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Autor:
Katerina Mary Zakka, Bassel F. El-Rayes, Gregory B. Lesinski, Jerome C. Landry, Ganji Purnachandra Nagaraju, Walid L. Shaib
Publikováno v:
International Journal of Cancer. 145:1529-1537
Resistance of pancreatic ductal adenocarcinoma (PDAC) to radiotherapy and chemotherapy represents a significant clinical issue. Although the mechanisms of resistance are multi-faceted, client proteins of heat shock protein 90 (HSP90) such as hypoxia