Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Holger Schmidt"'
Autor:
Aaron R. Hawkins, M. Harrington, Mohammad Julker Neyen Sampad, M. A. Stott, M. Rahman, T. D. Yuzvinsky, Holger Schmidt, Yucheng Li
Publikováno v:
Optica
We use optical trapping to deliver molecular targets to the vicinity of a nanopore for high-throughput single molecule analysis on an optofluidic chip. DNA detection rates increase over 80× to enable detection at attomolar concentrations.
Publikováno v:
Optica. 5:1311
Optical and optically assisted trapping has developed into an essential tool for studying and manipulating small objects with applications in numerous fields at the intersection of physics and the life sciences. Here, we report a waveguide-based opto
Publikováno v:
Optics Letters. 43:4425
Liquid-core waveguide-based optofluidic devices have proven to be valuable tools for analysis of biological samples in fluid. They have enabled single bioparticle sensitivity while maintaining in-plane detection via light-induced fluorescence. The in
Autor:
Alexandra Stambaugh, Joshua W. Parks, M. A. Stott, Holger Schmidt, Aaron R. Hawkins, G. G. Meena
Publikováno v:
Biomedical Optics Express. 9:3725
The recent massive Zika virus (ZIKV) outbreak illustrates the need for rapid and specific diagnostic techniques. Detecting ZIKV in biological samples poses unique problems: antibody detection of ZIKV is insufficient due to cross-reactivity of Zika an
Publikováno v:
Optics Letters. 40:5435
Optical manipulation of small particles in the form of trapping, pushing, or sorting has developed into a vast field with applications in the life sciences, biophysics, and atomic physics. Recently, there has been increasing effort toward integration
Autor:
Sergei Kühn, Evan J. Lunt, Philip Measor, Holger Schmidt, Brian S. Phillips, Aaron R. Hawkins
Publikováno v:
Optics Express. 17:24342
A new waveguide design for an optofluidic chip is presented. It mitigates multi-mode behavior in solid and liquid-core waveguides by increasing fundamental mode coupling to 82% and 95%, respectively. Additionally, we demonstrate a six-fold improvemen
Autor:
Evan J. Lunt, Aaron R. Hawkins, Holger Schmidt, Philip Measor, Brian S. Phillips, Sergei Kühn
Publikováno v:
Optics Letters. 33:672
We introduce a method for optical characterization of hollow-core optical waveguides. Radiation pressure exerted by the waveguide modes on dielectric microspheres is used to analyze salient properties such as propagation loss and waveguide mode profi
Publikováno v:
Optics Express. 15:7290
We demonstrate the implementation of fluorescence correlation spectroscopy (FCS) on a chip. Full planar integration is achieved by lithographic definition of sub-picoliter excitation volumes using intersecting solid and liquid-core optical waveguides
Publikováno v:
Optics Express. 13:10564
We present the characterization of the optical properties of integrated antiresonant reflecting optical (ARROW) waveguides with arch-shaped liquid cores. Optical mode shapes and coupling, waveguide loss, and polarization dependence are investigated.
Publikováno v:
Optics Express. 13:9331
We discuss optimization of the optical properties of hollow-core antiresonant reflecting optical waveguides (ARROWs). We demonstrate significant reduction of waveguide loss to 2.6/cm for a 10.4microm(2) mode area after adding an initial etching step