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Publikováno v:
Bioengineered
article-version (VoR) Version of Record
Bioengineered, Vol 12, Iss 2, Pp 9128-9139 (2021)
article-version (VoR) Version of Record
Bioengineered, Vol 12, Iss 2, Pp 9128-9139 (2021)
The cold-shock protein Y-box-binding protein (YB)-1 regulates the expression of various chemokines and their receptors at the transcriptional level. Expression of the orphan chemokine CXCL14 is repressed by EGF induced signaling. The possible links b
Publikováno v:
Bioengineered
article-version (VoR) Version of Record
Bioengineered, Vol 12, Iss 2, Pp 12891-12904 (2021)
article-version (VoR) Version of Record
Bioengineered, Vol 12, Iss 2, Pp 12891-12904 (2021)
Umbilical cord mesenchymal stem cells (UCMSCs) are regarded as an ideal source for clinical use. Increasing evidence has suggested that microRNAs (miRNAs) work as a crucial regulator in the development of plentiful diseases, including intrauterine ad
Publikováno v:
Bioengineered
article-version (VoR) Version of Record
Bioengineered, Vol 12, Iss 2, Pp 12123-12134 (2021)
article-version (VoR) Version of Record
Bioengineered, Vol 12, Iss 2, Pp 12123-12134 (2021)
Objective The molecular mechanism that triggers polycystic ovary syndrome (PCOS) is mysterious. Abnormal development of ovarian granulosa cells(GCs) is one of the causes of PCOSMethods The study was carried out by using RNA-seq to detect the differen
Publikováno v:
Bioengineered
article-version (VoR) Version of Record
Bioengineered, Vol 12, Iss 2, Pp 11007-11017 (2021)
article-version (VoR) Version of Record
Bioengineered, Vol 12, Iss 2, Pp 11007-11017 (2021)
Osteosarcoma is one of the most common primary malignant tumors of bone in adolescents. Human umbilical vein endothelial cells (HUVECs) derived exosomes are associated with osteosarcoma cell stemness. Little is known about the function of HUVECs-exos
Autor:
Jiutao Qiao, Dan Liu, Qiang Fu, Zhijia Zhang, Xiaoyang Hu, Yanyu Gao, Yin Fu, Kai Li, Qingpeng Liu
Publikováno v:
Bioengineered
article-version (VoR) Version of Record
Bioengineered, Vol 12, Iss 1, Pp 7714-7723 (2021)
article-version (VoR) Version of Record
Bioengineered, Vol 12, Iss 1, Pp 7714-7723 (2021)
Osteoporosis (OP) is a systemic bone metabolic disease. Promotion of osteoblast proliferation and inhibition of cell apoptosis may be helpful for the prevention and clinical treatment of OP. In the current study, we focused on the expression changes
Autor:
Shu Dai, Zhenhong Zhu, Qian-wei Xiong, Hongliang Xia, Xiangming Yan, Shi-zhong Cai, Wei Liu, Zhou-rui Ma
Publikováno v:
Bioengineered
article-version (VoR) Version of Record
Bioengineered, Vol 12, Iss 1, Pp 6448-6458 (2021)
article-version (VoR) Version of Record
Bioengineered, Vol 12, Iss 1, Pp 6448-6458 (2021)
Human melanoma is a highly aggressive type of cancer, causing significant mortalities despite the advances in treatment. Carboplatin is a cisplatin analog necessary for the treatment of various cancers and can also be used to treat human melanoma. We
Publikováno v:
Bioengineered
article-version (VoR) Version of Record
Bioengineered, Vol 12, Iss 1, Pp 6923-6934 (2021)
article-version (VoR) Version of Record
Bioengineered, Vol 12, Iss 1, Pp 6923-6934 (2021)
Emerging studies have demonstrated notable roles of CCL20 in breast cancer progression. Based on these findings, CCL20 has become a potential therapeutic target for cancer immunotherapy. Accordingly, studies utilizing monoclonal antibodies to target
Autor:
Jian Song, Sai-Yang Zhang, Jin-Bo Niu, Chun-Quan Hua, Cheng-Yun Jin, Jia-Jia Yang, Yan-Bing Zhang, Guang-Xi Yu, Yuan Liu, Ying-Qiu Qi, Yin-Ru Li
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry
article-version (VoR) Version of Record
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 1715-1731 (2021)
article-version (VoR) Version of Record
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 1715-1731 (2021)
Hippo signalling pathway plays a crucial role in tumorigenesis and cancer progression. In this work, we identified an N-aryl sulphonamide-quinazoline derivative, compound 9i as an anti-gastric cancer agent, which exhibited potent antiproliferative ab
Autor:
Peifang Yang, Hui Wang, Meina Yan, Xinxin Yang, Sheng Xia, Guanghua Zhai, Rong Shen, Mutian Han, Lubin Zhang, Qixiang Shao
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry
article-version (VoR) Version of Record
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 1905-1915 (2021)
article-version (VoR) Version of Record
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 1905-1915 (2021)
Epidermal growth factor receptor (EGFR) signalling and the interleukin-6 (IL-6)/signal transducer and activator of transcription 3 (STAT3) are aberrantly activated in ovarian cancer. However, inhibition of EGFR signalling in ovarian cancer patients r
Publikováno v:
Bioengineered
article-version (VoR) Version of Record
Bioengineered, Vol 12, Iss 1, Pp 4081-4091 (2021)
article-version (VoR) Version of Record
Bioengineered, Vol 12, Iss 1, Pp 4081-4091 (2021)
Gastric cancer is one of the most common malignant tumors. Long non-coding RNAs play crucial roles in gastric cancer progression. This study investigated the effect of LINC01320 on malignant behaviors of gastric cancer cells and explored its possible