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pro vyhledávání: '"Richard A, Koup"'
Autor:
Mario Roederer, Fabien X. Lü, Richard A. Koup, Stephen P. Perfetto, Susan Moser, Joanne Yu, Judith Falloon, Christopher J. Miller, Thomas G. Evans, Stephen C. De Rosa
Publikováno v:
The Journal of Immunology. 173:5372-5380
In recent years, the quantification of T cell responses to pathogens or immunogens has become a common tool in the evaluation of disease pathogenesis or vaccine immunogenicity. Such measurements are usually limited to enumerating IFN-γ-producing cel
Autor:
John Hegarty, Daniel C. Douek, Jacinta Kelly, Cliona O'Farrelly, Richard A. Koup, Lucy Golden-Mason
Publikováno v:
The Journal of Immunology. 172:5980-5985
Normal adult human liver (AHL) contains populations of unconventional lymphocytes that have been shown in the mouse to mature locally. The presence of lymphoid progenitors together with IL-7, recombinase-activating gene, and pre-TCR-α expression in
Publikováno v:
The Journal of Immunology. 172:2219-2224
Langerhans cells (LC) are likely initial targets for HIV following sexual exposure to virus and provide an efficient means for HIV to gain access to lymph node T cells. The purpose of this study was to examine the nature of the CD4+ T cell that becom