Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Sophie Stephenson"'
Autor:
Matthew A. Care, Andy C. Rawstron, Gina M. Doody, Reuben Tooze, Sophie Stephenson, Adam Davison, Mario Cocco, David R. Westhead, Darren J. Newton, Nicholas A. Barnes
Publikováno v:
The Journal of Immunology. 189:5773-5785
Plasma cells (PCs), the terminal effectors of humoral immunity, are short-lived unless supported by niche environments in which they may persist for years. No model system has linked B cell activation with niche function to allow the in vitro generat
Publikováno v:
The Journal of Immunology. 189:253-260
During cellular differentiation, mRNA transcription and translation require precise coordination. The mechanisms controlling this are not well defined. IL-21 is an important regulator of plasma cell differentiation, and it controls the master regulat
Publikováno v:
The Journal of Immunology. 177:4584-4593
MHC class II is expressed in restricted lineages and is modulated in response to pathogens and inflammatory stimuli. This expression is controlled by MHC CIITA, which is transcribed from multiple promoters. Although factors required for induction of