopher L.-H. Huang, Rudy M Duehmke, Ole Bækgaard Nielsen, Thomas Holm Pedersen
Publikováno v:
The Journal of Physiology. 592:4417-4429
Recent studies in rat muscle fibres show that repetitive firing of action potentials causes changes in fibre resting membrane conductance (Gm) that reflect regulation of ClC-1 Cl(-) and KATP K(+) ion channels. Methodologically, these findings were ob
Publikováno v:
Biological Reviews. 84:143-159
Regulation of cell volume is a fundamental property of all animal cells and is of particular importance in skeletal muscle where exercise is associated with a wide range of cellular changes that would be expected to influence cell volume. These compl
Publikováno v:
Annals of the New York Academy of Sciences. 1116:255-270
This review compares ryanodine receptor (RyR)-mediated Ca(2+) signaling processes in muscle and osteoclast cells. In muscle, RyR-mediated release of an intracellularly stored, sarcoplasmic reticular (SR), Ca(2+) is triggered by voltage-sensitive dihy
Publikováno v:
The Journal of Physiology. 582:467-470
We would like to thank Dr Kemp for his letter regarding our recent paper (Usher-Smith et al. 2006). His work is in some respects complimentary to our original paper, in that it attempts to provide an analytic study of some of the processes that we mo
Publikováno v:
The Journal of Physiology. 564:51-63
The influence of extracellular hypotonicity on the relationship between cell volume (Vc) and resting membrane potential (Em) was investigated in Rana temporaria skeletal muscle. Vc was measured by confocal microscope imaging of fibres through their t
Autor:
James A. Fraser, Christof J. Schwiening, Claire E. Middlebrook, Juliet A. Usher-Smith, Christopher L.-H. Huang
Publikováno v:
The Journal of Physiology. 563:745-764
The relationship between cell volume (Vc) and membrane potential (Em) in Rana temporaria striated muscle fibres was investigated under different conditions of intracellular acidification. Confocal microscope xz-scanning monitored the changes in Vc, w
Publikováno v:
The Journal of Physiology. 559:459-478
This paper quantifies recent experimental results through a general physical description of the mechanisms that might control two fundamental cellular parameters, resting potential (Em) and cell volume (Vc), thereby clarifying the complex relationshi
Autor:
Emily A. Ferenczi, James A. Fraser, Jeremy N. Skepper, Christopher L.-H. Huang, Sangeeta Chawla, Christof J. Schwiening
Publikováno v:
The Journal of Physiology. 555:423-438
This study investigated membrane transport mechanisms influencing relative changes in cell volume (V) and resting membrane potential (Em) following osmotic challenge in amphibian skeletal muscle fibres. It demonstrated a stabilization of Em despite c
Autor:
Christopher L.-H. Huang
Publikováno v:
The Journal of Physiology. 501:589-606
1. The effects of graded concentrations of tetracaine on the steady-state and kinetic properties of intramembrane charge were examined in intact voltage-clamped amphibian muscle fibres. 2. The micromolar tetracaine concentrations that were hitherto r
Autor:
Christopher L.-H. Huang
Publikováno v:
The Journal of Physiology. 313:207-222
1. Voltage clamp experiments on muscle fibres compared transients to 10 mV steps at hyperpolarized voltages between VT = -100 to -185 mV with controls obtained at VC = -85 mV. 2. Membrane capacitance fell by 15%, 13% and 4.5% per 100 mV hyperpolariza