Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Silva DA"'
Autor:
Humberto Fonseca de Freitas, Carlos Alfredo Lopes de Carvalho, Samuel Silva da Rocha Pita, Antônio Leandro da Silva Conceição, Luciana S. Freitas, Demian R. Ifa, Alexsandro Branco, Alexandre M. Pinheiro, Ângela C. de O. Lima, Rodrigo Souza Conceição
Publikováno v:
Chemical Biology & Drug Design. 98:1104-1115
Tetragonisca angustula honey was fractioned in a SiO2 column to furnish three fractions (A-C) in which four hydroxycinnamic acid-Spermidine amides (HCAAs), known as N', N″, N‴-tris-p-coumaroyl spermidine, N', N″-dicaffeoyl, N‴-coumaroyl sperm
Autor:
Aline Rigon Zimmer, Sergio T. Ferreira, Igor C. Fontana, Diogo O. Souza, Grace Gosmann, Andreia Silva da Rocha, Eduardo R. Zimmer, Mychael V. Lourenco
Publikováno v:
Journal of Neurochemistry. 155:348-369
Amyloid-β (Aβ) dysmetabolism is tightly associated with pathological processes in Alzheimer's disease (AD). Currently, it is thought that, in addition to Aβ fibrils that give rise to plaque formation, Aβ aggregates into non-fibrillar soluble olig
Autor:
Samuel Silva da Rocha Pita, Elda Gonçalves dos Santos, André A. Vieira, Ivo Santana Caldas, Lucas Silva Abreu, Eliane de Oliveira Silva, Amanda Santos Gusmão, Josean Fechine Tavares, Humberto Fonseca de Freitas
Publikováno v:
Chemistry & Biodiversity. 18
Hundreds of millions of people worldwide are affected by Chagas' disease caused by Trypanosoma cruzi. Since the current treatment lack efficacy, specificity, and suffers from several side-effects, novel therapeutics are mandatory. Natural products fr
Autor:
Wladymyr Jefferson Bacalhau de Sousa, Rogério Lacerda-Santos, Rosana Araújo Rosendo, Elizandra Silva da Penha, Erik Montagna, Luanna Abílio Diniz Melquíades de Medeiros, Millena de Oliveira Firmino, Marcus Vinícius Lia Fook, Antonielson dos Santos
Publikováno v:
Microscopy Research and Technique.
The focus of this triple-blind study was on evaluating the effect of chitosan combined with Dysphania ambrosioides (A) extract on the bone repair process in vivo. In total, 60 male Wistar rats (Rattus norvegicus albinus) weighing between 260 and 270
Autor:
José Daniel Figueroa Villar, Lucas Villas Bôas Hoelz, Maria de Nazaré Correia Soeiro, Aline Nefertiti Silva da Gama, Fábio de Vasconcellos Fontes, D. G. J. Batista, Patrícia Bernardino da Silva, Cristiane França da Silva, Nubia Boechat, Débora Inácio Leite, Maria da Conceição Avelino Dias Bianco, Mônica M. Bastos, Raiza Brandão Peres, Andressa Paula de Oliveira
Publikováno v:
Chemical Biology & Drug Design. 92:1670-1682
Chagas disease has spread throughout the world mainly because of the migration of infected individuals. In Brazil, only benznidazole (Bnz) is used; however, it is toxic and not active in the chronic phase, and cases of resistance are described. This
Autor:
Silvânia Maria Mendes Vasconcelos, Annyta Fernandes Frota, Norma Maria Barros Benevides, Valdécio Silvano Monteiro, Tarcizio Brito Santos, Rayane Siqueira de Sousa, Lissiana Magna Vasconcelos Aguiar, Luziana Mara Frota Souza, Nayara Araújo Cezario, Rodrigo Maranguape Silva da Cunha, Chistiane Oliveira Coura, Ricardo Basto Souza, Gerardo Cristino Filho
Publikováno v:
Basic & Clinical Pharmacology & Toxicology. 120:159-170
Parkinson's disease (PD) is a multifactorial disease associated with the degeneration of dopaminergic neurons and behavioural alterations. Natural bioactive compounds may provide new therapeutic alternatives for neurodegenerative disorders, such as P
Autor:
Deividi Soares, Daiana Silva Ávila, Simone Pinton, Daniel Henrique Roos, José Luiz Ribeiro Portela, Robson Luiz Puntel, Hemerson Silva da Rosa
Publikováno v:
Journal of the Science of Food and Agriculture. 97:2007-2014
BACKGROUND Studies comparing the effect of phytochemicals under different regimens of exposure are necessary to give a better indication about their mechanism(s) of protection. Hence, we propose to investigate here the preventive (pre-incubation), pr
Autor:
Débora Kélen Silva da Conceição, Vinícius Demétrio da Silva, Marly Antonia Maldaner Jacobi, Kauana Nunes de Almeida, Ítalo Ribeiro de Barros, Henri Stephan Schrekker, Sandro Campos Amico
Publikováno v:
Journal of Applied Polymer Science. 137:48702
Autor:
Eduardo R. Zimmer, Diogo Miron, Grace Gosmann, Yuri Elias Rodrigues, Aline Rigon Zimmer, Diogo O. Souza, Igor C. Fontana, Andreia Silva da Rocha
Publikováno v:
Alzheimer's & Dementia. 14
Publikováno v:
Chemical Biology & Drug Design. 80:561-571
The drugs against tropical neglected diseases, especially Chagas’ Disease, were launched more than 30 years ago, and the development of resistance requires the discovery of new and more effective chemotherapeutic agents. Trypanosoma cruzi has a red