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Autor:
Barbara V. Howard, Nora Franceschini, Lyle G. Best, Terri H. Beaty, Karin Haack, Jean W. MacCluer, Ching-Wei Tsai, Ana Navas-Acien, Adrienne Tin, Ying Zhang, Kari E. North, Sandy Laston, V. Saroja Voruganti, W. H. Linda Kao
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 100:E345-E349
Context: Elevated LDL cholesterol (LDL-C) is an important risk factor for atherosclerosis and cardiovascular disease. Variants in the proprotein convertase subtilisin/kexin type 9 (PCSK9) gene have been associated not only with plasma LDL-C concentra