Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Richard A, Koup"'
Autor:
Karin Loré, Gunilla B. Karlsson Hedestam, Martina Soldemo, Anna Smed-Sörensen, Leif Perbeck, Mattias N. E. Forsell, Richard A. Koup, William C. Adams, Kerrie J. Sandgren, Richard T. Wyatt, Frank Liang
Publikováno v:
The Journal of Immunology. 191:60-69
Advances in HIV-1 vaccine clinical trials and preclinical research indicate that the virus envelope glycoproteins (Env) are likely to be an essential component of a prophylactic vaccine. Efficient Ag uptake and presentation by dendritic cells (DCs) i
Autor:
Robert A. Seder, Bernard Moss, Linda S. Wyatt, Patricia A. Darrah, Cecilia Morgan, Wing Pui Kong, Antonella Folgori, Ayako Yamamoto, Dana Berry, Mariano Esteban, Kylie M. Quinn, Lingshu Wang, Ross W. B. Lindsay, Jason G. D. Gall, Cheng Cheng, Robert T. Bailer, Richard A. Koup, Alfredo Nicosia, Carmen E. Gómez, Riccardo Cortese, Andreia Costa, David Price, Emma Gostick, Mario Roederer, Stefano Colloca, Gary J. Nabel
Publikováno v:
The Journal of Immunology. 190:2720-2735
Recombinant adenoviral vectors (rAds) are the most potent recombinant vaccines for eliciting CD8+ T cell–mediated immunity in humans; however, prior exposure from natural adenoviral infection can decrease such responses. In this study we show low s
Autor:
Viraj Kulkarni, David Price, J. Joseph Melenhorst, Daniel C. Douek, Jeffrey M. Jacobson, Constantinos Petrovas, George N. Pavlakis, Benjamin Chaon, David R. Ambrozak, Pratip K. Chattopadhyay, Mario Roederer, Yvonne M. Mueller, Peter D. Katsikis, Richard A. Koup, Joseph P. Casazza, Christof Geldmacher, Brenna J. Hill, Barbara K. Felber
Publikováno v:
The Journal of Immunology. 183:1120-1132
Recent studies have revealed the critical role of programmed death-1 (PD-1) in exhaustion of HIV- and SIV-specific CD8+ T cells. In this study, we show that high expression of PD-1 correlates with increased ex vivo spontaneous and CD95/Fas-induced ap
Autor:
Carolyn Williamson, Koleka Mlisana, Richard A. Koup, Mandla Mlotshwa, Salim S. Abdool Karim, Debra de Assis Rosa, Catherine Riou, Wendy A. Burgers, Clive M. Gray, Guy de Bruyn, Pholo Maenetje, Mario Roederer, Daniel C. Douek, Jason M. Brenchley
Publikováno v:
The Journal of Immunology. 182:4751-4761
Understanding early immunological events during HIV-1 infection that may set the course of disease progression is important for identifying correlates of viral control. This study explores the association of differentiation profiles of HIV-specific a