Zobrazeno 11 - 20
of 74
pro vyhledávání: ''
Autor:
Mark Graham, Daniel L. Hertz, William J. Irvin, Joseph G. Ibrahim, Oludamilola Olajide, Karen E. Weck, James P. Evans, Allison M. Deal, Jeffrey Peppercorn, Christine M. Walko, Steven M. Anderson, Lisa A. Carey, David R. Jones, Susan E. Moore, Rachel Elizabeth Raab, Steven W. Corso, Zeruesenay Desta, Gustav Magrinat, David A. Flockhart, Daniel R. Carrizosa, Howard L. McLeod, Garry Schwartz
BACKGROUND Polymorphic CYP2D6 is primarily responsible for metabolic activation of tamoxifen to endoxifen. We previously reported that by increasing the daily tamoxifen dose to 40 mg/day in CYP2D6 intermediate metabolizer (IM), but not poor metaboliz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a10a5ebac4286ceaa1a874712d85930
Autor:
Lee R. Mobley, Tzy-Mey Kuo
We determined whether the current SEER registries are representative of the nation's cancer cases or the socio-demographic characteristics.We used breast cancer (BC) and colorectal cancer (CRC) cases diagnosed 2004-2009 from the US Cancer Statistics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61732860a1d319d0997a4259a056a4d8
Autor:
Suryanarayan Deo, Ramon Colomer, Sung Bae Kim, Soo-Chin Lee, Ajay O. Mehta, Bin Yao, Igor Bondarenko, Ron Bose, Chanchal Goswami, Lisa A. Carey, Feng Xu, Georgia Demetriou, Rajendra A. Badwe, Kenichi Inoue, Thomas Bachelot, Ahmad Awada, Alvin Wong, Richard Bryce
Importance Efficacious ERBB2 (formerly HER2 or HER2/neu)-directed treatments, in addition to trastuzumab and lapatinib, are needed. Objective To determine whether neratinib, an irreversible pan-ERBB tyrosine kinase inhibitor, plus paclitaxel improves
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90b13e12b4a93d6aa9fc5af99ad2b430
Autor:
Carey K. Anders, Eric P. Winer, Clifford A. Hudis, Katherine A. Hoadley, Lyndsay Harris, Ian E. Krop, William T. Barry, Brandelyn N. Pitcher, Donald A. Berry, Maggie C.U. Cheang, Lisa A. Carey, Norah Lynn Henry, Constance Cirrincione, Charles M. Perou, Michael D. Iglesia, David W. Ollila, Baljit Singh, Douglas Weckstein
Purpose Dual human epidermal growth factor receptor 2 (HER2) targeting can increase pathologic complete response rates (pCRs) to neoadjuvant therapy and improve progression-free survival in metastatic disease. CALGB 40601 examined the impact of dual
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0737f2439949512527a1f43c15b62506
Autor:
Christopher A. Haiman, Andrew F. Olshan, Elisa V. Bandera, Christine B. Ambrosone, Melissa A. Troester, Julie R. Palmer, Lynn Rosenberg, Song Yi Park, Emma Viscidi, Traci N. Bethea, Laurence N. Kolonel
Recent population studies suggest a role of smoking in the etiology of breast cancer, but few have been conducted among African American women. In a collaborative project of four large studies, we examined associations between smoking measures and br
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fc9b61889ac9a22f662a7c60fb3e664
Multivitamin, calcium and folic acid supplements and the risk of colorectal cancer in Lynch syndrome
Autor:
Stephen N. Thibodeau, Finlay A. Macrae, Alex Boussioutas, Susan Parry, Dennis J. Ahnen, Steven Gallinger, Graham G. Giles, Robert W. Haile, A. Joan Levine, Jane C. Figueiredo, Driss Ait Ouakrim, Rowena Chau, John L. Hopper, John D. Potter, Graham Casey, Christophe Rosty, Seyedeh Ghazaleh Dashti, John A. Baron, Joanne P. Young, Ingrid Winship, Polly A. Newcomb, Mark Clendenning, Mark A. Jenkins, Noralane M. Lindor, Aung Ko Win, Loic Le Marchand, Daniel D. Buchanan
People with a DNA mismatch repair (MMR) gene mutation have a substantially elevated risk of colorectal cancer (CRC) but the modifiers of this risk are not well established. We investigated the association between dietary supplement intake and CRC ris
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::088ca9e00da4ae9c47f7550e00fe2fc0
Autor:
Song Yao, Lynn Rosenberg, Song Liu, Tongguang Cheng, Christine B. Ambrosone, Chi Chen Hong, Melissa A. Troester, Julie R. Palmer, Qiang Hu, Stephen A. Haddad, Lara E. Sucheston-Campbell, Edward A. Ruiz-Narváez, Jeannette T. Bensen, Christopher A. Haiman, Kathryn L. Lunetta, Elisa V. Bandera, Andrew F. Olshan
The phosphatidylinositol 3-kinase-AKT-mammalian target of rapamycin (mTOR) pathway has been implicated in breast carcinogenesis. However, there has been no large-scale investigation of genetic variants in the mTOR pathway and breast cancer risk. We e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::670fb2f8369078f1583982c4cd042489
The effect of race on breast cancer outcome is confounded by tumor and treatment heterogeneity. We examined a cohort of women with stage II–III breast cancer treated uniformly with neoadjuvant chemotherapy to identify factors associated with racial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf1b86bb617200180af4224d3a67f7bc
Autor:
Andrew F. Olshan, Hazel B. Nichols, Melissa A. Troester, Xuezheng Sun, Mark E. Sherman, Whitney R. Robinson
Adiposity has been linked with increased breast cancer risk and mortality. It is established that etiologic associations for adiposity vary by tumor subtype, but the influence of adiposity on subtype-specific survival is unknown. Study participants w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1fe13f53585a58a5e6cbfd5962c53e5
Autor:
Alpa M. Nick, Hyun Jin Choi, Vahid Afshar-Kharghan, Behrouz Zand, Anil K. Sood, Justin Bottsford-Miller, Min Soon Cho, Chad V. Pecot, Sunila Pradeep, Rebecca L. Stone, Rebecca A. Previs, Erin K. Crane, Wei Hu, Monika Haemmerle, Heather J. Dalton, Susan K. Lutgendorf
Purpose: We hypothesized that platelet levels during therapy could serve as a biomarker for response to therapy and that manipulation of platelet levels could impact responsiveness to chemotherapy. Experimental Design: The medical records of patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fa39a18cd3e883750d838a69636c872