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Autor:
Keiichiro Mine, Soroku Yagihashi, Akira Takeshita, Tomoyasu Fukui, Seiho Nagafuchi, Tetsuro Kobayashi, Erika Jimbo
Publikováno v:
Journal of Diabetes Investigation. 13:435-442
Introduction The need for antiserum for immunohistochemical detection (IHC) of enterovirus (EV) in formaldehyde fixed and paraffin-embedded (FFPE) samples is increasing. The gold standard monoclonal antibody (clone 5D8/1) against EV-envelope protein
Autor:
Laurel B. Darragh, Sana D. Karam
Publikováno v:
Mol Carcinog
Presentation of tumor antigens is a critical step in producing a robust antitumor immune response. Classically tumor antigens are thought to be presented to both CD8 and CD4 T cells by professional antigen-presenting cells (pAPCs) like dendritic cell
Autor:
Stephan Sigl, Barbara Del Frari, Christoph H. Tripp, Hermann Voit, Magdalena Seidl-Philipp, Johanna Krapf, Angela An, Patrizia Stoitzner, Nikolaus Romani
Publikováno v:
Experimental Dermatology. 30:1279-1289
Dendritic cells (DC) are promising targets for immunotherapy of cancer. Clinically, immunization against cancer antigens by means of the most potent antigen-presenting cells, that is DC, remains an important treatment option in combination with the m
Publikováno v:
Transfusion
Background We previously described a mouse model in which platelet immunization between selected strains leads to production of alloantibodies and severe autoimmune thrombocytopenia and mimics the human condition posttransfusion purpura (PTP). This r
Publikováno v:
Transfusion Medicine. 31:129-135
Objectives This study evaluated the red blood cell (RBC) Lewis phenotypes by simple haemagglutination technique and molecular genotyping in healthy individuals. Background The expression of Lewis antigen on RBCs is dependent on the interaction of FUT
Autor:
Erinna F. Lee, Deng Jieru, Pamuk Bilsel, W. Douglas Fairlie, Hamsa Puthalakath, Chunni Lu, Weisan Chen, Sara Oveissi, Chuanxin Liu
Publikováno v:
FEBS J
CD4+ T cells recognize peptides presented by major histocompatibility complex class II molecules (MHC-II). These peptides are generally derived from exogenous antigens. Macroautophagy has been reported to promote endogenous antigen presentation in vi
Autor:
Keiko Ishizuka, Yukako Obata, Akihiro Takeshita, Hiroaki Furumaki, Chiaki Yamada, Naoki Nemoto, Akari Ozawa, Kinuyo Kawabata, Hiroko Watanabe, Hiroki Shibata, Harumi Fujihara, Takahito Shinba, Kaede Ino, Hitoshi Ohto
Publikováno v:
Vox Sanguinis. 116:725-734
Background and objectives Anti-CD38 monoclonal antibodies, including daratumumab and isatuximab, often interfere with pretransfusion testing. Dithiothreitol (DTT) treatment of red blood cells (RBCs) negates this interference. However, the optimum DTT
Publikováno v:
European Journal of Immunology. 51:2345-2347
The monoclonal antibody ER-TR7 was used in a great number of studies for detecting reticular fibroblasts and the ECM of lymphoid and non-lymphoid organs even if the protein recognized by the ER-TR7 antibody was not known. We have now identified nativ
Autor:
Jackeliny dos Santos Costa, Isis Indaiara Gonçalves Granjeiro Taques, Amanda Noéli da Silva Campos, Daniel Moura de Aguiar, Kuang Hongyu, Maíra F G Koiyama
Publikováno v:
Veterinary Clinical Pathology. 49:574-582
Background Immunoreactive tandem repeat proteins (TRPs) in amino acid sequences were identified and employed in the serologic diagnosis of canine monocytic ehrlichiosis (CME). Objectives This study evaluated using TRP19 and TRP36 synthetic protein an
Publikováno v:
Glia
Microglial cells are the main reservoir for HIV-1 within the brain and potential exists for negative immune checkpoint blockade therapies to purge this viral reservoir. Here, we investigated cytolytic responses of CD8(+) T lymphocytes against microgl