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Autor:
Robin A.J. Smith, Ellen L. Robb, Lesley Larsen, Cameron Evans, Andrew M. James, Peter G. Finichiu, Jan Trnka, Michael P. Murphy, David S. Larsen, Tracy A. Prime, Thomas P. Bright
Publikováno v:
Free Radical Biology & Medicine
Mitochondrial oxidative damage contributes to a wide range of pathologies. One therapeutic strategy to treat these disorders is targeting antioxidants to mitochondria by conjugation to the lipophilic triphenylphosphonium (TPP) cation. To date only hy