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pro vyhledávání: '"Herbert J. Zeh"'
Autor:
Steven E. Winikoff, David L. Bartlett, Herbert J. Zeh, Kevin J. Tracey, Z. Sheng Guo, Charles K. Brown, Richard A. DeMarco, Arthur M. Krieg, Michael T. Lotze, Petar J. Popovic
Publikováno v:
The Journal of Immunology. 177:8701-8707
Plasmacytoid dendritic cells (PDC) are innate immune effector cells that are recruited to sites of chronic inflammation, where they modify the quality and nature of the adaptive immune response. PDCs modulate adaptive immunity in response to signals
High Avidity CTLs for Two Self-Antigens Demonstrate Superior In Vitro and In Vivo Antitumor Efficacy
Publikováno v:
The Journal of Immunology. 162:989-994
A majority of the human tumor-associated Ags characterized to date are derived from nonmutated “self”-proteins. Little is currently understood about the nature of the self-reactive lymphocytes that recognize these Ags. We recently characterized t
Autor:
Pawel Kalinski, Amer H. Zureikat, Ravikumar Muthuswamy, Natasa Obermajer, Julie Urban, Lisa H. Butterfield, William Gooding, Herbert J. Zeh, David L. Bartlett
Publikováno v:
The Journal of Immunology. 196:212.4-212.4
Infiltration of tumor lesions with effector CD8+ T cells (CTLs) has been shown to predict improved clinical outcomes in multiple cancer types and predict patients’ responsiveness to checkpoint blockers. In contrast, local prevalence of regulatory T