Zobrazeno 1 - 10
of 38
pro vyhledávání: '"35"'
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 55:727-733
Ten hormone-deficient hypoparathyroid children have been successfully treated with orally administered 1,25-dihydroxyvitamin D3 [1,25-(OH)2D3] within a dose range of 0.01--0.10 microgram/kg . day for a total of 35 patient yr. Resistance to 1,25-(OH)2
Publikováno v:
J Clin Endocrinol Metab
Purpose Aberrant thyroid function causes dysregulated metabolic homeostasis. Literature has demonstrated hypercoagulability in hypothyroidism, suggesting a risk for thromboembolic events (TEE). We hypothesize that individuals with hypothyroidism will
Autor:
David S, Hong, Maria E, Cabanillas, Jennifer, Wheler, Aung, Naing, Apostolia M, Tsimberidou, Lei, Ye, Naifa L, Busaidy, Steven G, Waguespack, Mike, Hernandez, Adel K, El Naggar, Alder K, El Naggar, Savita, Bidyasar, John, Wright, Steven I, Sherman, Razelle, Kurzrock
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 96:997-1005
Purpose: Ras/Raf/MAPK kinase/ERK and rearranged in transformation (RET) kinase pathways are important in thyroid cancer. We tested sorafenib, a B-Raf, RET, and vascular endothelial growth factor receptor kinase inhibitor, combined with tipifarnib, a
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 79:887-889
Reportedly between 8-38% of patients who receive bilateral adrenalectomy for treatment of Cushing's disease will develop Nelson's syndrome. We investigated which factors may predict the development of the syndrome. Eight of 48 patients, bilaterally a
Autor:
Mark Cadena, Quincy Eckert Harenda, Michelle E. Kimple, Harpreet K. Brar, Erin Laundre, Jaclyn A. Wisinski, Haley Wienkes, Rachel J. Fenske, Feyza Engin, Kathryn A. Carbajal, Jinjin Cai, Allison L. Brill, Timothy E. Graham, Michael D. Schaid, Nathan A. Truchan
Publikováno v:
Endocrinology. 158:1645-1658
The α-subunit of the heterotrimeric Gz protein, Gαz, promotes β-cell death and inhibits β-cell replication when pancreatic islets are challenged by stressors. Thus, we hypothesized that loss of Gαz protein would preserve functional β-cell mass
Autor:
Mark Kidd, Lisa Bodei, Irvin M. Modlin, Artur Sankowski, Agnieszka Kolasińska-Ćwikła, Jarosław B. Ćwikła
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 100:E1437-E1445
Context: Early and precise delineation of therapeutic responses are key issues in neuroendocrine neoplasm/tumor management. Imaging is currently used but exhibits limitations in sensitivity and specificity. The utility of biomarkers is unclear. Objec
Autor:
D L Loriaux, Robert Udelsman, Jeffrey A. Norton, George P. Chrousos, S E Jelenich, W M Linehan, David S. Goldstein
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 64:986-994
We studied the responses of plasma CRH, ACTH, cortisol, norepinephrine, epinephrine, and renin activity in 11 patients undergoing parathyroid or thyroid surgery after identical preoperative sedation and during isoflurane (Forane) anesthesia. During s
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 50:900-905
Male rhesus monkey fetuses have significantly more testosterone (T) in their circulation than females on days 35--50 of gestation (P less than 0.01; n = 6 males and 6 females). However, we found no sex differences for androstenedione (delta 4). T con
Autor:
Markus P. Schlaich, Carolina I. Sari, John Dixon, Nina Eikelis, Gavin W. Lambert, Mariee T. Grima, Nora E. Straznicky, Paul J. Nestel, Sarah E. Phillips, Elisabeth Lambert, Sofie Karapanagiotidis, Dagmara Hering
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 100:1544-1550
Impaired insulin clearance contributes to the hyperinsulinemia of obesity, yet relatively little is known concerning the pathophysiological determinants of insulin clearance in obese populations.To examine the cross-sectional relationship between ins
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 99:4481-4486
Proton-pump inhibitors (PPIs) impair tablet levothyroxine (LT4) intestinal absorption by increasing the gastric pH and decreasing LT4 dissolution in the stomach.The purpose of this study was to verify whether a liquid formulation of LT4 would correct