Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Ansuman T. Satpathy"'
Autor:
Saravanan Raju, Wayne M. Yokoyama, Kohei Kometani, Yu Xia, Takeshi Egawa, Ansuman T. Satpathy, Bence Daniel, Elliot Bradshaw, Daniel Verbaro, Elena Tonc, Kathryn E. Yost, Tomohiro Kurosaki
Publikováno v:
J Immunol
Persistent Ag induces a dysfunctional CD8 T cell state known as “exhaustion” characterized by PD-1 expression. Nevertheless, exhausted CD8 T cells retain functionality through continued differentiation of progenitor into effector cells. However,
Dissecting the genetic networks that control regulatory T cell stability using pooled CRISPR screens
Autor:
Jessica T. Cortez, Eric Shifrut, Youjin Lee, Maxwell R. Mumbach, Ansuman T. Satpathy, Jeffrey Granja, Meena Subramaniam, Theodore Roth, Dimitre Simeonov, Chun J. Ye, Howard Y. Chang, Frederic Van Gool, Alexander Marson
Publikováno v:
The Journal of Immunology. 200:101.5-101.5
Regulatory T cells (Tregs) are a specialized subset of CD4+ T cells that suppress inflammation to maintain homeostasis and prevent autoimmunity. Treg development and function depend on expression of the master transcription factor Foxp3. While Tregs
Autor:
Frederic Van Gool, Michelle L. Nguyen, Maxwell R. Mumbach, Ansuman T. Satpathy, Mark S. Anderson, Alexander Marson, Howard Y. Chang, Jeffrey A. Bluestone
Publikováno v:
The Journal of Immunology. 200:101.9-101.9
Regulatory T cells (Treg) play a fundamental role in maintaining immune tolerance. These cells are defined and characterized by expression of the master regulator Foxp3, a transcription factor that is crucial for Treg function and homeostasis. Natura