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pro vyhledávání: '"Yoshihiro Asano"'
Autor:
Makoto Kanoh, Hiroto Shinomiya, Yoshihiro Asano, Xin Xu, Mitsuharu Sato, Saho Maruyama, Hua Shen, Masahito Matsumoto, Kohsuke Sumita
Publikováno v:
The Journal of Immunology. 170:997-1001
IL-12 is a heterodimer composed of p40 and p35 and is a key cytokine that functions to protect the host from viral and microbial infections. IL-12 links the innate immune system with the acquired immune system during infection, and induces differenti
Publikováno v:
The Journal of Immunology. 182:135.15-135.15
[Purpose] Pathogen infection induces a shift to Th1 and inhibits a shift to Th2. The transcription factor IRF-1 is known to be essential for inducing IL-12 production and a shift to Th1. However, IRF-1 deficient cells express IL-12 p40 gene and induc
Autor:
Makoto Kanoh, Hau Shen, Saho Maruyama, Akira Matsumoto, Hiroto Shinomiya, Pascale Cossart, Werner Goebel, Yoshihiro Asano
Publikováno v:
The Journal of Immunology. 182:129.6-129.6
CD4+T cells are divided into four types according to the set of lymphokines they produce, i.e., Th1 cells, Th2 cells, Th17 cells and Treg cells. The differentiation process of T cells into each subset is controlled by cytokines produced during the in