Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Anna Mae Diehl"'
Autor:
Jia Li, Anna Mae Diehl, Baojun Zhang, Deepthi Rajagopalan, Sandeep S. Dave, Cassandra Love, Anupama Reddy, Shibo Li, Yuan Zhuang, Young Mi Kim, Sumedha Roy
Publikováno v:
The Journal of Immunology. 198:3136-3148
Inhibitor of DNA binding (Id) proteins, including Id1–4, are transcriptional regulators involved in promoting cell proliferation and survival in various cell types. Although upregulation of Id proteins is associated with a broad spectrum of tumors,
High mobility group box 1 (HMGB1)-RAGE interaction mediates ectopic Intestinal inflammation in NAFLD
Autor:
VARUN CHANDRASHEKARAN, RATANESH K SETH, DIPTADIP DATTAROY, FIRAS ALHASSON, JACEK ZIELONKA, JAMES CARSON, FRANKLIN BERGER, BALARAMAN KALYANARAMAN, Anna Mae Diehl, Saurabh Chatterjee
Publikováno v:
The Journal of Immunology. 198:201.11-201.11
Recent clinical studies found a strong association of colonic inflammation with NAFLD yet the mechanisms remain largely unknown. The present study identifies HMGB1 as a key mediator of intestinal inflammation in NAFLD and outlines a detailed redox si
Autor:
Ratanesh K Seth, Varun Chandrashekaran, Diptadip Dattaroy, Firas Alhasson, Mitzi Nagarkatti, Prakash Nagarkatti, Anna Mae Diehl, Wolfgang Liedtke, Saurabh Chatterjee
Publikováno v:
The Journal of Immunology. 198:197.13-197.13
M1 macrophage polarization in nonalcoholic steatohepatitis (NASH) liver has been impacted by several exogenous or endogenous factors including inflammatory stimuli, oxidative stress, and cytokines. In absence of an active endogenous defense mechanism
Autor:
Diptadip Dattaroy, Varun Chandrashekaran Chandrashekaran, Ratanesh Kumar Seth, Firas Alhasson, Daping Fan, Mitzi Nagarkatti, Prakash Nagarkatti, Anna Mae Diehl, Saurabh Chatterjee
Publikováno v:
The Journal of Immunology. 198:197.10-197.10
Previous studies have shown that TLR4 activation accentuates hepatic inflammation and fibrosis in nonalcoholic steatohepatitis (NASH). Here we report an anti-fibrotic activity of Sparstolonin B (SsnB)-a TLR4 antagonist, derived from Chinese herb Spar