Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Thomas H"'
Autor:
Paul N. Bogner, Suresh Gopi Kalathil, Tariq A. Bhat, Paul V. Lehmann, Patricia J. Sime, Yasmin Thanavala, Thomas H. Thatcher
Publikováno v:
J Immunol
Cigarette smoke is a potent proinflammatory trigger contributing to acute lung injury and the development of chronic lung diseases via mechanisms that include the impairment of inflammation resolution. We have previously demonstrated that secondhand
Autor:
Paul N. Bogner, Richard P. Phipps, Suresh Gopi Kalathil, Yasmin Thanavala, Austin Miller, Thomas H. Thatcher, Paul V. Lehmann, Patricia J. Sime, Tariq A. Bhat
Publikováno v:
The Journal of Immunology. 200:2927-2940
Despite advocacy to reduce smoking-related diseases, >1 billion people worldwide continue to smoke. Smoking is immunosuppressive and an important etiological factor in the development of several human disorders including respiratory diseases like chr
Autor:
Yasmin Thanavala, Richard P. Phipps, Paul N. Bogner, Amit A. Lugade, Patricia J. Sime, Thomas H. Thatcher
Publikováno v:
The Journal of Immunology. 192:5226-5235
The detrimental impact of tobacco on human health is clearly recognized, and despite aggressive efforts to prevent smoking, close to one billion individuals worldwide continue to smoke. People with chronic obstructive pulmonary disease are susceptibl
Autor:
Natalya Subbotina, Jeremy K. Dayrit, Keely Browning, Gwo Hsiao Chen, Thomas H. Sisson, Yujing Lin, John R. Erb-Downward, Roger E. Morey, Jeffrey C. Horowitz, Benjamin J. Murdock, Michal A. Olszewski, John J. Osterholzer, Richard Simon
Publikováno v:
The Journal of Immunology. 190:3447-3457
The alveolar epithelium is characteristically abnormal in fibrotic lung disease, and we recently established a direct link between injury to the type II alveolar epithelial cell (AEC) and the accumulation of interstitial collagen. The mechanisms by w
Increased Ribonuclease Expression Reduces Inflammation and Prolongs Survival in TLR7 Transgenic Mice
Autor:
Jessica A. Hamerman, Jeffrey A. Ledbetter, Nalini Agrawal, Thomas H. Teal, Denny Liggitt, Charles E. Alpers, Matthew B. Buechler, Lena Tanaka, Kelly L. Hudkins, Xizhang Sun, Keith B. Elkon, Alice E. Wiedeman, Silvia Bolland
Publikováno v:
The Journal of Immunology. 190:2536-2543
TLR7 activation is implicated in the pathogenesis of systemic lupus erythematosus. Mice that overexpress TLR7 develop a lupus-like disease with autoantibodies and glomerulonephritis and early death. To determine whether degradation of the TLR7 ligand
Publikováno v:
The Journal of Immunology
Immune complexes (ICs) play a pivotal role in causing inflammation in systemic lupus erythematosus (SLE). Yet, it remains unclear what the dominant blood cell type(s) and inflammation-related gene programs stimulated by lupus ICs are. To address thes
Publikováno v:
The Journal of Immunology. 69:645-671
Summary In 1949, in preliminary notes, we recorded the fact that the in vitro propagation of the poliomyelitis viruses may be accomplished in suspended cell cultures of various types of human tissues. The present paper details the procedures we have