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of 145
pro vyhledávání: ''
Autor:
Pyeung-Hyeun Kim, Geun-Shik Lee, Seok-Rae Park, Ha-Eon Song, Seung-Goo Kang, Sung-il Yoon, Hyun-Jeong Ko, Goo-Young Seo, Young-Saeng Jang, Tae-Gyu Kim, Hui-Won Park, Sun-Hee Park, Hyeon-Ju Jo
Publikováno v:
The Journal of Immunology. 207:2456-2464
Lactoferrin (LF) is known to possess anti-inflammatory activity, although its mechanisms of action are not well-understood. The present study asked whether LF affects the commitment of inducible regulatory T cells (Tregs). LF substantially promoted F
Publikováno v:
J Immunol
Alcohol use disorders (AUD) increase susceptibility to respiratory infections by 2- to 4-fold in part because of impaired alveolar macrophage (AM) immune function. Alcohol causes AM oxidative stress, diminishing AM phagocytic capacity and clearance o
Autor:
Amanda Gruver-Yates, John A. Cidlowski, Carl D. Bortner, Maria Grazia Petrillo, Derek W. Cain, David Díaz-Jiménez
Publikováno v:
J Immunol
Glucocorticoids promote CXCR4 expression by T cells, monocytes, macrophages, and eosinophils, but it is not known if glucocorticoids regulate CXCR4 in B cells. Considering the important contributions of CXCR4 to B cell development and function, we in
Autor:
Peter J. Murray, Stefanie Dichtl, Roland Lang, Johanna Schäfer, Ursula R. Sorg, Dennis Christensen, Judith Schick, Klaus Pfeffer, Christian Alexander, Ulrike Schleicher
Publikováno v:
The Journal of Immunology. 205:323-328
TNF blockade is a successful treatment for human autoimmune disorders like rheumatoid arthritis and inflammatory bowel disease yet increases susceptibility to tuberculosis and other infections. The C-type lectin receptors (CLR) MINCLE, MCL, and DECTI
Publikováno v:
Journal of Immunology
Extracellular adenosine accumulates in tumors and causes suppression of immune cells. Suppressive adenosine signaling is achieved through adenosine A2A and A2B receptors, which are Gs coupled, and their activation elevates cAMP levels. Gs-coupled GPC
Autor:
Yanni Lv, Pengyu Ma, Priyanka Pundir, Ting Lei, Fang Fang, Haiyan Dong, Shengli Han, Jue Wang, Langchong He, Tao Zhang, Tingting Zhao, Delu Che, Jiao Cao, Liu Rui, Nan Wang, Xinzhong Dong
Publikováno v:
The Journal of Immunology. 203:1701-1714
Intrathecal morphine infusion is often applied to treat chronic pain related to cancer and other conditions. However, persistent pain can be caused by nerve compression because of granuloma formation. In this study, a mouse model of morphine-induced
Autor:
Wei Zhou, Aihua Lei, Jin-Yi Tang, Haikun Wang, Ting Liu, Wei-Ming Yuan, Maohua Shi, Yingjiao Cao, Ying Yu, Hui Zhang, Jie Zhou, Qiong Yang, Yongdong Liu, Pan Zhou, Quan Yang
Publikováno v:
The Journal of Immunology. 203:864-872
Cyclooxygenase (COX)-1, one of the critical enzymes required for the conversion of arachidonic acid to PGs, has been demonstrated to play an important role not only in the cardiovascular system but also in the immune system. COX-1 has been found to r
Autor:
Steven Dow, Daniel P. Regan, Lyndah Chow, Jade N. Kurihara, Jonathan Coy, Irina Kufareva, Kirti Kandhwal Chahal, Amanda Guth
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950), vol 202, iss 10
J Immunol
J Immunol
Inflammatory monocytes have been shown to play key roles in cancer metastasis through promotion of tumor cell extravasation, growth, and angiogenesis. Monocyte recruitment to metastases is mediated primarily via the CCL2–CCR2 chemotactic axis. Thus
Autor:
Shun'ichiro Taniguchi, Kenji Hata, Tomohiko Murakami, Eriko Nakamura, Masafumi Takahashi, Riko Nishimura, Hiroaki Okae, Yoshifumi Takahata, Lerdluck Ruengsinpinya
Publikováno v:
The Journal of Immunology. 202:1942-1947
The NLRP3 inflammasome has important roles in the pathogenesis of various inflammatory diseases. However, the regulatory mechanisms of the NLRP3 inflammasome are not fully understood. In this study, we attempted to identify molecules that interact wi
Autor:
Dhon Roméo Makanga, Catherine Willem, Marie C. Béné, Alice Garnier, Thierry Guillaume, Katia Gagne, Anne Cesbron, Nolwenn Legrand, Christelle Retière, Bercelin Maniangou, Amandine Le Bourgeois, Patrice Chevallier, Pierre Peterlin
Publikováno v:
Journal of Immunology
Journal of Immunology, 2019, 202 (7), pp.2141-2152. ⟨10.4049/jimmunol.1801489⟩
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2019, 202 (7), pp.2141-2152. ⟨10.4049/jimmunol.1801489⟩
Journal of Immunology, 2019, 202 (7), pp.2141-2152. ⟨10.4049/jimmunol.1801489⟩
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2019, 202 (7), pp.2141-2152. ⟨10.4049/jimmunol.1801489⟩
P.C. and C.R. have equally contributed to this work; International audience; Little is known regarding the effect of KIR/HLA incompatibilities (inc.) in the setting of T-replete haploidentical allogeneic he-matopoietic stem cell transplantation using