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Publikováno v:
The FASEB Journal. 34:13993-14005
Many factors are involved in the process of nerve regeneration. Understanding the mechanisms regarding how these factors promote an efficient remyelination is crucial to deciphering the molecular and cellular processes required to promote nerve repai
Publikováno v:
Physiological Reports
Adenosine operating in the nucleus of the solitary tract (NTS) may inhibit or facilitate neurotransmitter release from nerve terminals and directly inhibit or facilitate central neurons via A1 and A2a pre‐ and postsynaptic receptors, respectively.
Publikováno v:
European Journal of Neuroscience. 37:1705-1713
We have previously shown, in the rat, that neuropathic and inflammatory events produce a neuroplastic change in nociceptor function whereby a subsequent exposure to a proinflammatory mediator (e.g. prostaglandin E2 ; PGE2 ) produces markedly prolonge
Publikováno v:
Journal of Cellular Physiology. 227:3201-3207
Adenosine A1 receptor (A1R)-induced translocation of PKCe to transverse (t) tubular membranes in isolated rat cardiomyocytes is associated with a reduction in β1-adrenergic-stimulated contractile function. The PKCe-mediated activation of protein kin
Publikováno v:
Journal of Bone and Mineral Research. 26:2112-2124
Osteoblasts and adipocytes differentiate from a common precursor cell, the mesenchymal stem cell (MSC). Adenosine is known to signal via four adenosine receptor subtypes, and significantly, recent findings indicate that these may play a role in MSC d
Publikováno v:
Hippocampus. 21:265-280
Stellate neurons in layer II entorhinal cortex (EC) provide the main output from the EC to the hippocampus. It is believed that adenosine plays a crucial role in neuronal excitability and synaptic transmission in the CNS, however, the function of ade
Publikováno v:
European Journal of Immunology. 39:2895-2905
In intestine, neutrophils are recruited in response to bacterial infiltration and their anti-cellular activities contribute to inflammatory bowel diseases. In contrast, little is known regarding the recruitment of MPhi to the intestinal epithelium. E
Publikováno v:
British Journal of Pharmacology. 158:339-353
Background and purpose: Little is known about P2Y receptors in cardiac fibroblasts, which represent the predominant cell type in the heart and differentiate into myofibroblasts under certain conditions. Therefore, we have characterized the phenotype
Publikováno v:
Cell Biochemistry and Function. 26:833-843
Due to the lack of specific agonists and antagonists the role of adenosine receptor subtypes with respect to their effect on the insulin secretory system is not well investigated. The A1 receptor may be linked to different 2nd messenger systems, i.e.
Publikováno v:
Journal of Neurochemistry. 107:1369-1381
We have previously demonstrated that adenosine controls the release of catecholamines (CA) from carotid body (CB) acting on A2B receptors. Here, we have tested the hypothesis that the control is exerted via an interaction between adenosine A2B and do